Linking interleukin-6 receptor blockade with tocilizumab and its hematological effects using a modeling approach.
about
Interleukin 6 blockage-induced neutropenia in a patient with rheumatoid arthritis and resolved hepatitis BPopulation pharmacokinetic and pharmacodynamic analysis of BIIB023, an anti-TNF-like weak inducer of apoptosis (anti-TWEAK) monoclonal antibody.The role of tocilizumab in the management of rheumatoid arthritis.Clinical Pharmacokinetics and Pharmacodynamics of Monoclonal Antibodies Approved to Treat Rheumatoid Arthritis.AFIR: A Dimensionless Potency Metric for Characterizing the Activity of Monoclonal Antibodies.Systems pharmacology and enhanced pharmacodynamic models for understanding antibody-based drug action and toxicity.A cell-level model of pharmacodynamics-mediated drug disposition.A Tutorial on Target-Mediated Drug Disposition (TMDD) Models.Effect of tofacitinib, a Janus kinase inhibitor, on haematological parameters during 12 weeks of psoriasis treatment.Analysis of haematological changes in tofacitinib-treated patients with rheumatoid arthritis across phase 3 and long-term extension studies.Successful application of belimumab in two patients with systemic lupus erythematosus experiencing a flare during tocilizumab treatment.
P2860
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P2860
Linking interleukin-6 receptor blockade with tocilizumab and its hematological effects using a modeling approach.
description
2011 nî lūn-bûn
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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name
Linking interleukin-6 receptor ...... cts using a modeling approach.
@en
Linking interleukin-6 receptor ...... cts using a modeling approach.
@nl
type
label
Linking interleukin-6 receptor ...... cts using a modeling approach.
@en
Linking interleukin-6 receptor ...... cts using a modeling approach.
@nl
prefLabel
Linking interleukin-6 receptor ...... cts using a modeling approach.
@en
Linking interleukin-6 receptor ...... cts using a modeling approach.
@nl
P2860
P1476
Linking interleukin-6 receptor ...... cts using a modeling approach.
@en
P2093
Leonid Gibiansky
Nicolas Frey
P2860
P2888
P356
10.1007/S10928-011-9227-Z
P577
2011-11-19T00:00:00Z