Familial chilblain lupus due to a gain-of-function mutation in STING. - Wikidata - awgldk - TriplyDB

Familial chilblain lupus due to a gain-of-function mutation in STING.

Familial chilblain lupus due to a gain-of-function mutation in STING.

http://www.wikidata.org/entity/Q51547437

about

Crosstalk Between Apoptosis and Autophagy: Environmental Genotoxins, Infection, and Innate Immunity.Type I interferon-mediated monogenic autoinflammation: The type I interferonopathies, a conceptual overview Lack of Trex1 Causes Systemic Autoimmunity despite the Presence of Antiretroviral Drugs.Insights from Mendelian Interferonopathies: Comparison of CANDLE, SAVI with AGS, Monogenic Lupus.cGAS-cGAMP-STING: The three musketeers of cytosolic DNA sensing and signaling.Monogenic Lupus.JAK inhibitors in dermatology: The promise of a new drug class.Immune Diseases Associated with TREX1 and STING Dysfunction.Regulating STING in health and disease Genomics, Biology, and Human Illness: Advances in the Monogenic Autoinflammatory Diseases.The monogenic autoinflammatory diseases define new pathways in human innate immunity and inflammation.Methods of Assessing STING Activation and Trafficking.Autoimmune phenotype with type I interferon signature in two brothers with ADA2 deficiency carrying a novel CECR1 mutation.Herpes Zoster and Tofacitinib: Clinical Outcomes and the Risk of Concomitant Therapy.cGAS-STING Activation in the Tumor Microenvironment and Its Role in Cancer Immunity.Response to: 'JAK inhibition in STING-associated interferonopathy' by Crow et al.STING-associated vasculopathy develops independently of IRF3 in mice.Cell Death, Nucleic acids and Immunity: Inflammation beyond the Grave.Recent developments in systemic lupus erythematosus pathogenesis and applications for therapy.A novel transcript isoform of STING that sequesters cGAMP and dominantly inhibits innate nucleic acid sensing.Pro-inflammation Associated with a Gain-of-Function Mutation (R284S) in the Innate Immune Sensor STING.JAK1/2 inhibition with baricitinib in the treatment of autoinflammatory interferonopathies.JAK inhibition in STING-associated interferonopathy

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P2860

Familial chilblain lupus due to a gain-of-function mutation in STING.

http://www.wikidata.org/entity/Q51547437

description

2016 nî lūn-bûn

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2016年の論文

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年学术文章

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2016年學術文章

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2016年學術文章

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name

Familial chilblain lupus due to a gain-of-function mutation in STING.

@en

Familial chilblain lupus due to a gain-of-function mutation in STING.

@nl

type

label

Familial chilblain lupus due to a gain-of-function mutation in STING.

@en

Familial chilblain lupus due to a gain-of-function mutation in STING.

@nl

prefLabel

Familial chilblain lupus due to a gain-of-function mutation in STING.

@en

Familial chilblain lupus due to a gain-of-function mutation in STING.

@nl

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P356

ANNRHEUMDIS-2016-209841

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Annals of the Rheumatic Diseases

P1476

Familial chilblain lupus due to a gain-of-function mutation in STING.

@en

P2093

Christine Wolf

http://www.w3.org/2001/XMLSchema#string

Christoph Fiehn

http://www.w3.org/2001/XMLSchema#string

Claudia Günther

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Emanuel Cura Costa

http://www.w3.org/2001/XMLSchema#string

Hugo Ariel Alvarez

http://www.w3.org/2001/XMLSchema#string

Kerstin Engel

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Max Schuster

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Min Ae Lee-Kirsch

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Nadja König

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Raphaela Goldbach-Mansky

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P2860

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response

Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system

Trex1 prevents cell-intrinsic initiation of autoimmunity

Regulation of type I interferon responses

Structural Analysis of the STING Adaptor Protein Reveals a Hydrophobic Dimer Interface and Mode of Cyclic di-GMP Binding

Ruxolitinib versus standard therapy for the treatment of polycythemia vera.

Activated STING in a vascular and pulmonary syndrome

STING and the innate immune response to nucleic acids in the cytosol.

SAMHD1 prevents autoimmunity by maintaining genome stability.

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468-472

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scholarly article

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10.1136/ANNRHEUMDIS-2016-209841

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2

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