Sulfoxidation of mercapturic acids derived from tri- and tetrachloroethene by cytochromes P450 3A: a bioactivation reaction in addition to deacetylation and cysteine conjugate beta-lyase mediated cleavage.
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Abundant Rodent Furan-Derived Urinary Metabolites Are Associated with Tobacco Smoke Exposure in Humans.Role of reactive metabolites in the circulation in extrahepatic toxicityHuman health effects of tetrachloroethylene: key findings and scientific issuesTransport of N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine, a metabolite of trichloroethylene, by mouse multidrug resistance associated protein 2 (Mrp2).Metabolism of trichloroethyleneModes of action of trichloroethylene for kidney tumorigenesis.Trichloroethylene biotransformation and its role in mutagenicity, carcinogenicity and target organ toxicity.N-biotinyl-S-(1,2-dichlorovinyl)-L-cysteine sulfoxide as a potential model for S-(1,2-dichlorovinyl)-L-cysteine sulfoxide: characterization of stability and reactivity with glutathione and kidney proteins in vitro.Characterization of the chemical reactivity and nephrotoxicity of N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine sulfoxide, a potential reactive metabolite of trichloroethyleneGlobin monoadducts and cross-links provide evidence for the presence of S-(1,2-dichlorovinyl)-L-cysteine sulfoxide, chlorothioketene, and 2-chlorothionoacetyl chloride in the circulation in rats administered S-(1,2-dichlorovinyl)-L-cysteine.Three common pathways of nephrotoxicity induced by halogenated alkenes.Studies on the inhibition of human cytochromes P450 by selenocysteine Se-conjugates.Rapid detection and identification of N-acetyl-L-cysteine thioethers using constant neutral loss and theoretical multiple reaction monitoring combined with enhanced product-ion scans on a linear ion trap mass spectrometer.Characterization of inter-tissue and inter-strain variability of TCE glutathione conjugation metabolites DCVG, DCVC, and NAcDCVC in the mouse.Liquid chromatography/electrospray ionisation mass spectrometric tracking of 4-hydroxy-2(E)-nonenal biotransformations by mouse colon epithelial cells using [1,2-13C2]-4-hydroxy-2(E)-nonenal as stable isotope tracer.
P2860
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P2860
Sulfoxidation of mercapturic acids derived from tri- and tetrachloroethene by cytochromes P450 3A: a bioactivation reaction in addition to deacetylation and cysteine conjugate beta-lyase mediated cleavage.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh-hant
name
Sulfoxidation of mercapturic a ...... beta-lyase mediated cleavage.
@en
Sulfoxidation of mercapturic a ...... beta-lyase mediated cleavage.
@nl
type
label
Sulfoxidation of mercapturic a ...... beta-lyase mediated cleavage.
@en
Sulfoxidation of mercapturic a ...... beta-lyase mediated cleavage.
@nl
prefLabel
Sulfoxidation of mercapturic a ...... beta-lyase mediated cleavage.
@en
Sulfoxidation of mercapturic a ...... beta-lyase mediated cleavage.
@nl
P2093
P356
P1476
Sulfoxidation of mercapturic a ...... beta-lyase mediated cleavage.
@en
P2093
P356
10.1021/TX950075U
P577
1996-01-01T00:00:00Z