Kinetic interaction analysis of human interleukin 5 receptor alpha mutants reveals a unique binding topology and charge distribution for cytokine recognition.
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Comparative modelling of protein structure and its impact on microbial cell factories.Structural basis of interleukin-5 dimer recognition by its α receptorCharacterization of the interaction between interleukin-13 and interleukin-13 receptorsA new isoform of interleukin-3 receptor {alpha} with novel differentiation activity and high affinity binding modeReceptor epitope usage by an interleukin-5 mimetic peptide.Asymmetric usage of antagonist charged residues drives interleukin-5 receptor recruitment but is insufficient for receptor activationThe role of interchain heterodisulfide formation in activation of the human common beta and mouse betaIL-3 receptors.The GM-CSF/IL-3/IL-5 cytokine receptor family: from ligand recognition to initiation of signaling.Slow, reversible, coupled folding and binding of the spectrin tetramerization domain.Interleukin-5 receptor subunit oligomerization and rearrangement revealed by fluorescence resonance energy transfer imagingSlow-dissociation effect of common signaling subunit beta c on IL5 and GM-CSF receptor assembly.Molecular and clinical rationale for therapeutic targeting of interleukin-5 and its receptor.Efficacy and Safety of Benralizumab, a Monoclonal Antibody against IL-5Rα, in Uncontrolled Eosinophilic Asthma.The Ig-like domain of human GM-CSF receptor alpha plays a critical role in cytokine binding and receptor activation.Pharmacokinetic/pharmacodynamic drug evaluation of benralizumab for the treatment of asthma.Benralizumab: From the Basic Mechanism of Action to the Potential Use in the Biological Therapy of Severe Eosinophilic Asthma.Benralizumab in the treatment of severe asthma: design, development and potential place in therapy.
P2860
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P2860
Kinetic interaction analysis of human interleukin 5 receptor alpha mutants reveals a unique binding topology and charge distribution for cytokine recognition.
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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@zh
2003年学术文章
@zh-cn
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@zh-hans
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@zh-my
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@zh-sg
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@yue
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@zh-hant
name
Kinetic interaction analysis o ...... tion for cytokine recognition.
@en
Kinetic interaction analysis o ...... tion for cytokine recognition.
@nl
type
label
Kinetic interaction analysis o ...... tion for cytokine recognition.
@en
Kinetic interaction analysis o ...... tion for cytokine recognition.
@nl
prefLabel
Kinetic interaction analysis o ...... tion for cytokine recognition.
@en
Kinetic interaction analysis o ...... tion for cytokine recognition.
@nl
P2093
P2860
P356
P1476
Kinetic interaction analysis o ...... tion for cytokine recognition.
@en
P2093
Irwin Chaiken
Jeffery Scibek
Tetsuya Ishino
P2860
P304
P356
10.1074/JBC.M309327200
P407
P577
2003-12-07T00:00:00Z