Cancer and the blood-brain barrier: 'Trojan horses' for courses?A non-covalently cross-linked chitosan based hydrogel.Quaternary ammonium palmitoyl glycol chitosan--a new polysoap for drug delivery.Gene delivery with synthetic (non viral) carriers.Nanotechnology in advanced drug delivery.Dendrimers in gene delivery.Health economic burden that wounds impose on the National Health Service in the UKPharmaceutical nanotechnology: polymeric vesicles for drug and gene delivery.Lomustine Nanoparticles Enable Both Bone Marrow Sparing and High Brain Drug Levels - A Strategy for Brain Cancer TreatmentsPolyhedral non-ionic surfactant vesicles.Amphiphilic poly(L-amino acids) - new materials for drug delivery.Nanomedicines and nanodiagnostics come of age.Strategies to deliver peptide drugs to the brain.Limiting the level of tertiary amines on polyamines leads to biocompatible nucleic acid vectors.Direct in vivo evidence on the mechanism by which nanoparticles facilitate the absorption of a water insoluble, P-gp substrate.Nose to brain delivery in rats: Effect of surface charge of rhodamine B labeled nanocarriers on brain subregion localization.A nano-enabled cancer-specific ITCH RNAi chemotherapy booster for pancreatic cancer.Optimisation of synthetic vector systems for cancer gene therapy - the role of the excess of cationic dendrimer under physiological conditions.Dextran-pegylated microparticles for enhanced cellular uptake of hydrophobic drugs.Polyamine aza-cyclic compounds demonstrate anti-proliferative activity in vitro but fail to control tumour growth in vivo.Synthetic anticancer gene medicine exploits intrinsic antitumor activity of cationic vector to cure established tumors.Gene transfer with three amphiphilic glycol chitosans--the degree of polymerisation is the main controller of transfection efficiency.Preferential liver gene expression with polypropylenimine dendrimers.PEI-based vesicle-polymer hybrid gene delivery system with improved biocompatibility.Anticancer drug delivery with transferrin targeted polymeric chitosan vesicles.In vitro and in vivo gene transfer with poly(amino acid) vesicles.The lower-generation polypropylenimine dendrimers are effective gene-transfer agents.Niosomes and polymeric chitosan based vesicles bearing transferrin and glucose ligands for drug targeting.Adverse drug events related to dosage forms and delivery systems.The activity of doxorubicin niosomes against an ovarian cancer cell line and three in vivo mouse tumour models.Preparation and in vitro/in vivo evaluation of luteinizing hormone releasing hormone (LHRH)-loaded polyhedral and spherical/tubular niosomes.Preliminary characterization of novel amino acid based polymeric vesicles as gene and drug delivery agents.In silico modelling of drug-polymer interactions for pharmaceutical formulations.The molecular shape of poly(propylenimine) dendrimer amphiphiles has a profound effect on their self assembly.The release of model macromolecules may be controlled by the hydrophobicity of palmitoyl glycol chitosan hydrogels.Sustained buccal delivery of the hydrophobic drug denbufylline using physically cross-linked palmitoyl glycol chitosan hydrogels.Quantification of beta-galactosidase activity after non-viral transfection in vivo.Glucose-receptor MR imaging of tumors: study in mice with PEGylated paramagnetic niosomes.Glucose-targeted niosomes deliver vasoactive intestinal peptide (VIP) to the brain.Cancer-specific transgene expression mediated by systemic injection of nanoparticles.
P50
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P50
description
Professor of Pharmacy
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pharmacologue
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wetenschapper
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Ijeoma Uchegbu
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Ijeoma Uchegbu
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Ijeoma Uchegbu
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Ijeoma Uchegbu
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Ijeoma Uchegbu
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Ijeoma Uchegbu
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Ijeoma Uchegbu
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Ijeoma Uchegbu
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Ijeoma Uchegbu
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Ijeoma Uchegbu
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Ijeoma Uchegbu
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Ijeoma Uchegbu
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Ijeoma Uchegbu
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Ijeoma Uchegbu
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Ijeoma Uchegbu
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Ijeoma Uchegbu
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I Uchegbu
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I. F. Uchegbu
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I. Uchegbu
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Ijeoma F Uchegbu
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Ijeoma F. Uchegbu
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Ijeoma Florence Uchegbu
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Uchegbu I
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Ijeoma Uchegbu
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Ijeoma Uchegbu
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Ijeoma Uchegbu
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Ijeoma Uchegbu
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Ijeoma Uchegbu
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Ijeoma Uchegbu
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Ijeoma Uchegbu
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Ijeoma Uchegbu
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