MLL-AF9 Expression in Hematopoietic Stem Cells Drives a Highly Invasive AML Expressing EMT-Related Genes Linked to Poor Outcome.
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Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition.RUNX1-ETO and RUNX1-EVI1 Differentially Reprogram the Chromatin Landscape in t(8;21) and t(3;21) AML.Prognostic Significance of Mixed-Lineage Leukemia (MLL) Gene Detected by Real-Time Fluorescence Quantitative PCR Assay in Acute Myeloid Leukemia.EMT- and MET-related processes in nonepithelial tumors: importance for disease progression, prognosis, and therapeutic opportunities.AML1/ETO accelerates cell migration and impairs cell-to-cell adhesion and homing of hematopoietic stem/progenitor cells.Eya2, a Target Activated by Plzf, Is Critical for PLZF-RARA-Induced Leukemogenesis.Mouse models of MLL leukemia: recapitulating the human diseaseDysregulation of haematopoietic stem cell regulatory programs in acute myeloid leukaemia.CRISPR-Cas9-induced t(11;19)/MLL-ENL translocations initiate leukemia in human hematopoietic progenitor cells in vivo.Active hexose-correlated compound enhances extrinsic-pathway-mediated apoptosis of Acute Myeloid Leukemic cells.Transcriptional memory of cells of origin overrides β-catenin requirement of MLL cancer stem cells.An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance.Comment on: Genomics of primary chemoresistance and remission induction failure in paediatric and adult acute myeloid leukaemia.Trib2 expression in granulocyte-monocyte progenitors drives a highly drug resistant acute myeloid leukaemia linked to elevated Bcl2.Reprogramming Tumor-Immune Cell Interface in Solid and Hematological Malignancies to Enhance Response to Therapy.Upregulation of the EMT marker vimentin is associated with poor clinical outcome in acute myeloid leukemia.Human MLL-AF9 Overexpression Induces Aberrant Hematopoietic Expansion in Zebrafish.Dysregulated transcriptional networks in and -rearranged T-ALLCancer stem cells in progression of colorectal cancerCTCF boundary remodels chromatin domain and drives aberrant gene transcription in acute myeloid leukemia
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P2860
MLL-AF9 Expression in Hematopoietic Stem Cells Drives a Highly Invasive AML Expressing EMT-Related Genes Linked to Poor Outcome.
description
2016 nî lūn-bûn
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2016年の論文
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2016年学术文章
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2016年学术文章
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2016年学术文章
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2016年学术文章
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2016年学术文章
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2016年学术文章
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2016年學術文章
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2016年學術文章
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name
MLL-AF9 Expression in Hematopo ...... Genes Linked to Poor Outcome.
@en
MLL-AF9 Expression in Hematopo ...... Genes Linked to Poor Outcome.
@nl
type
label
MLL-AF9 Expression in Hematopo ...... Genes Linked to Poor Outcome.
@en
MLL-AF9 Expression in Hematopo ...... Genes Linked to Poor Outcome.
@nl
prefLabel
MLL-AF9 Expression in Hematopo ...... Genes Linked to Poor Outcome.
@en
MLL-AF9 Expression in Hematopo ...... Genes Linked to Poor Outcome.
@nl
P2093
P50
P1433
P1476
MLL-AF9 Expression in Hematopo ...... d Genes Linked to Poor Outcome
@en
P2093
Antoine H F M Peters
Hélène Royo
Juerg Schwaller
Laurent Brault
Mathijs A Sanders
Michelina Iacovino
Peter J M Valk
Sabine Juge
Stefano Morettini
Susanne Kaspar
P356
10.1016/J.CCELL.2016.05.011
P577
2016-06-23T00:00:00Z