A novel oral neutrophil elastase inhibitor (ONO-6818) inhibits human neutrophil elastase-induced emphysema in rats.
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Evidences of Herbal Medicine-Derived Natural Products Effects in Inflammatory Lung DiseasesAcute respiratory distress syndrome and lung injury: Pathogenetic mechanism and therapeutic implicationFunctional and morphological assessment of early impairment of airway function in a rat model of emphysemaA treatment with a protease inhibitor recombinant from the cattle tick (Rhipicephalus Boophilus microplus) ameliorates emphysema in mice.Novel therapies for the treatment of inflammatory airway disease.Chronic obstructive pulmonary disease, pollution, pulmonary vascular disease, transplantation, pleural disease, and lung cancer in AJRCCM 2002.Effects of phorbol myristate acetate and sivelestat on the lung injury caused by fat embolism in isolated lungs.New anti-inflammatory therapies and targets for asthma and chronic obstructive pulmonary disease.Niacinamide mitigated the acute lung injury induced by phorbol myristate acetate in isolated rat's lungs.Acute lung injury and acute respiratory distress syndrome: experimental and clinical investigations.Transepithelial migration of neutrophils: mechanisms and implications for acute lung injurySuperiority of pulmonary administration of mepenzolate bromide over other routes as treatment for chronic obstructive pulmonary disease.Neutrophil elastase inhibitors: recent advances in the development of mechanism-based and nonelectrophilic inhibitors.Immune-mediated inflammation in the pathogenesis of emphysema: insights from mouse models.Compensatory lung growth after bilobectomy in emphysematous rats.Structure of the complex of porcine pancreatic elastase with a trimacrocyclic peptide inhibitor FR901451.Protease inhibitors in respiratory disease: focus on asthma and chronic obstructive pulmonary disease.alpha-1-Antitrypsin ameliorates cigarette smoke-induced emphysema in the mouse.Sulfated caffeic acid dehydropolymer attenuates elastase and cigarette smoke extract-induced emphysema in rats: sustained activity and a need of pulmonary delivery.Steroid-resistant inflammation in a rat model of chronic obstructive pulmonary disease is associated with a lack of nuclear factor-kappaB pathway activation.Pulmonary emphysema induced by methylphenidate: experimental study.Adrenomedullin regenerates alveoli and vasculature in elastase-induced pulmonary emphysema in mice.Feasibility of Computed Tomography in a Multicenter COPD Trial: A Study of the Effect of AZD9668 on Structural Airway Changes.Proteases and Their Inhibitors in Chronic Obstructive Pulmonary Disease
P2860
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P2860
A novel oral neutrophil elastase inhibitor (ONO-6818) inhibits human neutrophil elastase-induced emphysema in rats.
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年學術文章
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name
A novel oral neutrophil elasta ...... ase-induced emphysema in rats.
@en
A novel oral neutrophil elastase inhibitor
@nl
type
label
A novel oral neutrophil elasta ...... ase-induced emphysema in rats.
@en
A novel oral neutrophil elastase inhibitor
@nl
prefLabel
A novel oral neutrophil elasta ...... ase-induced emphysema in rats.
@en
A novel oral neutrophil elastase inhibitor
@nl
P2093
P356
P1476
A novel oral neutrophil elasta ...... ase-induced emphysema in rats.
@en
P2093
Masanori Takayama
Masayoshi Ishibashi
Minoru Yoshida
Motokimi Shiraishi
Takashige Kuraki
P304
P356
10.1164/RCCM.2103118
P407
P577
2002-08-01T00:00:00Z