about
In vitro and in vivo pharmacological characterization of a neuropeptide S tetrabranched derivative.Exploring pharmacological activities and signaling of morphinans substituted in position 6 as potent agonists interacting with the μ opioid receptor.Acute and chronic antiparkinsonian effects of the novel nociceptin/orphanin FQ receptor antagonist NiK-21273 in comparison with SB-612111.The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled ReceptorPharmacological characterization of tachykinin tetrabranched derivatives.In vitro and in vivo pharmacological characterization of nociceptin/orphanin FQ tetrabranched derivatives.Pharmacological investigations of N-substituent variation in morphine and oxymorphone: opioid receptor binding, signaling and antinociceptive activityPharmacological Profile of Nociceptin/Orphanin FQ Receptors Interacting with G-Proteins and β-Arrestins 2.Characterisation of the Novel Mixed Mu-NOP Peptide Ligand Dermorphin-N/OFQ (DeNo).Pharmacological characterization of cebranopadol a novel analgesic acting as mixed nociceptin/orphanin FQ and opioid receptor agonistIn vitro functional characterization of novel nociceptin/orphanin FQ receptor agonists in recombinant and native preparations.Beta-arrestin 2 rather than G protein efficacy determines the anxiolytic-versus antidepressant-like effects of nociceptin/orphanin FQ receptor ligands.Pharmacological studies on the NOP and opioid receptor agonist PWT2-[Dmt1]N/OFQ(1-13).In vitro pharmacological characterization of a novel unbiased NOP receptor-selective nonpeptide agonist AT-403.In vitro and in vivo pharmacological characterization of Pronetupitant, a prodrug of the neurokinin 1 receptor antagonist Netupitant.Heterologous Expression, Biosynthetic Studies, and Ecological Function of the Selective Gq-Signaling Inhibitor FR900359.Structure activity studies of nociceptin/orphanin FQ(1-13)-NH2 derivatives modified in position 5.Lack of beta-arrestin signaling in the absence of active G proteins.Pharmacological characterization of endomorphin-2-based cyclic pentapeptides with methylated phenylalanine residues.A novel and facile synthesis of tetra branched derivatives of nociceptin/orphanin FQ.[d-Pen(p- t BuBzl)5]NPS, a novel ligand for the neuropeptide S receptor: structure activity and pharmacological studiesNOP receptor pharmacological profile - A dynamic mass redistribution studyRational design of a heterotrimeric G protein α subunit with artificial inhibitor sensitivitySynthesis and Structure-Activity Relationships of Triazaspirodecanone Derivatives as Nociceptin/Orphanin FQ Receptor LigandsPharmacological Assays for Investigating the NOP Receptor
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description
researcher
@en
wetenschapper
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հետազոտող
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name
Davide Malfacini
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Davide Malfacini
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Davide Malfacini
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Davide Malfacini
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Davide Malfacini
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Davide Malfacini
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Davide Malfacini
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Davide Malfacini
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Davide Malfacini
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Davide Malfacini
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D Malfacini
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Davide Malfacini
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Davide Malfacini
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Davide Malfacini
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Davide Malfacini
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Davide Malfacini
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P106
P1153
55569907600
P31
P496
0000-0003-4562-9550