Model reduction in mathematical pharmacology : Integration, reduction and linking of PBPK and systems biology models.

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Model reduction in mathematical pharmacology : Integration, reduction and linking of PBPK and systems biology models.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年學術文章

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2018年學術文章

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Model reduction in mathematica ...... PK and systems biology models.

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Model reduction in mathematica ...... PK and systems biology models.

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label

Model reduction in mathematica ...... PK and systems biology models.

@en

Model reduction in mathematica ...... PK and systems biology models.

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Model reduction in mathematica ...... PK and systems biology models.

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Model reduction in mathematica ...... PK and systems biology models.

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P1476

Model reduction in mathematica ...... BPK and systems biology models

@en

P2093

Marcus J Tindall

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Piet H van der Graaf

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P2860

Systems pharmacology: network analysis to identify multiscale mechanisms of drug action

Combining the 'bottom up' and 'top down' approaches in pharmacokinetic modelling: fitting PBPK models to observed clinical data

Scale reduction of a systems coagulation model with an application to modeling pharmacokinetic-pharmacodynamic data.

A method for zooming of nonlinear models of biochemical systems.

New time-scale criteria for model simplification of bio-reaction systems

Zooming of states and parameters using a lumping approach including back-translation.

Simplification of biochemical models: a general approach based on the analysis of the impact of individual species and reactions on the systems dynamics.

Whole body pharmacokinetic models.

Predicting the F(ab)-mediated effect of monoclonal antibodies in vivo by combining cell-level kinetic and pharmacokinetic modelling

Reduced-order modelling of biochemical networks: application to the GTPase-cycle signalling module

P2888

s10928-018-9584-y

P304

537-555

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P31

scholarly article

P356

10.1007/S10928-018-9584-Y

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P433

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P478

http://www.w3.org/2001/XMLSchema#string

P50

Thomas J Snowden

P577

2018-03-26T00:00:00Z

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P698

29582349

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P932

6061126

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