miRNAs--pathway engineering of CHO cell factories that avoids translational burdening.
about
Use of a small molecule cell cycle inhibitor to control cell growth and improve specific productivity and product quality of recombinant proteins in CHO cell culturesAnalysis of microRNA transcription and post-transcriptional processing by Dicer in the context of CHO cell proliferationMiRNA mimic screen for improved expression of functional neurotensin receptor from HEK293 cellsUnveiling the principle of microRNA-mediated redundancy in cellular pathway regulationCHO microRNA engineering is growing up: recent successes and future challenges.The endoplasmic reticulum and unfolded protein response in the control of mammalian recombinant protein production.Identification of a novel miRNA that increases transient protein expression in combination with valproic acid.miRNA engineering of CHO cells facilitates production of difficult-to-express proteins and increases success in cell line development.ATF6β-based fine-tuning of the unfolded protein response enhances therapeutic antibody productivity of Chinese hamster ovary cells.Stable overexpression of miR-17 enhances recombinant protein production of CHO cells.miR-143 targets MAPK7 in CHO cells and induces a hyperproductive phenotype to enhance production of difficult-to-express proteins.A functional high-content miRNA screen identifies miR-30 family to boost recombinant protein production in CHO cells.CHO cell culture longevity and recombinant protein yield are enhanced by depletion of miR-7 activity via sponge decoy vectors.Endogenous microRNA clusters outperform chimeric sequence clusters in Chinese hamster ovary cellsConserved microRNA function as a basis for Chinese hamster ovary cell engineering.Methods for Using Small Non-Coding RNAs to Improve Recombinant Protein Expression in Mammalian Cells.Identifying HIPK1 as Target of miR-22-3p Enhancing Recombinant Protein Production From HEK 293 Cell by Using Microarray and HTP siRNA Screen.miR-CATCH Identifies Biologically Active miRNA Regulators of the Pro-Survival Gene XIAP, in Chinese Hamster Ovary Cells.Re-programming CHO cell metabolism using miR-23 tips the balance towards a highly productive phenotype.miR-2861 as novel HDAC5 inhibitor in CHO cells enhances productivity while maintaining product quality.Cell Line Techniques and Gene Editing Tools for Antibody Production: A Review.
P2860
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P2860
miRNAs--pathway engineering of CHO cell factories that avoids translational burdening.
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年學術文章
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2012年學術文章
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miRNAs--pathway engineering of CHO cell factories that avoids translational burdening.
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miRNAs--pathway engineering of CHO cell factories that avoids translational burdening.
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type
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miRNAs--pathway engineering of CHO cell factories that avoids translational burdening.
@en
miRNAs--pathway engineering of CHO cell factories that avoids translational burdening.
@nl
prefLabel
miRNAs--pathway engineering of CHO cell factories that avoids translational burdening.
@en
miRNAs--pathway engineering of CHO cell factories that avoids translational burdening.
@nl
P50
P1476
miRNAs--pathway engineering of CHO cell factories that avoids translational burdening.
@en
P304
P356
10.1016/J.TIBTECH.2012.05.002
P577
2012-06-04T00:00:00Z