about
Synthesis, absolute configuration and antimuscarinic activity of the enantiomers of [1-(2,2-diphenyl-[1,3]dioxolan-4-yl)-ethyl]-dimethyl-amine.Enigmatic receptors.Synthesis of 5-methyl-1,3-oxathiolane-based nucleoside analogues as potential antiviral agents.5-Arylbenzothiadiazine Type Compounds as Positive Allosteric Modulators of AMPA/Kainate Receptors.Alpha2-adrenoreceptors profile modulation and high antinociceptive activity of (S)-(-)-2-[1-(biphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole.2-[[[2-(2,6-Dimethoxyphenoxy)ethyl]amino]-methyl] -1,4-benzoxathian: a new antagonist with high potency and selectivity toward alpha 1-adrenoreceptors.1,3-Dioxolane-based ligands incorporating a lactam or imide moiety: structure-affinity/activity relationship at alpha1-adrenoceptor subtypes and at 5-HT1A receptors.Discovery of a new series of 5-HT1A receptor agonists.Pharmacological characterization of muscarinic receptor subtypes in rabbit isolated tissue preparations.Imidazoline binding sites (IBS) profile modulation: key role of the bridge in determining I1-IBS or I2-IBS selectivity within a series of 2-phenoxymethylimidazoline analogues.I1 imidazoline receptor-mediated effects on apoptotic processes in PC12 cells.1,2,4-Benzothiadiazine derivatives as alpha1 and 5-HT1A receptor ligands.1,3-Dioxolane-based ligands as rigid analogues of naftopidil: structure-affinity/activity relationships at alpha1 and 5-HT1A receptors.(2,2-Diphenyl-[1,3]oxathiolan-5-ylmethyl)-(3-phenyl-propyl)-amine: a potent and selective 5-HT(1A) receptor agonist.Fluoronorepinephrines: further pharmacological evaluation in vitro and in pithed rats.Synthesis and structure-activity relationship studies in a series of 2-substituted 1,3-dioxolanes modified at the cationic head.Structure-Activity Relationships within a Series of σ1 and σ2 Receptor Ligands: Identification of a σ2 Receptor Agonist (BS148) with Selective Toxicity against Metastatic Melanoma.Synthesis and antimuscarinic activity of some ether- and thioether-bearing 1,3-dioxolanes and related sulfoxides and sulfones.Further insights into the pharmacology of the human trace amine-associated receptors: discovery of novel ligands for TAAR1 by a virtual screening approach.Ligand binding to I2 imidazoline receptor: the role of lipophilicity in quantitative structure-activity relationship models.Insights into the structure and pharmacology of the human trace amine-associated receptor 1 (hTAAR1): homology modelling and docking studies.Imidazoline receptors: qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity.Development, validation and application of an LC-MS/MS bioanalytical method for the quantification of GF449, a novel 5-HT1A agonist, in rat plasma and brain.Structure-affinity/activity relationships of 1,4-dioxa-spiro[4.5]decane based ligands at α<alpha>1 and 5-HT1A receptors.Synthesis, biological evaluation, and docking studies of tetrahydrofuran- cyclopentanone- and cyclopentanol-based ligands acting at adrenergic α₁- and serotonine 5-HT1A receptors.Hypotensive effect in dogs and rats of intravenous injections of the alpha 1-adrenoreceptor antagonist benoxathian.1,3-dioxolane-based ligands as a novel class of alpha1-adrenoceptor antagonists.The XIXth National Meeting on Medicinal Chemistry: Verona, Italy.Structure-activity relationships in prazosin-related compounds. Effect of replacing a piperazine ring with an alkanediamine moiety on alpha 1-adrenoreceptor blocking activity.Synthesis and Ca-antagonist activity of some benzhydryl derivatives.Diastereoselective Synthesis of (1,3-Dioxan-4-yl)pyrimidine and Purin Nucleoside AnaloguesAlpha2-Adrenergic Receptors in Intestinal Epithelial Cells: Mechanisms of Signaling, Role, and RegulationAn Unexpected Central Hypertensive Effect of the New Imidazoline Compound BenazolineBinding of Tracizolines to the Imidazoline Receptor: Role of Lipophilicity in Quantitative Structure-Activity Relationship ModelsaSynthesis, NMR spectroscopy study, and antimuscarinic activity of a series of 2-(Acyloxymethyl)-1,3-dioxolanesA New and Versatile Synthesis of 1,3-Dioxan-5-yl-pyrimidine and Purine Nucleoside AnaloguesTransacetalization of Acetals with Butane-1,2,4-triol Using Cobalt(II) Chloride and ChlorotrimethylsilaneStructure–activity relationship at α-adrenergic receptors within a series of imidazoline analogues of cirazolineSynthesis and pharmacological evaluation of some analogues of the Ca-antagonist cinnarizineStructure-activity relationships for prazosin and WB 4101 analogues as alpha 1-adrenoreceptor antagonists
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Q32020805-863343E5-923D-42B3-A37B-2407DE1EF010Q33919831-0908C2EE-9879-4D44-AAA1-69ACCF6D923AQ39323580-E69A4AF8-3A8D-433A-B206-449A755BABFBQ39730613-7EC55972-B74B-41C1-8BCA-692F7FE36F7FQ40761171-6365AE70-A19F-42E9-AEAA-1FBCE56B3788Q42242535-39B99CBA-AE41-4A41-BAD4-8891B8522229Q42982831-A51F0845-C039-4A6A-95EA-263CD1B0C9E9Q43149191-88A91A46-9754-4774-8A33-61476E170E95Q43579029-0F7FE199-1D51-49D8-BD9D-B421AE949FF7Q44441542-A2DF13FD-B679-4766-BE09-B2979ABF07CBQ44895991-BEA79049-D907-4438-BE0A-8FEDF1307247Q45248317-45597957-0403-4A1B-9BE5-787A52E42FCCQ46157845-41264061-1BAA-4C97-BB5C-A8D417F94C20Q46186696-36AF13BA-DF1B-49F3-89F6-874DD83964C6Q46324760-3EFB0300-F524-4DD2-AD83-3ACF0F2B5C4CQ46754894-64D59B3C-9097-4B94-BFC5-611066B6C117Q47756273-981762D9-83C9-48B4-8A94-A175B4DB4E47Q47779138-99839295-D4AC-4B7D-8262-87718D0EE4B7Q48281018-4F5C3442-18C3-4EA8-8D54-D65F4B49FED5Q48296707-DD5118F4-A705-4AE8-B578-2442688D9A5AQ48413428-390C95C9-58B8-4B8C-B1EF-267F14B7BA4DQ48711585-0E4B3AD6-DF39-4AB7-ABFC-9C332993F706Q48837667-F2A23F13-DBA7-4EC5-9EC9-5B58F1E4D73DQ51049557-BB60ADE5-84EE-45A7-B5E5-6118C30C6C62Q51763201-5498DEDF-4693-4686-A5E7-17FC9961DE08Q51804579-AF465F72-5558-490F-B1F2-9224FB8D0F43Q51838385-CCCBC28E-BF54-43A7-82B3-7E133C07D942Q53193782-983B35CF-0AFC-42A0-861B-8E50BB900CF9Q54430463-97D66726-53A4-4973-87E2-249F4BA540E7Q54721965-4463464E-0CDF-48B1-A96E-64DAF6E66C78Q56763260-817C9166-F75C-4A8B-A3F8-46E658207FA0Q56986631-CCFB8540-8946-4E5C-B135-CC2D732FB171Q59588209-6EFEAC6D-779F-4C25-949C-AAB7C3D87828Q59588557-13E2BE2B-341A-48BA-9D1C-3D6737C968F7Q62097100-ED7FDAB2-0A5D-4BDC-B445-C10D3D6EAB32Q62590311-6B521B1F-CB4B-4859-BE74-A2F2C20FBC0EQ62590314-99DB179A-9807-44CD-BA57-97A772F11519Q62590319-6723E1E9-2FE7-427C-B96C-9FDDDEA87276Q68430608-7DD5B98E-D4B2-4095-B11D-46A916DAB6CFQ69868623-6AC6F2CB-85A0-4904-AB8E-7E8B1BA11BF7
P50
description
onderzoeker
@nl
researcher
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հետազոտող
@hy
name
Livio Brasili
@ast
Livio Brasili
@en
Livio Brasili
@es
Livio Brasili
@nl
Livio Brasili
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type
label
Livio Brasili
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Livio Brasili
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Livio Brasili
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Livio Brasili
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Livio Brasili
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Livio Brasili
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Livio Brasili
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Livio Brasili
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Livio Brasili
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Livio Brasili
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P1053
D-7620-2015
P106
P1153
7003406114
P31
P3829
P496
0000-0002-3280-3196