Delta-like 4 Notch ligand regulates tumor angiogenesis, improves tumor vascular function, and promotes tumor growth in vivo.
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Notch signaling in prostate cancer: refining a therapeutic opportunityNotch signaling deregulation in multiple myeloma: A rational molecular targetOverview of Methods for Overcoming Hindrance to Drug Delivery to Tumors, with Special Attention to Tumor Interstitial FluidMechanisms of neovascularization and resistance to anti-angiogenic therapies in glioblastoma multiformeTips, stalks, tubes: notch-mediated cell fate determination and mechanisms of tubulogenesis during angiogenesisBroad targeting of angiogenesis for cancer prevention and therapyBrain tumor stem cells: Molecular characteristics and their impact on therapyEscaping Antiangiogenic Therapy: Strategies Employed by Cancer CellsEpsin Family of Endocytic Adaptor Proteins as Oncogenic Regulators of Cancer ProgressionFlt-1 (VEGFR-1) coordinates discrete stages of blood vessel formationNotch inhibition as a promising new approach to cancer therapy.Vascular endothelial growth factor as an anti-angiogenic target for cancer therapyPreclinical molecular imaging of tumor angiogenesis.Endothelial Notch4 signaling induces hallmarks of brain arteriovenous malformations in mice.Constitutively active endothelial Notch4 causes lung arteriovenous shunts in mice.Inhibition of delta-like-4-mediated signaling impairs reparative angiogenesis after ischemia.Effects of acute versus chronic hypoxia on DNA damage responses and genomic instability.Delta-like ligand 4 plays a critical role in pericyte/vascular smooth muscle cell formation during vasculogenesis and tumor vessel expansion in Ewing's sarcoma.Notch signalling in ischaemia-induced angiogenesis.Involvement of the Reck tumor suppressor protein in maternal and embryonic vascular remodeling in miceNotch regulates the angiogenic response via induction of VEGFR-1.Spatially addressed combinatorial protein libraries for recombinant antibody discovery and optimization.PET Imaging of Dll4 Expression in Glioblastoma and Colorectal Cancer Xenografts Using (64)Cu-Labeled Monoclonal Antibody 61BExpression of vascular notch ligand delta-like 4 and inflammatory markers in breast cancerDifferential expression of the Notch1 receptor, and its ligands Dll1, Dll3 and Dll4 in distinct human pituitary adenoma subtypes.Delta-like ligand 4 (Dll4) predicts the prognosis of clear cell renal cell carcinoma, and anti-Dll4 suppresses tumor growth in vivo.LC3A-positive light microscopy detected patterns of autophagy and prognosis in operable breast carcinomas.Vascular Mimicry: A Novel Neovascularization Mechanism Driving Anti-Angiogenic Therapy (AAT) Resistance in GlioblastomaInhibition of Notch signaling alters the phenotype of orthotopic tumors formed from glioblastoma multiforme neurosphere cells but does not hamper intracranial tumor growth regardless of endogene Notch pathway signaturePotential therapeutic implications of cancer stem cells in glioblastomaThe antiangiogenic 16K prolactin impairs functional tumor neovascularization by inhibiting vessel maturation.The functional role of Notch signaling in human gliomas.Therapy targets in glioblastoma and cancer stem cells: lessons from haematopoietic neoplasms.Imaging hypoxia in gliomas.Up-regulation of PIK3CA promotes metastasis in gastric carcinoma.Xiaotan Sanjie decoction attenuates tumor angiogenesis by manipulating Notch-1-regulated proliferation of gastric cancer stem-like cells.The characteristics of bone marrow-derived endothelial progenitor cells and their effect on glioma.Notch signaling in serous ovarian cancer.Angiopoietin-1/Tie2 signal augments basal Notch signal controlling vascular quiescence by inducing delta-like 4 expression through AKT-mediated activation of beta-cateninAnti-angiogenic effect of the total flavonoids in Scutellaria barbata D. Don
P2860
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P2860
Delta-like 4 Notch ligand regulates tumor angiogenesis, improves tumor vascular function, and promotes tumor growth in vivo.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Delta-like 4 Notch ligand regu ...... promotes tumor growth in vivo.
@en
Delta-like 4 Notch ligand regu ...... promotes tumor growth in vivo.
@nl
type
label
Delta-like 4 Notch ligand regu ...... promotes tumor growth in vivo.
@en
Delta-like 4 Notch ligand regu ...... promotes tumor growth in vivo.
@nl
prefLabel
Delta-like 4 Notch ligand regu ...... promotes tumor growth in vivo.
@en
Delta-like 4 Notch ligand regu ...... promotes tumor growth in vivo.
@nl
P2093
P50
P1433
P1476
Delta-like 4 Notch ligand regu ...... promotes tumor growth in vivo
@en
P2093
Helen Turley
Ji-Liang Li
Johannes A Hainfellner
Laura S Harrington
Richard C A Sainson
Russell Leek
Swethajit Biswas
P304
11244-11253
P356
10.1158/0008-5472.CAN-07-0969
P407
P577
2007-12-01T00:00:00Z