Predicting mutation outcome from early stochastic variation in genetic interaction partners.
about
The histone demethylase Jarid1b ensures faithful mouse development by protecting developmental genes from aberrant H3K4me3Molecular mechanisms of robustness in plantsBeyond genotype to phenotype: why the phenotype of an individual cannot always be predicted from their genome sequence and the environment that they experienceA guide for functional analysis of BRCA1 variants of uncertain significanceInterplay between gene expression noise and regulatory network architectureNetwork medicine approaches to the genetics of complex diseasesDosage compensation of the sex chromosomesDifferent levels of catabolite repression optimize growth in stable and variable environmentsThe maternal-to-zygotic transition targets actin to promote robustness during morphogenesisRNA chaperones buffer deleterious mutations in E. coli.The molecular chaperone DnaK is a source of mutational robustnessEstimating the rate of irreversibility in protein evolution.Turning randomness into meaning at the molecular level using Muller's morphs.The background puzzle: how identical mutations in the same gene lead to different disease symptoms.Gene expression in teratogenic exposures: a new approach to understanding individual risk.Pitfalls of predicting complex traits from SNPs.Deficient Vitamin E Uptake During Development Impairs Neural Tube Closure in Mice Lacking Lipoprotein Receptor SR-BI.Transposons, environmental changes, and heritable induced phenotypic variability.RETRACTED: Predicting new molecular targets for rhein using network pharmacology.Human monogenic disease genes have frequently functionally redundant paralogs.Hypothesis-based analysis of gene-gene interactions and risk of myocardial infarction.Lessons from model organisms: phenotypic robustness and missing heritability in complex disease.Hsp90 promotes kinase evolutionPredicting functional and regulatory divergence of a drug resistance transporter gene in the human malaria parasiteSemi-quantitative monitoring of confluence of adherent mesenchymal stromal cells on calcium-phosphate granules by using widefield microscopy images.The unfolded protein response is required for dendrite morphogenesis.Negative feedback confers mutational robustness in yeast transcription factor regulationStructural and Functional Recovery of Sensory Cilia in C. elegans IFT Mutants upon Aging.Cryptic genetic variation: evolution's hidden substrateEpigenetic epistatic interactions constrain the evolution of gene expression.The protein chaperone HSP90 can facilitate the divergence of gene duplicatesGenetic variants and their interactions in disease risk prediction - machine learning and network perspectivesComplex expression dynamics and robustness in C. elegans insulin networks.Phenotypic plasticity in nematodes: Evolutionary and ecological significanceWhat's Luck Got to Do with It: Single Cells, Multiple Fates, and Biological Nondeterminism.Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network.High-throughput discovery of novel developmental phenotypes.Chromatin regulators, phenotypic robustness, and autism risk.Mechanisms of transcriptional precision in animal development.Understanding multimodal biological decisions from single cell and population dynamics.
P2860
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P2860
Predicting mutation outcome from early stochastic variation in genetic interaction partners.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh-hant
name
Predicting mutation outcome fr ...... genetic interaction partners.
@en
Predicting mutation outcome fr ...... genetic interaction partners.
@nl
type
label
Predicting mutation outcome fr ...... genetic interaction partners.
@en
Predicting mutation outcome fr ...... genetic interaction partners.
@nl
prefLabel
Predicting mutation outcome fr ...... genetic interaction partners.
@en
Predicting mutation outcome fr ...... genetic interaction partners.
@nl
P2860
P356
P1433
P1476
Predicting mutation outcome fr ...... genetic interaction partners.
@en
P2093
Alejandro Burga
M Olivia Casanueva
P2860
P2888
P304
P356
10.1038/NATURE10665
P407
P50
P577
2011-12-07T00:00:00Z
P5875
P6179
1045039966