Targeting the p53 pathway to protect the neonatal ischemic brain. - Wikidata - awgldk - TriplyDB

Targeting the p53 pathway to protect the neonatal ischemic brain.

Targeting the p53 pathway to protect the neonatal ischemic brain.

http://www.wikidata.org/entity/Q51864096

about

Oxidative stress, DNA damage, and the telomeric complex as therapeutic targets in acute neurodegeneration Mechanisms of chemotherapy-induced behavioral toxicities Role of mitochondria in apoptotic and necroptotic cell death in the developing brain Drp1 stabilizes p53 on the mitochondria to trigger necrosis under oxidative stress conditions in vitro and in vivo Effects of oxygen-glucose deprivation on microglial mobility and viability in developing mouse hippocampal tissues.Inhibition of Mitochondrial p53 Accumulation by PFT-μ Prevents Cisplatin-Induced Peripheral Neuropathy.p53 and mitochondrial function in neurons.Inhibition of mitochondrial p53 abolishes the detrimental effects of social isolation on ischemic brain injury Intrauterine ischemic reperfusion switches the fetal transcriptional pattern from HIF-1α- to P53-dependent regulation in the murine brain XingNaoJing, prescription of traditional Chinese medicine, prevents autophagy in experimental stroke by repressing p53-DRAM pathway.Programmed Necrosis: A Prominent Mechanism of Cell Death following Neonatal Brain Injury Mitochondrial Optic Atrophy (OPA) 1 Processing Is Altered in Response to Neonatal Hypoxic-Ischemic Brain Injury.The role of inflammation in perinatal brain injury.Cyclosporine A Suppressed Glucose Oxidase Induced P53 Mitochondrial Translocation and Hepatic Cell Apoptosis through Blocking Mitochondrial Permeability Transition.Prevention of chemotherapy-induced peripheral neuropathy by the small-molecule inhibitor pifithrin-μ.Perinatal brain damage: The term infant.Forebrain neuronal specific ablation of p53 gene provides protection in a cortical ischemic stroke model.The rodent endovascular puncture model of subarachnoid hemorrhage: mechanisms of brain damage and therapeutic strategies.Effect of Trp53 gene deficiency on brain injury after neonatal hypoxia-ischemia Mitochondria and perinatal brain injury.Molecular mechanisms of neonatal brain injury.The endogenous regenerative capacity of the damaged newborn brain: boosting neurogenesis with mesenchymal stem cell treatment.Oxygen regulates molecular mechanisms of cancer progression and metastasis.The mechanisms and treatment of asphyxial encephalopathy.Dynamic Monitoring of p53 Translocation to Mitochondria for the Analysis of Specific Inhibitors Using Luciferase-fragment Complementation.Mitochondrial death functions of p53.Pifithrin-α provides neuroprotective effects at the level of mitochondria independently of p53 inhibition.Mechanisms of Neurotoxic Symptoms as a Result of Breast Cancer and Its Treatment: Considerations on the Contribution of Stress, Inflammation, and Cellular Bioenergetics Post-traumatic administration of the p53 inactivator pifithrin-α oxygen analogue reduces hippocampal neuronal loss and improves cognitive deficits after experimental traumatic brain injury.Prevention of neonatal oxygen-induced brain damage by reduction of intrinsic apoptosis.Mitochondria, Bioenergetics and Excitotoxicity: New Therapeutic Targets in Perinatal Brain Injury Haploinsufficiency in the mitochondrial protein CHCHD4 reduces brain injury in a mouse model of neonatal hypoxia-ischemia.Cell Death in the Developing Brain after Hypoxia-Ischemia Oxidative stress and endoplasmic reticulum (ER) stress in the development of neonatal hypoxic-ischaemic brain injury.Role of Perinatal Inflammation in Neonatal Arterial Ischemic Stroke.Piracetam ameliorated oxygen and glucose deprivation-induced injury in rat cortical neurons via inhibition of oxidative stress, excitatory amino acids release and P53/Bax.Safety and Tolerability Study of an Intravenously Administered Small Interfering Ribonucleic Acid (siRNA) Post On-Pump Cardiothoracic Surgery in Patients at Risk of Acute Kidney Injury.Mitochondrial dynamics, mitophagy and biogenesis in neonatal hypoxic-ischaemic brain injury.Pifithrin-μ Prevents Cisplatin-Induced Chemobrain by Preserving Neuronal Mitochondrial Function.Neuroprotective effects of pifithrin-α against traumatic brain injury in the striatum through suppression of neuroinflammation, oxidative stress, autophagy, and apoptosis.

P2860

Q26995219-D8D2C84E-7D45-4922-89F8-1BFCB0894D1A Q26998870-BE67F84C-97EF-401D-A921-5F2D9BA291C9 Q28083288-04037749-92EC-43BC-BC4A-DDCB5574E7A7 Q28238683-DE5E479A-0319-44AC-B5A1-DDC9891E303D Q30547682-48E21C76-56DE-4438-B6C8-14FF7F6E30FB Q33571709-1F5F9696-F766-4748-B517-DE819C8AE754 Q33819250-651105F4-EA81-41DC-9279-BC1A6D867FB4 Q34317907-F2A4DF1B-0517-41AA-B132-0073D69F5CB8 Q34362232-CAD77725-F481-4961-9CE1-3EA45E28A527 Q35813245-0C9A698F-9FE7-46EA-84BA-0D65F75C39A6 Q35994637-CE8567EF-B63E-4E90-A7E3-C8FCA8510218 Q36184255-FFFE07A8-0B50-40CE-AEAA-6E20CA3730A8 Q36331560-52B2CA1F-F687-4794-BE85-0EC96ABF4FC4 Q36534051-DCC4A66F-458A-4A3E-A059-5A949111584D Q36988206-2A204C4A-6171-426E-A35A-76B3FDE5EDCD Q37025326-FFCA90B1-8AB3-4616-86A3-75EA8068C457 Q37137634-FAA417EC-C05F-4F30-944A-F489D216518A Q37479890-DAF19CC2-D8C4-4276-AECA-B707DE8ED426 Q37707049-CE32EC81-D9ED-4D4C-A6D1-70819017105E Q37986198-D5C730E6-8580-405F-98AB-ECB4FFBA0F78 Q37987945-669E0009-EC84-4513-ABD3-69AA313A76DE Q38081017-2422A182-5A31-4C15-888E-254DA9A1AB42 Q38171333-1EA58CFB-EF36-4CBC-AC71-85AC8FB6D17F Q38191905-442D05DC-08FF-4AA7-BAFB-FC84E5947E15 Q38612375-2963CBE3-F3D4-49A6-8CD6-7307ABAE4958 Q38866668-00A4C270-AA2F-4A8A-9232-8ABFC86CB8BF Q38945300-B010F910-EB6B-4C32-AB48-4B172AEA2B6C Q39374624-BD27592C-21B4-4619-BF13-6117549493A7 Q39461208-07DAA7DB-F0E4-485F-8E59-DF34D449A523 Q40787523-251FC814-C890-44A4-BAE7-C066B29EF883 Q40987303-F7E0ABAF-AC3C-4000-88CD-72AC8AD1E22B Q41082627-2DA6AD32-C6B4-44BD-AB64-B4486C5280F1 Q41526704-49A6F58D-F258-4945-A243-EEA86F2E712A Q42650888-0E00B587-778D-491F-B673-E23016BC9822 Q46642629-3C84043B-240D-40A5-B0CA-2EB10F49C8FF Q46927400-0D34868E-B803-4462-9F70-B7F14EBBBABA Q47099409-2ACA0792-F32B-4FB5-B568-E65094B8BFC7 Q47229517-3B3F813E-FC9D-49F1-B11D-99D381D0E7F3 Q48419384-542D64C5-5A5A-4535-BAB7-34F557088D6B Q49771217-1E357DE1-6FAC-44C9-8AC3-7D9BE8EC08A4

P2860

Targeting the p53 pathway to protect the neonatal ischemic brain.

http://www.wikidata.org/entity/Q51864096

description

2011 nî lūn-bûn

@nan

2011年の論文

@ja

2011年学术文章

@wuu

2011年学术文章

@zh

2011年学术文章

@zh-cn

2011年学术文章

@zh-hans

2011年学术文章

@zh-my

2011年学术文章

@zh-sg

2011年學術文章

@yue

2011年學術文章

@zh-hant

name

Targeting the p53 pathway to protect the neonatal ischemic brain.

@en

Targeting the p53 pathway to protect the neonatal ischemic brain.

@nl

type

label

Targeting the p53 pathway to protect the neonatal ischemic brain.

@en

Targeting the p53 pathway to protect the neonatal ischemic brain.

@nl

prefLabel

Targeting the p53 pathway to protect the neonatal ischemic brain.

@en

Targeting the p53 pathway to protect the neonatal ischemic brain.

@nl

P1433

Q51864096-BC8B72BA-B0B3-4751-B4B5-F4203A340588

P1476

Q51864096-44553157-BBE0-4A31-9E65-3E1E6594EBDC

P2093

Q51864096-041F4678-9658-4752-B291-124D4561DB94

Q51864096-442F9C80-C215-41AF-8CDD-8D5DD2E5B267

Q51864096-65A0B626-5F96-41E5-8AEA-EF63BB1151AD

Q51864096-87F84669-2836-47A7-B910-7AF2C651F34D

Q51864096-E597C709-2BD4-442B-9A43-854B1FA0EFF2

P2860

Q51864096-10676474-9975-4408-A72F-4B73986B345E

Q51864096-12387D7E-CA5A-4817-BB12-26E85E50F352

Q51864096-189EDFB8-F8F6-4EE2-B712-8BC951CB5E90

Q51864096-1974D2D1-136E-443D-A6B6-F18AD7EED5E0

Q51864096-1A57811A-1F71-4854-A680-61E4109C0BD9

Q51864096-1D7D6BD7-74C5-4756-9987-375426E15456

Q51864096-24A7B5C0-A186-4A85-899D-365D7DEB77FB

Q51864096-2A4396A5-5A7F-4A80-BAA1-5DB13218076A

Q51864096-2BC1A6F9-F888-4178-999E-3FED3A6926BD

Q51864096-31E981DD-1EBC-4191-B43C-5590C1159177

P304

Q51864096-79147EB9-3081-4FDF-99B2-9A5A581235B8

P31

Q51864096-C1E8B969-C02A-4D32-8DAF-ED2B72521B5D

P356

Q51864096-68D9DB90-E9CF-4F95-900B-384FBE0F8DE9

P433

Q51864096-160E05B4-7A62-415F-8C8E-44D5D771BD65

P478

Q51864096-1CAA2141-FF9F-4EF3-84FA-C89C0CF4069C

P50

Q51864096-2EB86604-AC70-4BD9-9B8B-2D146DA7BC30

Q51864096-37A688B7-FA95-41D6-A3EB-CEC149D26FB7

Q51864096-44B4E6F8-F253-4488-BFD0-24A43D8188EC

Q51864096-46363C6F-74AA-4CC5-A04D-1BC1C4086E20

P577

Q51864096-1BF9A32C-AACE-46E7-9A1F-59DBE89D5380

P5875

Q51864096-5CE9CD5F-D0DB-4717-B22B-10C2BC7F5206

P698

Q51864096-B80C6AEF-041A-48FF-8981-E0D888E8B90E

P356

P1433

Annals of Neurology

P1476

Targeting the p53 pathway to protect the neonatal ischemic brain

@en

P2093

Annemieke Kavelaars

http://www.w3.org/2001/XMLSchema#string

Cobi J Heijnen

http://www.w3.org/2001/XMLSchema#string

Cora H Nijboer

http://www.w3.org/2001/XMLSchema#string

Frank van Bel

http://www.w3.org/2001/XMLSchema#string

Jitske Zijlstra

http://www.w3.org/2001/XMLSchema#string

P2860

p53 has a direct apoptogenic role at the mitochondria

Live or let die: the cell's response to p53

Perinatal brain injury: from pathogenesis to neuroprotection.

BclxL changes conformation upon binding to wild-type but not mutant p53 DNA binding domain.

Synergistic neuroprotective therapies with hypothermia.

Neurodegenerative disorders and ischemic brain diseases.

p53's believe it or not: lessons on transcription-independent death.

In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation

Toxic proteins released from mitochondria in cell death.

p53 in neuronal apoptosis.

P304

255-264

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1002/ANA.22413

http://www.w3.org/2001/XMLSchema#string

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

70

http://www.w3.org/2001/XMLSchema#string

P50

Michael Van Der Kooij

Carsten Culmsee

Cindy van Velthoven

P577

2011-06-14T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51220555

http://www.w3.org/2001/XMLSchema#string

P698

21674585

http://www.w3.org/2001/XMLSchema#string