UPD1p indicates the presence of MPL W515L mutation in RARS-T, a mechanism analogous to UPD9p and JAK2 V617F mutation.
about
Novel mutations and their functional and clinical relevance in myeloproliferative neoplasms: JAK2, MPL, TET2, ASXL1, CBL, IDH and IKZF1Mutations of an E3 ubiquitin ligase c-Cbl but not TET2 mutations are pathogenic in juvenile myelomonocytic leukemia.Association between acquired uniparental disomy and homozygous mutations and HER2/ER/PR status in breast cancerCopy neutral loss of heterozygosity: a novel chromosomal lesion in myeloid malignanciesLoss of wild-type Jak2 allele enhances myeloid cell expansion and accelerates myelofibrosis in Jak2V617F knock-in miceSoft tissue sarcoma subtypes exhibit distinct patterns of acquired uniparental disomy.Mutations of e3 ubiquitin ligase cbl family members constitute a novel common pathogenic lesion in myeloid malignancies.Prognostic impact of SNP array karyotyping in myelodysplastic syndromes and related myeloid malignanciesComplex patterns of chromosome 11 aberrations in myeloid malignancies target CBL, MLL, DDB1 and LMO2.CBL, CBLB, TET2, ASXL1, and IDH1/2 mutations and additional chromosomal aberrations constitute molecular events in chronic myelogenous leukemia.Clinical features and course of refractory anemia with ring sideroblasts associated with marked thrombocytosis.Different mutations of the human c-mpl gene indicate distinct haematopoietic diseasesAcquired copy-neutral loss of heterozygosity of chromosome 1p as a molecular event associated with marrow fibrosis in MPL-mutated myeloproliferative neoplasmsLoss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasmsMolecular drug targets in myeloproliferative neoplasms: mutant ABL1, JAK2, MPL, KIT, PDGFRA, PDGFRB and FGFR1.Pathogenesis and consequences of uniparental disomy in cancer.Genetic and epigenetic alterations of myeloproliferative disorders.Molecular pathogenesis of atypical CML, CMML and MDS/MPN-unclassifiable.Prognosis of Primary Myelofibrosis in the Genomic EraMolecular mechanisms associated with leukemic transformation of MPL-mutant myeloproliferative neoplasms.Spectrum of mutations in RARS-T patients includes TET2 and ASXL1 mutationsMutations of JAK2 and TET2, but not CBL are detectable in a high portion of patients with refractory anemia with ring sideroblasts and thrombocytosis.
P2860
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P2860
UPD1p indicates the presence of MPL W515L mutation in RARS-T, a mechanism analogous to UPD9p and JAK2 V617F mutation.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
UPD1p indicates the presence o ...... UPD9p and JAK2 V617F mutation.
@en
UPD1p indicates the presence o ...... UPD9p and JAK2 V617F mutation.
@nl
type
label
UPD1p indicates the presence o ...... UPD9p and JAK2 V617F mutation.
@en
UPD1p indicates the presence o ...... UPD9p and JAK2 V617F mutation.
@nl
prefLabel
UPD1p indicates the presence o ...... UPD9p and JAK2 V617F mutation.
@en
UPD1p indicates the presence o ...... UPD9p and JAK2 V617F mutation.
@nl
P2093
P2860
P356
P1433
P1476
UPD1p indicates the presence o ...... UPD9p and JAK2 V617F mutation.
@en
P2093
P2860
P2888
P304
P356
10.1038/LEU.2008.249
P577
2008-09-25T00:00:00Z