Reconstitution of a functional acetylcholine receptor. Conservation of the conformational and allosteric transitions and recovery of the permeability response; role of lipids.
about
Anesthetics target interfacial transmembrane sites in nicotinic acetylcholine receptorsTransmembrane topography of the nicotinic acetylcholine receptor delta subunit.High affinity binding of alpha-bungarotoxin to the purified alpha-subunit and to its 27,000-dalton proteolytic peptide from Torpedo marmorata acetylcholine receptor. Requirement for sodium dodecyl sulfate.Consequences of alkaline treatment for the ultrastructure of the acetylcholine-receptor-rich membranes from Torpedo marmorata electric organ.Structural sensitivity of a prokaryotic pentameric ligand-gated ion channel to its membrane environment.Complete mRNA coding sequence of the acetylcholine binding alpha-subunit of Torpedo marmorata acetylcholine receptor: a model for the transmembrane organization of the polypeptide chain.Crystal structure and dynamics of a lipid-induced potential desensitized-state of a pentameric ligand-gated channel.The lipid environment of the nicotinic acetylcholine receptor in native and reconstituted membranes.Molecular mechanisms of acetylcholine receptor-lipid interactions: from model membranes to human biology.Cations mediate interactions between the nicotinic acetylcholine receptor and anionic lipids.Intramembrane aromatic interactions influence the lipid sensitivities of pentameric ligand-gated ion channels.Structural basis for allosteric coupling at the membrane-protein interface in Gloeobacter violaceus ligand-gated ion channel (GLIC).A lipid-dependent uncoupled conformation of the acetylcholine receptorA distinct mechanism for activating uncoupled nicotinic acetylcholine receptors.Allosteric transitions of Torpedo acetylcholine receptor in lipids, detergent and amphipols: molecular interactions vs. physical constraints.Analysis of alpha-bungarotoxin binding in the goldfish central nervous system.Stabilization of the high affinity state of the membrane-bound acetylcholine receptor from Torpedo marmorata by noncompetitive-blockers. Evidence for dual interaction and pharmacological selectivity.An allosteric link connecting the lipid-protein interface to the gating of the nicotinic acetylcholine receptor.
P2860
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P2860
Reconstitution of a functional acetylcholine receptor. Conservation of the conformational and allosteric transitions and recovery of the permeability response; role of lipids.
description
1980 nî lūn-bûn
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1980年の論文
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1980年学术文章
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1980年学术文章
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1980年学术文章
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1980年学术文章
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1980年学术文章
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1980年学术文章
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1980年學術文章
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1980年學術文章
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name
Reconstitution of a functional ...... lity response; role of lipids.
@en
Reconstitution of a functional ...... lity response; role of lipids.
@nl
type
label
Reconstitution of a functional ...... lity response; role of lipids.
@en
Reconstitution of a functional ...... lity response; role of lipids.
@nl
prefLabel
Reconstitution of a functional ...... lity response; role of lipids.
@en
Reconstitution of a functional ...... lity response; role of lipids.
@nl
P2093
P2860
P1433
P1476
Reconstitution of a functional ...... lity response; role of lipids.
@en
P2093
P2860
P356
10.1111/J.1432-1033.1980.TB04839.X
P407
P577
1980-09-01T00:00:00Z