Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells.
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Therapeutic strategies for the clinical blockade of IL-6/gp130 signalingInterleukin-6 in Allogeneic Stem Cell Transplantation: Its Possible Importance for Immunoregulation and As a Therapeutic Target.Leucine-rich alpha 2 glycoprotein promotes Th17 differentiation and collagen-induced arthritis in mice through enhancement of TGF-β-Smad2 signaling in naïve helper T cells.n-3 PUFAs reduce T-helper 17 cell differentiation by decreasing responsiveness to interleukin-6 in isolated mouse splenic CD4⁺ T cells.Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environmentAltered CD8(+) T cell frequency and function in tuberculous lymphadenitis.Receptor revision in CD4 T cells is influenced by follicular helper T cell formation and germinal-center interactions.Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation.IL-6 receptor α defines effector memory CD8+ T cells producing Th2 cytokines and expanding in asthmaIncreased CD40+ Fibrocytes in Patients With Idiopathic Orbital Inflammation.Obesity Is a Positive Modulator of IL-6R and IL-6 Expression in the Subcutaneous Adipose Tissue: Significance for Metabolic InflammationPeptidylarginine deiminase type 4 deficiency reduced arthritis severity in a glucose-6-phosphate isomerase-induced arthritis model.Cellular and humoral mechanisms involved in the control of tuberculosisLong-term lung transplantation in nonhuman primates.Innate Immune Responses after Airway Epithelial Stimulation with Mycobacterium bovis Bacille-Calmette Guérin.Role of IL-6 in asthma and other inflammatory pulmonary diseases.IL-6-driven STAT signalling in circulating CD4+ lymphocytes is a marker for early anticitrullinated peptide antibody-negative rheumatoid arthritis.Novel genetically-humanized mouse model established to evaluate efficacy of therapeutic agents to human interleukin-6 receptor.Plasticity within the αβ⁺CD4⁺ T-cell lineage: when, how and what for?Identification of STOML2 as a putative novel asthma risk gene associated with IL6R.Programmed cell death 1 inhibits inflammatory helper T-cell development through controlling the innate immune response.Interleukin-6 limits influenza-induced inflammation and protects against fatal lung pathology.Interleukin-6 signaling drives fibrosis in unresolved inflammation.Histone deacetylase inhibitors modulate interleukin 6-dependent CD4+ T cell polarization in vitro and in vivoDendritic cell MST1 inhibits Th17 differentiation.Th17 cell, the new player of neuroinflammatory process in multiple sclerosis.Role of innate cytokines in mycobacterial infection.Hitting a complex target: an update on interleukin-6 trans-signalling.IL-6 trans-signaling via the soluble IL-6 receptor: importance for the pro-inflammatory activities of IL-6.Targeting classical IL-6 signalling or IL-6 trans-signalling in depression?Interleukin-6 in renal disease and therapy.Omega-3 fatty acids, lipid rafts, and T cell signalingCD4+ Group 1 Innate Lymphoid Cells (ILC) Form a Functionally Distinct ILC Subset That Is Increased in Systemic Sclerosis.Selected cytokine pathways in rheumatoid arthritis.Immune-mediated mechanisms of atherosclerosis and implications for the clinic.The role of interleukin-6 signalling and its therapeutic blockage in skewing the T cell balance in rheumatoid arthritis.Allergen-Induced IL-6 Regulates IL-9/IL-17A Balance in CD4+ T Cells in Allergic Airway Inflammation.Inhibition of classic signaling is a novel function of soluble glycoprotein 130 (sgp130), which is controlled by the ratio of interleukin 6 and soluble interleukin 6 receptorRegulation of soluble interleukin-6 (IL-6) receptor release from corneal epithelial cells and its role in the ocular surface.The Role of Proinflammatory Pathways in the Pathogenesis of Colitis-Associated Colorectal Cancer.
P2860
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P2860
Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh-hant
name
Loss of CD4+ T cell IL-6R expr ...... cal maintenance of Th17 cells.
@en
Loss of CD4+ T cell IL-6R expr ...... cal maintenance of Th17 cells.
@nl
type
label
Loss of CD4+ T cell IL-6R expr ...... cal maintenance of Th17 cells.
@en
Loss of CD4+ T cell IL-6R expr ...... cal maintenance of Th17 cells.
@nl
prefLabel
Loss of CD4+ T cell IL-6R expr ...... cal maintenance of Th17 cells.
@en
Loss of CD4+ T cell IL-6R expr ...... cal maintenance of Th17 cells.
@nl
P2093
P50
P356
P1476
Loss of CD4+ T cell IL-6R expr ...... cal maintenance of Th17 cells.
@en
P2093
Anwen S Williams
Clare R Parker
John D Williams
Jürgen Scheller
Nicholas Topley
Raj Malhotra
Victoria J Hammond
P304
P356
10.4049/JIMMUNOL.0901528
P407
P577
2010-01-18T00:00:00Z