Selective blockade of the orexin-2 receptor attenuates ethanol self-administration, place preference, and reinstatement. - Wikidata - awgldk - TriplyDB

Selective blockade of the orexin-2 receptor attenuates ethanol self-administration, place preference, and reinstatement.

Selective blockade of the orexin-2 receptor attenuates ethanol self-administration, place preference, and reinstatement.

http://www.wikidata.org/entity/Q51892779

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The hypocretin/orexin system in sleep disorders: preclinical insights and clinical progress Understanding how discrete populations of hypothalamic neurons orchestrate complicated behavioral states Orexin antagonists for neuropsychiatric disease: progress and potential pitfalls Multiple roles for orexin/hypocretin in addiction The dual orexin/hypocretin receptor antagonist, almorexant, in the ventral tegmental area attenuates ethanol self-administration Orexin/hypocretin role in reward: implications for opioid and other addictions Binge-like consumption of ethanol and other salient reinforcers is blocked by orexin-1 receptor inhibition and leads to a reduction of hypothalamic orexin immunoreactivity.Orexin-1 receptor antagonism does not reduce the rewarding potency of cocaine in Swiss-Webster mice.Hypothalamic neuropeptide signaling in alcohol addiction The importance of the 6- and 7-positions of tetrahydroisoquinolines as selective antagonists for the orexin 1 receptor.The orexin-1 receptor antagonist SB-334867 decreases sympathetic responses to a moderate dose of methamphetamine and stress Role of orexin-1 receptor mechanisms on compulsive food consumption in a model of binge eating in female rats.Differential orexin/hypocretin expression in addiction-prone and -resistant rats selectively bred for high (HiS) and low (LoS) saccharin intake.Prenatal exposure to ethanol stimulates hypothalamic CCR2 chemokine receptor system: Possible relation to increased density of orexigenic peptide neurons and ethanol drinking in adolescent offspring The role of orexins/hypocretins in alcohol use and abuse: an appetitive-reward relationship.Opioids in the perifornical lateral hypothalamus suppress ethanol drinking.Effects of embryonic ethanol exposure at low doses on neuronal development, voluntary ethanol consumption and related behaviors in larval and adult zebrafish: Role of hypothalamic orexigenic peptides.Systems level neuroplasticity in drug addiction.The hypocretins and the reward function: what have we learned so far?Complementary roles of orexin and melanin-concentrating hormone in feeding behavior.The role of the glucocorticoids in developing resilience to stress and addiction.Orexin Receptor Targets for Anti-Relapse Medication Development in Drug Addiction.The use of the reinstatement model to study relapse to palatable food seeking during dieting.Orexin receptors within the nucleus accumbens shell mediate the stress but not drug priming-induced reinstatement of morphine conditioned place preference Orexin-1 and orexin-2 receptor antagonists reduce ethanol self-administration in high-drinking rodent models Neurobiology of consummatory behavior: mechanisms underlying overeating and drug use.Roux en Y gastric bypass increases ethanol intake in the rat.The paraventricular nucleus of the thalamus is recruited by both natural rewards and drugs of abuse: recent evidence of a pivotal role for orexin/hypocretin signaling in this thalamic nucleus in drug-seeking behavior.The hypocretin/orexin system: implications for drug reward and relapse.Orexin/hypocretin based pharmacotherapies for the treatment of addiction: DORA or SORA?The role of orexin in motivated behaviours.Orexin-A/Hypocretin-1 Mediates Cocaine-Seeking Behavior in the Posterior Paraventricular Nucleus of the Thalamus via Orexin/Hypocretin Receptor-2.How contexts promote and prevent relapse to drug seeking.The Role of Orexin Signaling in the Ventral Tegmental Area and Central Amygdala in Modulating Binge-Like Ethanol Drinking Behavior.Orexin/hypocretin-1 receptor antagonism reduces ethanol self-administration and reinstatement selectively in highly-motivated rats.Relative potency of varenicline or fluvoxamine to reduce responding for ethanol versus food depends on the presence or absence of concurrently earned food Different levels in orexin concentrations and risk factors associated with higher orexin levels: comparison between detoxified opiate and methamphetamine addicts in 5 Chinese cities.Central orexin (hypocretin) 2 receptor antagonism reduces ethanol self-administration, but not cue-conditioned ethanol-seeking, in ethanol-preferring rats.The dual orexin receptor antagonist almorexant, alone and in combination with morphine, cocaine and amphetamine, on conditioned place preference and locomotor sensitization in the rat.Differential role of hypothalamic orexin/hypocretin neurons in reward seeking motivated by cocaine versus palatable food.

P2860

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P2860

Selective blockade of the orexin-2 receptor attenuates ethanol self-administration, place preference, and reinstatement.

http://www.wikidata.org/entity/Q51892779

description

2010 nî lūn-bûn

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2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年學術文章

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2010年學術文章

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name

Selective blockade of the orex ...... preference, and reinstatement.

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Selective blockade of the orex ...... preference, and reinstatement.

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type

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Selective blockade of the orex ...... preference, and reinstatement.

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Selective blockade of the orex ...... preference, and reinstatement.

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Selective blockade of the orex ...... preference, and reinstatement.

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Selective blockade of the orex ...... preference, and reinstatement.

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Ian Fraser

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James Palmer

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James R Shoblock

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Jamin Boggs

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Kirsten Morton

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Leah Aluisio

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Natalie Welty

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Nicholas I Carruthers

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Pascal Bonaventure

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Ruggero Galici

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P2860

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity

Orexin receptors: pharmacology and therapeutic opportunities

Orexin mediates the expression of precipitated morphine withdrawal and concurrent activation of the nucleus accumbens shell

Role of lateral hypothalamic orexin neurons in reward processing and addiction

The orexin system regulates alcohol-seeking in rats

The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene

Insomnia, self-medication, and relapse to alcoholism

Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation

Orexin A/hypocretin-1 selectively promotes motivation for positive reinforcers

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