The loss of telomerase activity in highly differentiated CD8+CD28-CD27- T cells is associated with decreased Akt (Ser473) phosphorylation.
about
Immune activation and inflammation in HIV-1 infection: causes and consequencesDynamics of telomerase activity in response to acute psychological stressOxidative stress and age-related changes in T cells: is thalassemia a model of accelerated immune system aging?CD8 T cell persistence in treated HIV infectionMechanistic insights on immunosenescence and chronic immune activation in HIV-tuberculosis co-infectionAging and immune function: molecular mechanisms to interventionsInfluenza-specific T cells from older people are enriched in the late effector subset and their presence inversely correlates with vaccine response.CD28(-) T cells: their role in the age-associated decline of immune function.Is thymocyte development functional in the aged?Immune and myodegenerative pathomechanisms in inclusion body myositisTelomeres and immunological diseases of agingFocus on TILs: prognostic significance of tumor infiltrating lymphocytes in human melanomap38 signaling inhibits mTORC1-independent autophagy in senescent human CD8⁺ T cells.Telomerase and primary T cells: biology and immortalization for adoptive immunotherapy.The kinase p38 activated by the metabolic regulator AMPK and scaffold TAB1 drives the senescence of human T cells.Immunopathogenesis of asymptomatic chronic HIV Infection: the calm before the storm.Identification and characterization of a cytotoxic T-lymphocyte agonist epitope of brachyury, a transcription factor involved in epithelial to mesenchymal transition and metastasis.Interleukin-7 inhibits tumor-induced CD27-CD28- suppressor T cells: implications for cancer immunotherapy.The aging immune system and its relationship with cancerRole of CD8 T Cell Replicative Senescence in Human Aging and in HIV-mediated ImmunosenescenceHIV-1 induces telomerase activity in monocyte-derived macrophages, possibly safeguarding one of its reservoirs.HCV monoinfection and HIV/HCV coinfection enhance T-cell immune senescence in injecting drug users early during infectionFunctional skewing of the global CD8 T cell population in chronic hepatitis B virus infection.Immunity, ageing and cancer.Telomerase activity of HIV-1-specific CD8+ T cells: constitutive up-regulation in controllers and selective increase by blockade of PD ligand 1 in progressorsPolyfunctional Melan-A-specific tumor-reactive CD8(+) T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS.Dynamics of T cell memory in human cytomegalovirus infection.Telomerase insufficiency in rheumatoid arthritis.Adenosine deaminase modulation of telomerase activity and replicative senescence in human CD8 T lymphocytes.KLRG1--more than a marker for T cell senescence.T-cell redeployment and intracellular cytokine expression following exercise: effects of exercise intensity and cytomegalovirus infection.A sestrin-dependent Erk-Jnk-p38 MAPK activation complex inhibits immunity during agingIncreased numbers of preexisting memory CD8 T cells and decreased T-bet expression can restrain terminal differentiation of secondary effector and memory CD8 T cells.Generating diversity: transcriptional regulation of effector and memory CD8 T-cell differentiation.Telomere/telomerase interplay in virus-driven and virus-independent lymphomagenesis: pathogenic and clinical implications.Generation of effector CD8+ T cells and their conversion to memory T cells.Human telomerase activity regulation.Gain and loss of T cell subsets in old age--age-related reshaping of the T cell repertoire.CD8+ CD28- and CD8+ CD57+ T cells and their role in health and disease.The Many Unknowns Concerning the Bioenergetics of Exhaustion and Senescence during Chronic Viral Infection.
P2860
Q22252860-106BF69F-436B-4E85-974C-87D007D80E7EQ24634297-7BE6DB94-EB3E-4110-B122-934DEC720288Q26752041-B4CEB6A4-4909-43B6-8D3F-9348D4E180EBQ27014768-F52DF953-5A4F-46A1-B025-D2C3E9759DDEQ28081838-5271C4FA-7105-461A-949F-75761E1D6DE5Q28387056-49654840-1E1D-4DA1-B6A2-0897ED4C1CADQ31030019-CFE1009C-B198-4AA9-AB40-1D421C957832Q33572405-99A8B09F-9741-478B-9E60-B0A2F458DAD9Q33588677-BB31209B-E71A-4864-B02A-8FF289EAC9C6Q33753870-B0BD2709-3563-46E9-A948-3CB60177E07AQ34051060-8616238F-2E28-4606-85CC-74C3B5EC3F62Q34111789-46BEA7EA-6B22-48A5-B51A-B42F377ACFF9Q34117494-C56CC7EF-6F0F-427F-942A-9D1DE3D8B1CFQ34170012-F789D25E-011F-42A2-A6B6-AD75CFE4441EQ34310345-F768774F-82FA-4133-9B82-025D07D7CE7FQ34608946-4EC36C45-19BC-4BF2-A95D-546166808E62Q34642305-AA3894FA-9985-442A-8815-2D4A7857B0C5Q35146532-D34D4E37-DF11-44AD-92C5-604D0CAB1E8DQ35569843-7379D346-ECD3-4A4F-8FA7-D5044BA8CCA7Q35720116-16D70CF5-39B8-4AB2-9804-C5E35162DC87Q36276462-3D571A0A-4E4E-4D64-A419-7535F32E14DBQ36748931-85A98974-8070-4BF9-80BE-15FFBD839393Q36853435-436C0F65-F75B-4F40-AB70-089835129522Q36930979-48D04053-08CB-4456-984B-DDA4E1C9451DQ36948586-7BAB2C52-3416-42FE-B0BB-FFF8EA7AB59BQ37012650-49D176C9-1350-4E6A-8A17-77F0C8247B6AQ37095344-CE14AD12-EEB5-4071-9AE1-9CE484A28810Q37132884-BEDC3968-41D6-417F-A1AE-908B1351BE9AQ37169526-445201D4-1ADD-4E8D-9C13-65F972A3B661Q37500069-1AA961E1-512E-459C-93BC-23CA45358B7BQ37599595-35D48378-1B9E-45E9-8E11-3064F1F43D2EQ37660345-B58DF431-41F7-438A-A0B8-FBBD8327D235Q37709956-61D08B0C-4FB2-4DE6-9A8C-F54E10B3BC49Q37764002-BCD0FCC0-4064-4EEB-81CB-59DDF9E3F638Q37765230-F1DA6882-E331-462F-8325-BC86299AEDD8Q37773428-B7B239F7-71C9-4E8F-B47C-A70C947C9F15Q37810521-31E5F955-9F3E-4DA3-9076-50202451BB0DQ37829691-6535FA61-CD1E-4AB7-807B-EB10BB2F60B2Q37895329-8067C1D4-3B31-4F1E-AC76-39B5548783E1Q38259565-E4A38F26-C2BD-492F-B42F-B9E764C843BD
P2860
The loss of telomerase activity in highly differentiated CD8+CD28-CD27- T cells is associated with decreased Akt (Ser473) phosphorylation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
The loss of telomerase activit ...... Akt (Ser473) phosphorylation.
@en
The loss of telomerase activit ...... associated with decreased Akt
@nl
type
label
The loss of telomerase activit ...... Akt (Ser473) phosphorylation.
@en
The loss of telomerase activit ...... associated with decreased Akt
@nl
prefLabel
The loss of telomerase activit ...... Akt (Ser473) phosphorylation.
@en
The loss of telomerase activit ...... associated with decreased Akt
@nl
P2093
P1476
The loss of telomerase activit ...... Akt (Ser473) phosphorylation.
@en
P2093
Alastair D G Lawson
Arne N Akbar
David Webster
Fiona J Plunkett
Helene M Finney
Inderjeet Dokal
Lavina L Belaramani
Mike Salmon
Ornella Franzese
P304
P356
10.4049/JIMMUNOL.178.12.7710
P407
P577
2007-06-01T00:00:00Z