Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells.
about
Histone deacetylase-independent transcriptional repression by methyl-CpG-binding protein 2.MCAF mediates MBD1-dependent transcriptional repressionIsolation of an FMRP-associated messenger ribonucleoprotein particle and identification of nucleolin and the fragile X-related proteins as components of the complexFragile X syndrome: loss of local mRNA regulation alters synaptic development and functionTherapeutic potential of mood stabilizers lithium and valproic acid: beyond bipolar disorderFragile X (CGG)n repeats induce a transcriptional repression in cis upon a linked promoter: evidence for a chromatin mediated effectThe gene encoding the fragile X RNA-binding protein is controlled by nuclear respiratory factor 2 and the CREB family of transcription factors.Transcriptional Reactivation of the FMR1 Gene. A Possible Approach to the Treatment of the Fragile X SyndromeEpigenetics and Triplet-Repeat Neurological DiseasesSingle-Nucleotide Mutations in FMR1 Reveal Novel Functions and Regulatory Mechanisms of the Fragile X Syndrome Protein FMRPRepeat-mediated genetic and epigenetic changes at the FMR1 locus in the Fragile X-related disordersThe unstable repeats--three evolving faces of neurological diseaseModeling Fragile X Syndrome Using Human Pluripotent Stem CellsThe promise and perils of HDAC inhibitors in neurodegenerationInteraction of the transcription factors USF1, USF2, and alpha -Pal/Nrf-1 with the FMR1 promoter. Implications for Fragile X mental retardation syndromeThe fragile X gene and its functionMethylation-mediated silencing of TMS1/ASC is accompanied by histone hypoacetylation and CpG island-localized changes in chromatin architectureRNA and microRNAs in fragile X mental retardationMethylation-dependent gene silencing induced by interleukin 1beta via nitric oxide productionTranscriptional repression of BRCA1 by aberrant cytosine methylation, histone hypoacetylation and chromatin condensation of the BRCA1 promoterSite-specific methylation of the promoter alters deoxyribonucleic acid-protein interactions and prevents follicle-stimulating hormone receptor gene transcription.CGG allele size somatic mosaicism and methylation in FMR1 premutation alleles.MeCP2 driven transcriptional repression in vitro: selectivity for methylated DNA, action at a distance and contacts with the basal transcription machinery.Histone deacetylases suppress CGG repeat-induced neurodegeneration via transcriptional silencing in models of fragile X tremor ataxia syndrome.Cross talk between microRNA and epigenetic regulation in adult neurogenesis.CpG and Non-CpG Methylation in Epigenetic Gene Regulation and Brain FunctioniPSC-derived forebrain neurons from FXS individuals show defects in initial neurite outgrowthDemethylation, reactivation, and destabilization of human fragile X full-mutation alleles in mouse embryocarcinoma cells.Methylation-dependent silencing of the reduced folate carrier gene in inherently methotrexate-resistant human breast cancer cells.DNA methylation and histone deacetylation in the control of gene expression: basic biochemistry to human development and disease.Hypomethylation of an expanded FMR1 allele is not associated with a global DNA methylation defect.Rett syndrome and beyond: recurrent spontaneous and familial MECP2 mutations at CpG hotspotsSequence-dependent dynamics of duplex DNA: the applicability of a dinucleotide modelClinical and molecular implications of mosaicism in FMR1 full mutations.The distribution of repressive histone modifications on silenced FMR1 alleles provides clues to the mechanism of gene silencing in fragile X syndrome.Precipitous release of methyl-CpG binding protein 2 and histone deacetylase 1 from the methylated human multidrug resistance gene (MDR1) on activation.Heterogeneity in the modification and involvement of chromatin components of the CpG island of the silenced human CDH1 gene in cancer cells.FMR1 and the fragile X syndrome: human genome epidemiology reviewParent-of-origin specific histone acetylation and reactivation of a key imprinted gene locus in Prader-Willi syndrome.Epigenetic characterization of the FMR1 promoter in induced pluripotent stem cells from human fibroblasts carrying an unmethylated full mutation
P2860
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P2860
Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh-hant
name
Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells.
@en
Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells.
@nl
type
label
Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells.
@en
Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells.
@nl
prefLabel
Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells.
@en
Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells.
@nl
P2093
P356
P1433
P1476
Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells.
@en
P2093
P2888
P304
P356
10.1038/8807
P407
P577
1999-05-01T00:00:00Z