Transfer of the human telomerase reverse transcriptase (TERT) gene into T lymphocytes results in extension of replicative potential.
about
Telomerase-based pharmacologic enhancement of antiviral function of human CD8+ T lymphocytesAdoptive T cell therapy for cancer in the clinicTechnical Considerations for the Generation of Adoptively Transferred T Cells in Cancer ImmunotherapyConditional immortalization of human B cells by CD40 ligation.Age-associated telomere attrition of lymphocytes in vivo is co-ordinated with changes in telomerase activity, composition of lymphocyte subsets and health conditions.Telomeres and immunological diseases of agingDissociation of telomerase activity and telomere length maintenance in primitive human hematopoietic cells.The association of telomere length and genetic variation in telomere biology genes.Telomerase and primary T cells: biology and immortalization for adoptive immunotherapy.Telomere length of transferred lymphocytes correlates with in vivo persistence and tumor regression in melanoma patients receiving cell transfer therapy.Telomerase in the human organism.Senescence: does it all happen at the ends?High-efficiency transfection of primary human and mouse T lymphocytes using RNA electroporationDifferential impairment of lytic and cytokine functions in senescent human immunodeficiency virus type 1-specific cytotoxic T lymphocytes.Telomeres in T and B cells.Acute exercise leads to regulation of telomere-associated genes and microRNA expression in immune cells.Immortalization of human and rhesus macaque primary antigen-specific T cells by retrovirally transduced telomerase reverse transcriptase.Analyses and comparisons of telomerase activity and telomere length in human T and B cells: insights for epidemiology of telomere maintenanceCytokine-independent growth and clonal expansion of a primary human CD8+ T-cell clone following retroviral transduction with the IL-15 gene.Telomere loss, senescence, and genetic instability in CD4+ T lymphocytes overexpressing hTERT.Persistence of tumor infiltrating lymphocytes in adoptive immunotherapy correlates with telomere length.Telomerase activation and rejuvenation of telomere length in stimulated T cells derived from serially transplanted hematopoietic stem cellsReverse immunology approach for the identification of CD8 T-cell-defined antigens: advantages and hurdles.Accelerated telomere erosion is associated with a declining immune function of caregivers of Alzheimer's disease patientsTelomere and adaptive immunityTelomerase is an independent prognostic marker of overall survival in patients with colorectal cancer.Telomerase is involved in IL-7-mediated differential survival of naive and memory CD4+ T cells.Improving therapy of chronic lymphocytic leukemia with chimeric antigen receptor T cellsEnhancement of the in vivo persistence and antitumor efficacy of CD19 chimeric antigen receptor T cells through the delivery of modified TERT mRNA.Latent membrane protein 1 of Epstein-Barr virus activates the hTERT promoter and enhances telomerase activity in B lymphocytes.Expansion of human regulatory T-cells from patients with type 1 diabetes.Adoptive cell therapy for patients with melanoma, using tumor-infiltrating lymphocytes genetically engineered to secrete interleukin-2.Telomerase insufficiency in rheumatoid arthritis.Immortalized B cells: a neverending source of antigen-presenting cells for vaccines?Adoptive T cell transfer for cancer immunotherapy in the era of synthetic biology.Replicative potential of human natural killer cells.Telomere length in cardiovascular disease: new challenges in measuring this marker of cardiovascular aging.Adoptive immunotherapy for cancer.Telomeres, telomerase and colorectal cancer.Going viral: chimeric antigen receptor T-cell therapy for hematological malignancies.
P2860
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P2860
Transfer of the human telomerase reverse transcriptase (TERT) gene into T lymphocytes results in extension of replicative potential.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Transfer of the human telomera ...... sion of replicative potential.
@en
Transfer of the human telomerase reverse transcriptase
@nl
type
label
Transfer of the human telomera ...... sion of replicative potential.
@en
Transfer of the human telomerase reverse transcriptase
@nl
prefLabel
Transfer of the human telomera ...... sion of replicative potential.
@en
Transfer of the human telomerase reverse transcriptase
@nl
P2093
P356
P1433
P1476
Transfer of the human telomera ...... sion of replicative potential.
@en
P2093
Antonchuk J
Lansdorp PM
Migliaccio M
P304
P356
10.1182/BLOOD.V98.3.597
P407
P577
2001-08-01T00:00:00Z