Evolution of functionally conserved enhancers can be accelerated in large populations: a population-genetic model.
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The rate of establishment of complex adaptationsWaiting for two mutations: with applications to regulatory sequence evolution and the limits of Darwinian evolutionWhat does it take to evolve an enhancer? A simulation-based study of factors influencing the emergence of combinatorial regulationContingency and entrenchment in protein evolution under purifying selectionScaling expectations for the time to establishment of complex adaptationsThe origin of subfunctions and modular gene regulation.Cryptic genetic variation can make “irreducible complexity” a common mode of adaptation in sexual populationsThe functional genomic distribution of protein divergence in two animal phyla: coevolution, genomic conflict, and constraint.The evolution of combinatorial gene regulation in fungi.Evolution of the leukotoxin promoter in genus Mannheimia.Naturally occurring deletions of hunchback binding sites in the even-skipped stripe 3+7 enhancerThe rate of fitness-valley crossing in sexual populations.Experiments on the role of deleterious mutations as stepping stones in adaptive evolutionMissense meanderings in sequence space: a biophysical view of protein evolution.Adaptive evolution and the birth of CTCF binding sites in the Drosophila genomeCompensatory cis-trans evolution and the dysregulation of gene expression in interspecific hybrids of DrosophilaThe rank ordering of genotypic fitness values predicts genetic constraint on natural selection on landscapes lacking sign epistasis.Patterns and evolution of ACGT repeat cis-element landscape across four plant genomesPhylogenetic simulation of promoter evolution: estimation and modeling of binding site turnover events and assessment of their impact on alignment tools.Genome clashes in hybrids: insights from gene expression.Complex role of space in the crossing of fitness valleys by asexual populations.The rate at which asexual populations cross fitness valleys.Accelerated crossing of fitness valleys through division of labor and cheating in asexual populations.Aneuploidy underlies rapid adaptive evolution of yeast cells deprived of a conserved cytokinesis motor.Deterministic and stochastic regimes of asexual evolution on rugged fitness landscapes.Fitness valleys constrain HIV-1's adaptation to its secondary chemokine coreceptor.On the findability of genotypes.Escaping an evolutionary lobster trap: drug resistance and compensatory mutation in a fluctuating environment.
P2860
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P2860
Evolution of functionally conserved enhancers can be accelerated in large populations: a population-genetic model.
description
2002 nî lūn-bûn
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2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
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2002年學術文章
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2002年學術文章
@zh-hant
name
Evolution of functionally cons ...... s: a population-genetic model.
@en
Evolution of functionally cons ...... s: a population-genetic model.
@nl
type
label
Evolution of functionally cons ...... s: a population-genetic model.
@en
Evolution of functionally cons ...... s: a population-genetic model.
@nl
prefLabel
Evolution of functionally cons ...... s: a population-genetic model.
@en
Evolution of functionally cons ...... s: a population-genetic model.
@nl
P2860
P356
P1476
Evolution of functionally cons ...... s: a population-genetic model.
@en
P2093
Ashley J R Carter
Günter P Wagner
P2860
P304
P356
10.1098/RSPB.2002.1968
P577
2002-05-01T00:00:00Z