Plasma growth hormone pulse activation of hepatic JAK-STAT5 signaling: developmental regulation and role in male-specific liver gene expression.
about
Exploring hepatic hormone actions using a compilation of gene expression profiles.Characterization of three growth hormone-responsive transcription factors preferentially expressed in adult female liverSignalling cross-talk between hepatocyte nuclear factor 4alpha and growth-hormone-activated STAT5bInhibitory cross-talk between STAT5b and liver nuclear factor HNF3beta: impact on the regulation of growth hormone pulse-stimulated, male-specific liver cytochrome P-450 gene expressionChild health, developmental plasticity, and epigenetic programmingIn vivo analysis of growth hormone receptor signaling domains and their associated transcripts.In vivo targeting of the growth hormone receptor (GHR) Box1 sequence demonstrates that the GHR does not signal exclusively through JAK2.Intrinsic sex differences in the early growth hormone responsiveness of sex-specific genes in mouse liverEvidence that sensitivity to growth hormone (GH) is growth period and tissue type dependent: studies in GH-deficient lit/lit mice.Epigenetic mechanisms involved in developmental nutritional programming.Dynamic, sex-differential STAT5 and BCL6 binding to sex-biased, growth hormone-regulated genes in adult mouse liverLoss of sexually dimorphic liver gene expression upon hepatocyte-specific deletion of Stat5a-Stat5b locusDisruption of STAT5b-Regulated Sexual Dimorphism of the Liver Transcriptome by Diverse Factors Is a Common EventSex-specific mouse liver gene expression: genome-wide analysis of developmental changes from pre-pubertal period to young adulthood.Impact of CUX2 on the female mouse liver transcriptome: activation of female-biased genes and repression of male-biased genes.Sexually Dimorphic Expression of eGFP Transgene in the Akr1A1 Locus of Mouse Liver Regulated by Sex Hormone-Related Epigenetic Remodeling.Role of STAT5a in regulation of sex-specific gene expression in female but not male mouse liver revealed by microarray analysis.Genome-wide analysis of chromatin states reveals distinct mechanisms of sex-dependent gene regulation in male and female mouse liverSex differences in the expression of hepatic drug metabolizing enzymes.Dynamic in vivo binding of STAT5 to growth hormone-regulated genes in intact rat liver. Sex-specific binding at low- but not high-affinity STAT5 sites.Sex-specific early growth hormone response genes in rat liver.Male-specific hepatic Bcl6: growth hormone-induced block of transcription elongation in females and binding to target genes inversely coordinated with STAT5Synergistic action of hepatocyte nuclear factors 3 and 6 on CYP2C12 gene expression and suppression by growth hormone-activated STAT5b. Proposed model for female specific expression of CYP2C12 in adult rat liver.Skeletal effects of growth hormone and insulin-like growth factor-I therapy.Role of the cytokine-induced SH2 domain-containing protein CIS in growth hormone receptor internalization.Role of hepatocyte nuclear factors in transcriptional regulation of male-specific CYP2A2.Feminization of male mouse liver by persistent growth hormone stimulation: Activation of sex-biased transcriptional networks and dynamic changes in chromatin states.Sexual dimorphism of rat liver nuclear proteins: regulatory role of growth hormone.Functional roles of sex-biased, growth hormone-regulated microRNAs miR-1948 and miR-802 in young adult mouse liver.The decrease in mature myostatin protein in male skeletal muscle is developmentally regulated by growth hormone.Role of the Cytokine-inducible SH2 Protein CIS in Desensitization of STAT5b Signaling by Continuous Growth Hormone
P2860
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P2860
Plasma growth hormone pulse activation of hepatic JAK-STAT5 signaling: developmental regulation and role in male-specific liver gene expression.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
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2000年學術文章
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2000年學術文章
@zh-hant
name
Plasma growth hormone pulse ac ...... pecific liver gene expression.
@en
Plasma growth hormone pulse ac ...... pecific liver gene expression.
@nl
type
label
Plasma growth hormone pulse ac ...... pecific liver gene expression.
@en
Plasma growth hormone pulse ac ...... pecific liver gene expression.
@nl
prefLabel
Plasma growth hormone pulse ac ...... pecific liver gene expression.
@en
Plasma growth hormone pulse ac ...... pecific liver gene expression.
@nl
P356
P1433
P1476
Plasma growth hormone pulse ac ...... pecific liver gene expression.
@en
P2093
P304
P356
10.1210/EN.141.9.3245
P407
P577
2000-09-01T00:00:00Z