The bHLH transcription factor dHAND controls Sonic hedgehog expression and establishment of the zone of polarizing activity during limb development.
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Developmental basis for hind-limb loss in dolphins and origin of the cetacean bodyplanRole of Dlx6 in regulation of an endothelin-1-dependent, dHAND branchial arch enhancer.Altered Twist1 and Hand2 dimerization is associated with Saethre-Chotzen syndrome and limb abnormalitiesThe basic helix-loop-helix transcription factors dHAND and eHAND exhibit dimerization characteristics that suggest complex regulation of functionMutual genetic antagonism involving GLI3 and dHAND prepatterns the vertebrate limb bud mesenchyme prior to SHH signalingA novel acropectoral syndrome maps to chromosome 7q36Distinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud developmentGATA6 is a crucial regulator of Shh in the limb budGata6-Dependent GLI3 Repressor Function is Essential in Anterior Limb Progenitor Cells for Proper Limb DevelopmentHand2 is required in the epithelium for palatogenesis in miceCauli: a mouse strain with an Ift140 mutation that results in a skeletal ciliopathy modelling Jeune syndromeEndothelin-A receptor-dependent and -independent signaling pathways in establishing mandibular identityEvidence for an amphibian sixth digitMolecular development of chondrichthyan claspers and the evolution of copulatory organsHeterochronic shift in Hox-mediated activation of sonic hedgehog leads to morphological changes during fin developmentGeneChip analysis of human embryonic stem cell differentiation into hemangioblasts: an in silico dissection of mixed phenotypes.Understanding the basis of auriculocondylar syndrome: Insights from human, mouse and zebrafish genetic studies.dHAND-Cre transgenic mice reveal specific potential functions of dHAND during craniofacial developmentTimed deletion of Twist1 in the limb bud reveals age-specific impacts on autopod and zeugopod patterningPdlim7 is required for maintenance of the mesenchymal/epidermal Fgf signaling feedback loop during zebrafish pectoral fin development.Transcripts encoding HAND genes are differentially expressed and regulated by BMP4 and GDNF in developing avian gut.Nipbl and mediator cooperatively regulate gene expression to control limb development.Axial Hox9 activity establishes the posterior field in the developing forelimb.HMGB factors are required for posterior digit development through integrating signaling pathway activitiesPatterning the limb before and after SHH signalling.HAND2 targets define a network of transcriptional regulators that compartmentalize the early limb bud mesenchyme.Gfi/Pag-3/senseless zinc finger proteins: a unifying theme?The Transcription Factor Hand1 Is Involved In Runx2-Ihh-Regulated Endochondral Ossification.Anteroposterior Limb Skeletal Patterning Requires the Bifunctional Action of SWI/SNF Chromatin Remodeling Complex in Hedgehog PathwayUse of a Conditional Ubr5 Mutant Allele to Investigate the Role of an N-End Rule Ubiquitin-Protein Ligase in Hedgehog Signalling and Embryonic Limb Development.Transcriptomics analysis of early embryonic stem cell differentiation under osteoblast culture conditions: Applications for detection of developmental toxicity.A genome-scale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limbAn endothelin-1 switch specifies maxillomandibular identity.Transcriptional components of anteroposterior positional information during zebrafish fin regeneration.DNA binding-dependent and -independent functions of the Hand2 transcription factor during mouse embryogenesis.A twist of insight - the role of Twist-family bHLH factors in development.Transcription of the non-coding RNA upperhand controls Hand2 expression and heart development.A Gli silencer is required for robust repression of gremlin in the vertebrate limb bud.Pbx homeodomain proteins: TALEnted regulators of limb patterning and outgrowth.Twist factor regulation of non-cardiomyocyte cell lineages in the developing heart.
P2860
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P2860
The bHLH transcription factor dHAND controls Sonic hedgehog expression and establishment of the zone of polarizing activity during limb development.
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The bHLH transcription factor ...... ivity during limb development.
@en
The bHLH transcription factor ...... ivity during limb development.
@nl
type
label
The bHLH transcription factor ...... ivity during limb development.
@en
The bHLH transcription factor ...... ivity during limb development.
@nl
prefLabel
The bHLH transcription factor ...... ivity during limb development.
@en
The bHLH transcription factor ...... ivity during limb development.
@nl
P2093
P1433
P1476
The bHLH transcription factor ...... ivity during limb development.
@en
P2093
P304
P407
P577
2000-06-01T00:00:00Z