Nerve growth factor induces survival and differentiation through two distinct signaling cascades in PC12 cells.
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Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy.R-Ras3/M-Ras induces neuronal differentiation of PC12 cells through cell-type-specific activation of the mitogen-activated protein kinase cascade.Negative regulation of PI 3-kinase by Ruk, a novel adaptor proteinActivation of anaplastic lymphoma kinase receptor tyrosine kinase induces neuronal differentiation through the mitogen-activated protein kinase pathwayProtein-tyrosine phosphatase (PTP) wedge domain peptides: a novel approach for inhibition of PTP function and augmentation of protein-tyrosine kinase functionREN: a novel, developmentally regulated gene that promotes neural cell differentiationThe protein phosphatase 2A regulatory subunits B'beta and B'delta mediate sustained TrkA neurotrophin receptor autophosphorylation and neuronal differentiationCorticotropin-releasing hormone induces Fas ligand production and apoptosis in PC12 cells via activation of p38 mitogen-activated protein kinaseRit mutants confirm role of MEK/ERK signaling in neuronal differentiation and reveal novel Par6 interaction.The regulation of presenilin-1 by nerve growth factor.Opposite effects of the Hsp90 inhibitor Geldanamycin: induction of apoptosis in PC12, and differentiation in N2A cells.Nerve growth factor prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced cell death via the Akt pathway by suppressing caspase-3-like activity using PC12 cells: relevance to therapeutical application for Parkinson's disease.c-Jun N-terminal kinase in synergistic neurite outgrowth in PC12 cells mediated through P90RSK.Extracellular signal-regulated kinase 1/2 plays a pro-life role in experimental brain stem death via MAPK signal-interacting kinase at rostral ventrolateral medulla.The zinc finger transcription factor Klf7 is required for TrkA gene expression and development of nociceptive sensory neurons.Mapping of atypical protein kinase C within the nerve growth factor signaling cascade: relationship to differentiation and survival of PC12 cells.Shoc2/Sur8 protein regulates neurite outgrowthPotentiation of neuritogenic activity of medicinal mushrooms in rat pheochromocytoma cellsThe Ras/Raf/MEK/extracellular signal-regulated kinase pathway induces autocrine-paracrine growth inhibition via the leukemia inhibitory factor/JAK/STAT pathway.A rit GTPase-p38 mitogen-activated protein kinase survival pathway confers resistance to cellular stress.Role for Egr1 in the Transcriptional Program Associated with Neuronal Differentiation of PC12 Cells.Nerve Growth Factor Regulates Transient Receptor Potential Vanilloid 2 via Extracellular Signal-Regulated Kinase Signaling To Enhance Neurite Outgrowth in Developing NeuronsDistinctive effect on nerve growth factor-induced PC12 cell neurite outgrowth by two unique neolignan enantiomers from Illicium merrillianum.GGA3 mediates TrkA endocytic recycling to promote sustained Akt phosphorylation and cell survival.Acute mitochondrial inhibition by mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK) 1/2 inhibitors regulates proliferation.The herpes simplex virus type 2 gene ICP10PK protects from apoptosis caused by nerve growth factor deprivation through inhibition of caspase-3 activation and XIAP up-regulation.Requirement for nitric oxide activation of p21(ras)/extracellular regulated kinase in neuronal ischemic preconditioningProgesterone increases brain-derived neuroptrophic factor expression and protects against glutamate toxicity in a mitogen-activated protein kinase- and phosphoinositide-3 kinase-dependent manner in cerebral cortical explants.Spatial and Temporal Analysis of Active ERK in the C. elegans Germline.Separate cyclic AMP sensors for neuritogenesis, growth arrest, and survival of neuroendocrine cells.SHP-2 deletion in postmigratory neural crest cells results in impaired cardiac sympathetic innervation.Perineural invasion and associated pain in pancreatic cancer.IFI16 is an essential mediator of growth inhibition, but not differentiation, induced by the leukemia inhibitory factor/JAK/STAT pathway in medullary thyroid carcinoma cells.Analysis of the ERK1,2 transcriptome in mammary epithelial cellsSur8/Shoc2 involves both inhibition of differentiation and maintenance of self-renewal of neural progenitor cells via modulation of extracellular signal-regulated kinase signaling.Neuronal exosomes facilitate synaptic pruning by up-regulating complement factors in microglia.Nitric oxide synthase mediates PC12 differentiation induced by the surface topography of nanostructured TiO2.A trifluoromethyl analog of verbenachalcone promotes neurite outgrowth and cell proliferation of NeuroScreen-1 cells.Neuroprotection signaling pathway of nerve growth factor and brain-derived neurotrophic factor against staurosporine induced apoptosis in hippocampal H19-7/IGF-IR [corrected].Boolean Modeling Reveals the Necessity of Transcriptional Regulation for Bistability in PC12 Cell Differentiation.
P2860
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P2860
Nerve growth factor induces survival and differentiation through two distinct signaling cascades in PC12 cells.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh-hant
name
Nerve growth factor induces su ...... naling cascades in PC12 cells.
@en
Nerve growth factor induces su ...... naling cascades in PC12 cells.
@nl
type
label
Nerve growth factor induces su ...... naling cascades in PC12 cells.
@en
Nerve growth factor induces su ...... naling cascades in PC12 cells.
@nl
prefLabel
Nerve growth factor induces su ...... naling cascades in PC12 cells.
@en
Nerve growth factor induces su ...... naling cascades in PC12 cells.
@nl
P2093
P356
P1433
P1476
Nerve growth factor induces su ...... naling cascades in PC12 cells.
@en
P2093
P2888
P304
P356
10.1038/SJ.ONC.1202524
P407
P577
1999-03-01T00:00:00Z