Bruton's tyrosine kinase as an inhibitor of the Fas/CD95 death-inducing signaling complex.
about
Direct inhibition of Bruton's tyrosine kinase by IBtk, a Btk-binding proteinThe kinase Btk negatively regulates the production of reactive oxygen species and stimulation-induced apoptosis in human neutrophilsA new c-Jun N-terminal kinase (JNK)-interacting protein, Sab (SH3BP5), associates with mitochondriaEtk/Bmx as a tumor necrosis factor receptor type 2-specific kinase: role in endothelial cell migration and angiogenesisCrystal structure of Bruton's tyrosine kinase domain suggests a novel pathway for activation and provides insights into the molecular basis of X-linked agammaglobulinemiaThe Bmx tyrosine kinase is activated by IL-3 and G-CSF in a PI-3K dependent mannerThe anti-leukemic Bruton's tyrosine kinase inhibitor alpha-cyano-beta-hydroxy-beta-methyl-N-(2,5-dibromophenyl) propenamide (LFM-A13) prevents fatal thromboembolismProteolytic activation of ETK/Bmx tyrosine kinase by caspasesCoordinating Etk/Bmx activation and VEGF upregulation to promote cell survival and proliferationEndothelial cell-derived CD95 ligand serves as a chemokine in induction of neutrophil slow rolling and adhesionExpression of kinase-defective mutants of c-Src in human metastatic colon cancer cells decreases Bcl-xL and increases oxaliplatin- and Fas-induced apoptosis.Transcription factor STAT5A is a substrate of Bruton's tyrosine kinase in B cells.Chemosensitivity of TEL-AML1 fusion transcript positive acute lymphoblastic leukemia cells.Protein kinases: emerging therapeutic targets in chronic lymphocytic leukemia.Inducible resistance to Fas-mediated apoptosis in B cells.The Tec family of cytoplasmic tyrosine kinases: mammalian Btk, Bmx, Itk, Tec, Txk and homologs in other species.The effects of the Epstein-Barr virus latent membrane protein 2A on B cell function.Receptor-guided 3D-QSAR studies, molecular dynamics simulation and free energy calculations of Btk kinase inhibitorsOptimized Near-IR Fluorescent Agents for in Vivo Imaging of Btk Expression.Novel Bruton's tyrosine kinase inhibitors currently in development.Interactions of the Hdm2/p53 and proteasome pathways may enhance the antitumor activity of bortezomib.Clinical potential of targeting Bruton's tyrosine kinase.A novel isoform of the B cell tyrosine kinase BTK protects breast cancer cells from apoptosis.Coexpression network based on natural variation in human gene expression reveals gene interactions and functions.Bruton's tyrosine kinase as a molecular target in treatment of leukemias and lymphomas as well as inflammatory disorders and autoimmunity.Tec family kinases: regulation of FcεRI-mediated mast-cell activation.Ibrutinib and novel BTK inhibitors in clinical development.Rational design of an immunoconjugate for selective knock-down of leukemia-specific E2A-PBX1 fusion gene expression in human Pre-B leukemia.Bruton's tyrosine kinase: potential target in human multiple myeloma.Hyperthermia enhances tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in human cancer cells.Bruton's tyrosine kinase prevents activation of the anti-apoptotic transcription factor STAT3 and promotes apoptosis in neoplastic B-cells and B-cell precursors exposed to oxidative stress.Amiloride augments TRAIL-induced apoptotic death by inhibiting phosphorylation of kinases and phosphatases associated with the P13K-Akt pathway.Btk is required for an efficient response to erythropoietin and for SCF-controlled protection against TRAIL in erythroid progenitors.Apoptosis induced by the antigen receptor and Fas in a variant of the immature B cell line WEHI-231 and in splenic immature B cells.Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells.Role of a JAK3-dependent biochemical signaling pathway in platelet activation and aggregation.Role of the leukemia-associated transcription factor STAT3 in platelet physiology.SYK and LYN mediate B-cell receptor-independent calcium-induced apoptosis in DT-40 lymphoma B-cells.Hypermethylation of the spleen tyrosine kinase promoter in T-lineage acute lymphoblastic leukemia.Defective expression of Bruton's tyrosine kinase in acute lymphoblastic leukemia.
P2860
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P2860
Bruton's tyrosine kinase as an inhibitor of the Fas/CD95 death-inducing signaling complex.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh-hant
name
Bruton's tyrosine kinase as an ...... th-inducing signaling complex.
@en
Bruton's tyrosine kinase as an ...... th-inducing signaling complex.
@nl
type
label
Bruton's tyrosine kinase as an ...... th-inducing signaling complex.
@en
Bruton's tyrosine kinase as an ...... th-inducing signaling complex.
@nl
prefLabel
Bruton's tyrosine kinase as an ...... th-inducing signaling complex.
@en
Bruton's tyrosine kinase as an ...... th-inducing signaling complex.
@nl
P2093
P2860
P356
P1476
Bruton's tyrosine kinase as an ...... th-inducing signaling complex.
@en
P2093
P2860
P304
P356
10.1074/JBC.274.3.1646
P407
P577
1999-01-01T00:00:00Z