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Modification of epidermal growth factor-like repeats with O-fucose. Molecular cloning and expression of a novel GDP-fucose protein O-fucosyltransferaseEDD, the human hyperplastic discs protein, has a role in progesterone receptor coactivation and potential involvement in DNA damage responseBinding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2Notch Signaling in Neuroendocrine TumorsA Role for Notch Signalling in Breast Cancer and Endocrine ResistanceRobustness and stability of the gene regulatory network involved in DV boundary formation in the Drosophila wingAn expanded Notch-Delta model exhibiting long-range patterning and incorporating MicroRNA regulationA conserved face of the Jagged/Serrate DSL domain is involved in Notch trans-activation and cis-inhibitionDelta-Notch signalling in segmentationMolecular cloning of a xylosyltransferase that transfers the second xylose to O-glucosylated epidermal growth factor repeats of notchFringe is a glycosyltransferase that modifies NotchMouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methodsManic fringe and lunatic fringe modify different sites of the Notch2 extracellular region, resulting in different signaling modulationNotch ligands are substrates for protein O-fucosyltransferase-1 and FringeNotch ligand endocytosis: mechanistic basis of signaling activityNotch signalling in the paraxial mesoderm is most sensitive to reduced Pofut1 levels during early mouse developmentThe Mesp2 transcription factor establishes segmental borders by suppressing Notch activityContext-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In VivoSegmentation defects of Notch pathway mutants and absence of a synergistic phenotype in lunatic fringe/radical fringe double mutant miceO-fucosylation of the notch ligand mDLL1 by POFUT1 is dispensable for ligand functionO-fucosylation of DLL3 is required for its function during somitogenesisProtein O-Glucosyltransferase 1 (POGLUT1) Promotes Mouse Gastrulation through Modification of the Apical Polarity Protein CRUMBS2Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformationEssential roles for lines in mediating leg and antennal proximodistal patterning and generating a stable Notch signaling interface at segment bordersManic fringe inhibits tumor growth by suppressing Notch3 degradation in lung cancerGlycobiology on the fly: developmental and mechanistic insights from DrosophilaMolecular cloning of the Notophthalmus viridescens radical fringe cDNA and characterization of its expression during forelimb development and adult forelimb regeneration.Contributions of chaperone and glycosyltransferase activities of O-fucosyltransferase 1 to Notch signaling.The atypical mammalian ligand Delta-like homologue 1 (Dlk1) can regulate Notch signalling in DrosophilaThe clathrin-binding motif and the J-domain of Drosophila Auxilin are essential for facilitating Notch ligand endocytosis.Neural and synaptic defects in slytherin, a zebrafish model for human congenital disorders of glycosylation.Arbiter of differentiation and death: Notch signaling meets apoptosis.Genome-wide expression profiling in the Drosophila eye reveals unexpected repression of notch signaling by the JAK/STAT pathway.Two Notch ligands, Dll1 and Jag1, are differently restricted in their range of action to control neurogenesis in the mammalian spinal cord.A clock-work somite.Regulation of EGFR and Notch signaling by distinct isoforms of D-cbl during Drosophila developmentFringe modulation of Jagged1-induced Notch signaling requires the action of beta 4galactosyltransferase-1A murine homologue of the Drosophila brainiac gene shows homology to glycosyltransferases and is required for preimplantation development of the mouse.Role of glycosylation of Notch in developmentReciprocal roles for bowl and lines in specifying the peripodial epithelium and the disc proper of the Drosophila wing primordium
P2860
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P2860
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh-hant
name
Fringe modulates Notch-ligand interactions.
@en
Fringe modulates Notch-ligand interactions.
@nl
type
label
Fringe modulates Notch-ligand interactions.
@en
Fringe modulates Notch-ligand interactions.
@nl
prefLabel
Fringe modulates Notch-ligand interactions.
@en
Fringe modulates Notch-ligand interactions.
@nl
P2093
P2860
P356
P1433
P1476
Fringe modulates Notch-ligand interactions.
@en
P2093
K D Irvine
V Papayannopoulos
P2860
P2888
P304
P356
10.1038/43191
P407
P577
1997-06-01T00:00:00Z
P5875
P6179
1035004435