Mechanistic model of G-protein signal transduction. Determinants of efficacy and effect of precoupled receptors.
about
Galpha subunit Gpa2 recruits kelch repeat subunits that inhibit receptor-G protein coupling during cAMP-induced dimorphic transitions in Saccharomyces cerevisiaeCXCR7 controls competition for recruitment of β-arrestin 2 in cells expressing both CXCR4 and CXCR7.Cell transit analysis of ligand-induced stiffening of polymorphonuclear leukocytesA signal transduction pathway model prototype I: From agonist to cellular endpoint.Reduced-order modelling of biochemical networks: application to the GTPase-cycle signalling moduleComputational modeling reveals how interplay between components of a GTPase-cycle module regulates signal transductionA physiological role for the supramolecular organization of rhodopsin and transducin in rod photoreceptors.Gating properties of GIRK channels activated by Galpha(o)- and Galpha(i)-coupled muscarinic m2 receptors in Xenopus oocytes: the role of receptor precoupling in RGS modulation.The C terminus of the Saccharomyces cerevisiae alpha-factor receptor contributes to the formation of preactivation complexes with its cognate G protein.Modeling hypertrophic IP3 transients in the cardiac myocyteUntangling ligand induced activation and desensitization of G-protein-coupled receptors.Expression of a G protein-coupled receptor (GPCR) leads to attenuation of signaling by other GPCRs: experimental evidence for a spontaneous GPCR constitutive inactive form.The dynamics of formation and action of the ternary complex revealed in living cells using a G-protein-gated K+ channel as a biosensor.Calculation of diffusion-limited kinetics for the reactions in collision coupling and receptor cross-linking.Negative cooperativity in binding of muscarinic receptor agonists and GDP as a measure of agonist efficacy.Kinetic diversity in G-protein-coupled receptor signalling.Changes of the responses of single sympathetic ganglionic neurones to substance P following desensitization.
P2860
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P2860
Mechanistic model of G-protein signal transduction. Determinants of efficacy and effect of precoupled receptors.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh-hant
name
Mechanistic model of G-protein ...... ffect of precoupled receptors.
@en
Mechanistic model of G-protein ...... ffect of precoupled receptors.
@nl
type
label
Mechanistic model of G-protein ...... ffect of precoupled receptors.
@en
Mechanistic model of G-protein ...... ffect of precoupled receptors.
@nl
prefLabel
Mechanistic model of G-protein ...... ffect of precoupled receptors.
@en
Mechanistic model of G-protein ...... ffect of precoupled receptors.
@nl
P1476
Mechanistic model of G-protein ...... ffect of precoupled receptors.
@en
P2093
P304
P356
10.1016/S0006-2952(96)00768-X
P407
P577
1997-02-01T00:00:00Z