A structure prediction for the ligand-binding region of the integrin beta subunit: evidence for the presence of a von Willebrand factor A domain.
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Distribution and evolution of von Willebrand/integrin A domains: widely dispersed domains with roles in cell adhesion and elsewhereThe integrins of the urochordate Ciona intestinalis provide novel insights into the molecular evolution of the vertebrate integrin family.The role of alpha and beta chains in ligand recognition by beta 7 integrinsVascular development of the brain requires beta8 integrin expression in the neuroepitheliumThe N-terminal region and the mid-region complex of the integrin beta 2 subunit.Amino acid residues in the PSI domain and cysteine-rich repeats of the integrin beta2 subunit that restrain activation of the integrin alpha(X)beta(2).A minimized human integrin alpha(5)beta(1) that retains ligand recognition.Determination of N- and C-terminal borders of the transmembrane domain of integrin subunits.Identification of multiple integrin beta1 homologs in zebrafish (Danio rerio)Glanzmann thrombasthenia: state of the art and future directions.A 3D structure model of integrin alpha 4 beta 1 complex: I. Construction of a homology model of beta 1 and ligand binding analysisInsights into integrin-ligand binding and activation from the first crystal structure.Lymphocyte function-associated antigen-1 binding residues in intercellular adhesion molecule-2 (ICAM-2) and the integrin binding surface in the ICAM subfamily.Conformational changes in tertiary structure near the ligand binding site of an integrin I domain.beta8 integrins are required for vascular morphogenesis in mouse embryosMUC5AC interactions with integrin β4 enhances the migration of lung cancer cells through FAK signaling.Probing conformational changes in the I-like domain and the cysteine-rich repeat of human beta 3 integrins following disulfide bond disruption by cysteine mutations: identification of cysteine 598 involved in alphaIIbbeta3 activation.Structure-function of the putative I-domain within the integrin beta 2 subunit.A novel leukocyte adhesion deficiency caused by expressed but nonfunctional beta2 integrins Mac-1 and LFA-1.Splice variants of the Drosophila PS2 integrins differentially interact with RGD-containing fragments of the extracellular proteins tiggrin, ten-m, and D-laminin 2.Multiple discontinuous ligand-mimetic antibody binding sites define a ligand binding pocket in integrin alpha(IIb)beta(3).Regulation of integrin function: evidence that bivalent-cation-induced conformational changes lead to the unmasking of ligand-binding sites within integrin alpha5 beta1.The structure of the beta-propeller domain and C-terminal region of the integrin alphaM subunit. Dependence on beta subunit association and prediction of domains.Fine mapping of inhibitory anti-alpha5 monoclonal antibody epitopes that differentially affect integrin-ligand binding.Generation of a minimal alpha5beta1 integrin-Fc fragment.Evidence that ligand and metal ion binding to integrin alpha 4beta 1 are regulated through a coupled equilibrium.Defining the repeating elements in the cysteine-rich region (CRR) of the CD18 integrin beta 2 subunit.Integrin activation involves a conformational change in the alpha 1 helix of the beta subunit A-domain.The interaction of von Willebrand factor-A1 domain with collagen: mutation G1324S (type 2M von Willebrand disease) impairs the conformational change in A1 domain induced by collagen.Analogy and solution scattering modelling: new structural strategies for the multidomain proteins of complement, cartilage and the immunoglobulin superfamily.Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction.Molecular Basis of Ligand Recognition by Integrin α5β1Defining the Topology of Integrin α5β1-Fibronectin Interactions Using Inhibitory Anti-α5 and Anti-β1 Monoclonal AntibodiesMolecular Basis of Ligand Recognition by Integrin α5β1Identification of Amino Acid Residues That Form Part of the Ligand-binding Pocket of Integrin α5β1Long-ranged Protein-glycan Interactions Stabilize von Willebrand Factor A2 Domain from Mechanical Unfolding
P2860
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P2860
A structure prediction for the ligand-binding region of the integrin beta subunit: evidence for the presence of a von Willebrand factor A domain.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh-hant
name
A structure prediction for the ...... on Willebrand factor A domain.
@en
A structure prediction for the ...... on Willebrand factor A domain.
@nl
type
label
A structure prediction for the ...... on Willebrand factor A domain.
@en
A structure prediction for the ...... on Willebrand factor A domain.
@nl
prefLabel
A structure prediction for the ...... on Willebrand factor A domain.
@en
A structure prediction for the ...... on Willebrand factor A domain.
@nl
P1433
P1476
A structure prediction for the ...... on Willebrand factor A domain.
@en
P2093
Tuckwell DS
P304
P356
10.1016/S0014-5793(96)01368-3
P407
P577
1997-01-01T00:00:00Z