Overexpression of the CHRNA5/A3/B4 genomic cluster in mice increases the sensitivity to nicotine and modifies its reinforcing effects.
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Nicotine and the adolescent brainThe habenulo-interpeduncular pathway in nicotine aversion and withdrawalAlternative CHRNB4 3'-UTRs mediate the allelic effects of SNP rs1948 on gene expressionnAChR dysfunction as a common substrate for schizophrenia and comorbid nicotine addiction: Current trends and perspectives.Transgenic over expression of nicotinic receptor alpha 5, alpha 3, and beta 4 subunit genes reduces ethanol intake in mice.Finding genomic function for genetic associations in nicotine addiction research: the ENCODE project's role in future pharmacogenomic analysisThe α3β4* nicotinic ACh receptor subtype mediates physical dependence to morphine: mouse and human studies.Hippocampal changes produced by overexpression of the human CHRNA5/A3/B4 gene cluster may underlie cognitive deficits rescued by nicotine in transgenic mice.Nicotinic acetylcholine receptors control acetylcholine and noradrenaline release in the rodent habenulo-interpeduncular complexChromosome 15q25 (CHRNA3-CHRNB4) Variation Indirectly Impacts Lung Cancer Risk in Chinese MalesSynthesis and nicotinic acetylcholine receptor in vitro and in vivo pharmacological properties of 2'-fluoro-3'-(substituted phenyl)deschloroepibatidine analogues of 2'-fluoro-3'-(4-nitrophenyl)deschloroepibatidine.Functional characterization of AT-1001, an α3β4 nicotinic acetylcholine receptor ligand, at human α3β4 and α4β2 nAChRThe CHRNA3 rs578776 Variant is Associated with an Intrinsic Reward Sensitivity Deficit in Smokers.Use of an α3β4 nicotinic acetylcholine receptor subunit concatamer to characterize ganglionic receptor subtypes with specific subunit composition reveals species-specific pharmacologic properties.Habenular expression of rare missense variants of the β4 nicotinic receptor subunit alters nicotine consumption.Exon sequencing identifies a novel CHRNA3-CHRNA5-CHRNB4 variant that increases the risk for chronic obstructive pulmonary disease.Human Genetics of Addiction: New Insights and Future Directions.Nicotine aversion is mediated by GABAergic interpeduncular nucleus inputs to laterodorsal tegmentum.
P2860
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P2860
Overexpression of the CHRNA5/A3/B4 genomic cluster in mice increases the sensitivity to nicotine and modifies its reinforcing effects.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh-hant
name
Overexpression of the CHRNA5/A ...... ifies its reinforcing effects.
@en
Overexpression of the CHRNA5/A ...... ifies its reinforcing effects.
@nl
type
label
Overexpression of the CHRNA5/A ...... ifies its reinforcing effects.
@en
Overexpression of the CHRNA5/A ...... ifies its reinforcing effects.
@nl
prefLabel
Overexpression of the CHRNA5/A ...... ifies its reinforcing effects.
@en
Overexpression of the CHRNA5/A ...... ifies its reinforcing effects.
@nl
P2093
P2860
P50
P1433
P1476
Overexpression of the CHRNA5/A ...... ifies its reinforcing effects.
@en
P2093
Josefa Sabrià
Lluís Armengol
Martí Pumarola
Michael J Marks
Mònica Gratacòs
Patricia Murtra
Rafael Maldonado
Rubén D Fernández-Montes
Susanna Molas
Xavier Gallego
P2860
P2888
P304
P356
10.1007/S00726-011-1149-Y
P577
2011-11-19T00:00:00Z