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Multi-modality therapeutics with potent anti-tumor effects: photochemical internalization enhances delivery of the fusion toxin scFvMEL/rGelIntracellular re-localisation by photochemical internalisation enhances the cytotoxic effect of gelonin--quantitative studies in normal rat liver.177Lu-DOTA-HH1, a novel anti-CD37 radio-immunoconjugate: a study of toxicity in nude mice.Photochemical internalization of tumor-targeted protein toxins.Photochemical internalisation: a novel drug delivery system.Strongly amphiphilic photosensitizers are not substrates of the cancer stem cell marker ABCG2 and provides specific and efficient light-triggered drug delivery of an EGFR-targeted cytotoxic drug.The novel EpCAM-targeting monoclonal antibody 3-17I linked to saporin is highly cytotoxic after photochemical internalization in breast, pancreas and colon cancer cell lines.Light directed gene transfer by photochemical internalisation.Light-controlled endosomal escape of the novel CD133-targeting immunotoxin AC133-saporin by photochemical internalization - A minimally invasive cancer stem cell-targeting strategy.Photochemical internalisation, a minimally invasive strategy for light-controlled endosomal escape of cancer stem cell-targeting therapeutics.Photochemical internalisation in drug and gene delivery.Epidermal growth factor receptor-targeted photosensitizer selectively inhibits EGFR signaling and induces targeted phototoxicity in ovarian cancer cellsPorphyrin-related photosensitizers for cancer imaging and therapeutic applications.Photochemical internalization (PCI): a new modality for light activation of endocytosed therapeuticals.Photochemical internalization: a new tool for drug delivery.Photochemical internalization (PCI) in cancer therapy: from bench towards bedside medicine.Photochemical internalization: a new tool for gene and oligonucleotide delivery.Photochemical disruption of endocytic vesicles before delivery of drugs: a new strategy for cancer therapy.Photochemical activation of drugs for the treatment of therapy-resistant cancers.Development of resistance to photodynamic therapy (PDT) in human breast cancer cells is photosensitizer-dependent: Possible mechanisms and approaches for overcoming PDT-resistance.Light-triggered, efficient cytosolic release of IM7-saporin targeting the putative cancer stem cell marker CD44 by photochemical internalization.Circumvention of resistance to photodynamic therapy in doxorubicin-resistant sarcoma by photochemical internalization of gelonin.Vascular endothelial cells as targets for photochemical internalization (PCI).Sustained ERK [corrected] inhibition by EGFR targeting therapies is a predictive factor for synergistic cytotoxicity with PDT as neoadjuvant therapy.Disulfonated tetraphenyl chlorin (TPCS2a), a novel photosensitizer developed for clinical utilization of photochemical internalization.Photochemical internalization (PCI): a technology for drug delivery.Photodynamic therapy targets the mTOR signaling network in vitro and in vivo.Y1068 phosphorylation is the most sensitive target of disulfonated tetraphenylporphyrin-based photodynamic therapy on epidermal growth factor receptor.Targeted delivery and enhanced cytotoxicity of cetuximab-saporin by photochemical internalization in EGFR-positive cancer cells.Photochemical internalization of therapeutic macromolecular agents: a novel strategy to kill multidrug-resistant cancer cells.Mechanistic investigation and implications of photodynamic therapy induction of vascular endothelial growth factor in prostate cancer.Photochemical internalization (PCI)--a novel technology for release of macromolecules from endocytic vesicles.Abstracts from the 4th ImmunoTherapy of Cancer Conference: Prague, Czech Republic. 20–22 March 2017.5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin.Photochemical Internalization of Peptide Antigens Provides a Novel Strategy to Realize Therapeutic Cancer Vaccination.Enhanced targeting of triple-negative breast carcinoma and malignant melanoma by photochemical internalization of CSPG4-targeting immunotoxins.Extracellular phospholipase A2 expression in sarcoidosisRelease of gelonin from endosomes and lysosomes to cytosol by photochemical internalizationPhotochemical internalisation increases the cytotoxic effect of the immunotoxin MOC31-geloninPhotochemical Internalization for Intracellular Drug Delivery. From Basic Mechanisms to Clinical Research
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Pål K Selbo
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Pål K Selbo
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Pål K Selbo
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Pål K Selbo
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Pål K Selbo
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Pål K Selbo
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Pål K Selbo
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P108
P106
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20149196250474790307
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0000-0002-5310-057X