about
The mammalian oxysterol-binding protein-related proteins (ORPs) bind 25-hydroxycholesterol in an evolutionarily conserved pocket1.8 and 1.9 A resolution structures of the Penicillium amagasakiense and Aspergillus niger glucose oxidases as a basis for modelling substrate complexesStructure-guided discovery of 1,3,5 tri-substituted benzenes as potent and selective matriptase inhibitors exhibiting in vivo antitumor efficacyRequirements for transcriptional regulation by the orphan nuclear receptor ERRgammaPositioning of anchor groups in protein loop prediction: the importance of solvent accessibility and secondary structure elements.Classification and comparison of ligand-binding sites derived from grid-mapped knowledge-based potentials.Novel small molecule inhibitors for prostate-specific antigen.Probing pH-dependent functional elements in proteins: modification of carboxylic acid pairs in Trichoderma reesei cellobiohydrolase Cel6A.The chemical mechanism of action of glucose oxidase from Aspergillus niger.A vertebrate model for the study of lipid binding/transfer protein function: conservation of OSBP-related proteins between zebrafish and human.Aspects of the mechanism of catalysis of glucose oxidase: a docking, molecular mechanics and quantum chemical study.Efficient methods for filtering and ranking fragments for the prediction of structurally variable regions in proteins.Field-based comparison of ligand and coactivator binding sites of nuclear receptors.Analysis of pH-dependent elements in proteins: geometry and properties of pairs of hydrogen-bonded carboxylic acid side-chainsODM-203 a selective inhibitor of FGFR and VEGFR, shows strong anti-tumor activity, and induces anti-tumor immunity3D proteochemometrics: using three-dimensional information of proteins and ligands to address aspects of the selectivity of serine proteases.
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description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Gerd Wohlfahrt
@ast
Gerd Wohlfahrt
@en
Gerd Wohlfahrt
@es
Gerd Wohlfahrt
@nl
Gerd Wohlfahrt
@sl
type
label
Gerd Wohlfahrt
@ast
Gerd Wohlfahrt
@en
Gerd Wohlfahrt
@es
Gerd Wohlfahrt
@nl
Gerd Wohlfahrt
@sl
prefLabel
Gerd Wohlfahrt
@ast
Gerd Wohlfahrt
@en
Gerd Wohlfahrt
@es
Gerd Wohlfahrt
@nl
Gerd Wohlfahrt
@sl
P106
P31
P496
0000-0003-0530-2000