Targeted disruption of heat shock transcription factor 1 abolishes thermotolerance and protection against heat-inducible apoptosis.
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The endoplasmic reticulum chaperone glycoprotein GRP94 with Ca(2+)-binding and antiapoptotic properties is a novel proteolytic target of calpain during etoposide-induced apoptosisHsp72-mediated suppression of c-Jun N-terminal kinase is implicated in development of tolerance to caspase-independent cell deathPhosphorylation of HSF1 by MAPK-activated protein kinase 2 on serine 121, inhibits transcriptional activity and promotes HSP90 bindingA novel HSF1-mediated death pathway that is suppressed by heat shock proteinsAssociation and regulation of heat shock transcription factor 4b with both extracellular signal-regulated kinase mitogen-activated protein kinase and dual-specificity tyrosine phosphatase DUSP26Aging as an event of proteostasis collapseHeat shock factor 1 is a powerful multifaceted modifier of carcinogenesisPhosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1Analysis of phosphorylation of human heat shock factor 1 in cells experiencing a stressNutritional interventions to alleviate the negative consequences of heat stressROS stress resets circadian clocks to coordinate pro-survival signalsDefining the Essential Function of Yeast Hsf1 Reveals a Compact Transcriptional Program for Maintaining Eukaryotic Proteostasis.DAXX interacts with heat shock factor 1 during stress activation and enhances its transcriptional activityRegulation of molecular chaperone gene transcription involves the serine phosphorylation, 14-3-3 epsilon binding, and cytoplasmic sequestration of heat shock factor 1Regulation of heat shock transcription factor 1 by stress-induced SUMO-1 modificationmTOR is essential for the proteotoxic stress response, HSF1 activation and heat shock protein synthesisUncoupling Stress-Inducible Phosphorylation of Heat Shock Factor 1 from Its ActivationHeat and heavy metal stress synergize to mediate transcriptional hyperactivation by metal-responsive transcription factor MTF-1Heat shock factor 1 represses transcription of the IL-1beta gene through physical interaction with the nuclear factor of interleukin 6The mouse polyubiquitin gene UbC is essential for fetal liver development, cell-cycle progression and stress toleranceCHIP-mediated stress recovery by sequential ubiquitination of substrates and Hsp70Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1Expression of inducible Hsp70 enhances the proliferation of MCF-7 breast cancer cells and protects against the cytotoxic effects of hyperthermiaThe loop domain of heat shock transcription factor 1 dictates DNA-binding specificity and responses to heat stressHyperthermia promotes and prevents respiratory epithelial apoptosis through distinct mechanismsHeat shock protein 70 inhibits hydrogen peroxide-induced nucleolar fragmentation via suppressing cleavage and down-regulation of nucleolinRiluzole increases the amount of latent HSF1 for an amplified heat shock response and cytoprotectionAnalysis of HSF4 binding regions reveals its necessity for gene regulation during development and heat shock response in mouse lensesIdentification of heat shock factor 1 molecular and cellular targets during embryonic and adult female meiosisThe master regulator of the cellular stress response (HSF1) is critical for orthopoxvirus infectionDevelopmentally dictated expression of heat shock factors: exclusive expression of HSF4 in the postnatal lens and its specific interaction with alphaB-crystallin heat shock promoterHeat stress activates ER stress signals which suppress the heat shock response, an effect occurring preferentially in the cortex in ratsHSF4 is required for normal cell growth and differentiation during mouse lens developmentInteraction of HSF1 and HSF2 with the Hspa1b promoter in mouse epididymal spermatozoaA novel mouse HSF3 has the potential to activate nonclassical heat-shock genes during heat shockTranscriptional regulation and binding of heat shock factor 1 and heat shock factor 2 to 32 human heat shock genes during thermal stress and differentiation.Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and agingPolymorphisms in human heat shock factor-1 and analysis of potential biological consequences.Celastrol inhibits aminoglycoside-induced ototoxicity via heat shock protein 32.Heat shock factor 1 regulates lifespan as distinct from disease onset in prion disease.
P2860
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P2860
Targeted disruption of heat shock transcription factor 1 abolishes thermotolerance and protection against heat-inducible apoptosis.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Targeted disruption of heat sh ...... inst heat-inducible apoptosis.
@en
Targeted disruption of heat sh ...... inst heat-inducible apoptosis.
@nl
type
label
Targeted disruption of heat sh ...... inst heat-inducible apoptosis.
@en
Targeted disruption of heat sh ...... inst heat-inducible apoptosis.
@nl
prefLabel
Targeted disruption of heat sh ...... inst heat-inducible apoptosis.
@en
Targeted disruption of heat sh ...... inst heat-inducible apoptosis.
@nl
P2093
P356
P1476
Targeted disruption of heat sh ...... inst heat-inducible apoptosis.
@en
P2093
P304
P356
10.1074/JBC.273.13.7523
P407
P577
1998-03-01T00:00:00Z