Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.
about
Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent mannerCleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosisIdentification of the cytolinker plectin as a major early in vivo substrate for caspase 8 during CD95- and tumor necrosis factor receptor-mediated apoptosisInhibition of Daxx-mediated apoptosis by heat shock protein 27FLASH links the CD95 signaling pathway to the cell nucleus and nuclear bodiesA20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells.Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8.Suppression of caspase-8- and -10-associated RING proteins results in sensitization to death ligands and inhibition of tumor cell growthFLICE-inhibitory proteins: regulators of death receptor-mediated apoptosisCaspase-resistant BAP31 inhibits fas-mediated apoptotic membrane fragmentation and release of cytochrome c from mitochondriaNF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosisLoss of Daxx, a promiscuously interacting protein, results in extensive apoptosis in early mouse developmentThe Fas-associated death domain protein is required in apoptosis and TLR-induced proliferative responses in B cellsRipped to deathFADD and caspase-8 control the outcome of autophagic signaling in proliferating T cellsEvidence for a Novel, Caspase-8-Independent, Fas Death Domain-Mediated Apoptotic PathwayCytokine and anti-cytokine therapies in prevention or treatment of fibrosis in IBDNecroptosis in acute kidney injury: a shedding lightConverging roles of caspases in inflammasome activation, cell death and innate immunityNecroptotic Cell Death Signaling and Execution Pathway: Lessons from Knockout MiceDED or alive: assembly and regulation of the death effector domain complexesRegulation of CD95/Fas signaling at the DISCPhotoreceptor cell death and rescue in retinal detachment and degenerationsThe two faces of receptor interacting protein kinase-1Historical perspectives on tumor necrosis factor and its superfamily: 25 years later, a golden journeyCaspase-8 as a regulator of tumor cell motilityViral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathwaysNecroptosis: molecular signalling and translational implicationsRegulated necrotic cell death: the passive aggressive side of Bax and BakRIPK-dependent necrosis and its regulation by caspases: a mystery in five actsExecutioner Caspase-3 and 7 Deficiency Reduces Myocyte Number in the Developing Mouse HeartOxidative stress, unfolded protein response, and apoptosis in developmental toxicityFrequent nuclear localization of ICAD and cytoplasmic co-expression of caspase-8 and caspase-3 in human lymphomasCaspase-8 activation and bid cleavage contribute to MCF7 cellular execution in a caspase-3-dependent manner during staurosporine-mediated apoptosisCIS3/SOCS-3 suppresses erythropoietin (EPO) signaling by binding the EPO receptor and JAK2TL1A-induced NF-kappaB activation and c-IAP2 production prevent DR3-mediated apoptosis in TF-1 cellsDeath receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8Caspase-2-induced apoptosis is dependent on caspase-9, but its processing during UV- or tumor necrosis factor-dependent cell death requires caspase-3PAK4 kinase is essential for embryonic viability and for proper neuronal developmentCaspases: opening the boxes and interpreting the arrows
P2860
Q22008727-9655CC60-C29A-4D4F-86B0-C2F301998BD6Q22010649-BABE7E5A-8E8A-4D19-BFE8-D97E43669214Q22254599-EDEBD8F3-63F3-4FCD-B482-70CF9DE8012CQ24290301-D8724E56-DDD4-41E8-94AD-F997D10B696EQ24294356-9B6741B6-486A-49F1-B69F-B68785FB0F0CQ24304048-1EBF6C0D-4027-4B74-A6ED-227C19B5EC5BQ24305298-9F458653-2891-4D61-9714-6F50F534D2BDQ24328839-7FF59155-0E9D-43D3-AB73-0BF5F3241F5BQ24548247-0A4BC015-EE5E-4532-89C7-69AE4FAADC50Q24551487-A859A785-C1F8-40F9-8808-53D1F6C966B3Q24554454-FAB0A57A-8DD2-42A8-893F-FA2B01E79F36Q24600961-26229168-C84A-483A-8240-6587EF3B3A45Q24621785-38F96509-365A-4218-A195-D4BCF1CB7FD5Q24632980-A500898F-9986-4E4A-ACB3-C21BB84658CAQ24646372-09AB85F0-36B9-412F-A066-3BB1193ACAE2Q24809567-D854FAEB-452B-42FC-A6BC-1C24BDED35D0Q26740540-57EAF32F-E5C7-4ED7-85E4-F18FB5CD65E6Q26764791-6867F719-B2B2-46F5-8698-9A028DE2DE0DQ26776532-4A4A1F1A-D026-457A-89CD-1B73F5E9F96EQ26778547-480A506A-0807-46B9-B082-EC29C7911D4FQ26796544-249AB5BC-7D14-4B5F-B36F-0A67662240AAQ26824629-F81AE9D0-5D87-4D72-92F6-65390BA1358CQ26853192-F9F993E5-A799-424C-92EB-5D64E962EC79Q26853682-093EE050-A497-416B-95FD-B4CEB5A02080Q26991848-207F8A97-144E-49A5-9A94-3B4C54134558Q26996626-7214011F-2555-4C08-8E59-C1F9A0495DEBQ27010127-FF4EA368-25D6-4D37-8052-F0AD56217763Q27015896-E2B92355-024F-45CE-B76A-85456B9A90FAQ27021740-C4AFC877-084E-40A4-8365-00ADB795783AQ27026600-7809700D-A510-471E-9993-9F572A12A384Q27303642-24CCAE49-25BC-44D6-AAE4-26DA9BD6371CQ28084613-D9A781C1-4BCB-433B-BE24-B4360E7629C6Q28139595-01E8E115-C1F5-49B4-95C2-4649AB4A15E3Q28139667-F87E2E8F-6DA7-438A-A607-C6F3062D4929Q28140132-D05DBADB-6115-4A78-BA1A-7571C4297D9EQ28189886-E918BF99-E9DE-4401-80E4-194C54DDED42Q28189969-81E2F01A-B665-4844-A294-E8CB8EBC52E1Q28201157-9117636B-F1BD-4E84-B42E-DFAABB7568BAQ28205608-2339640A-CC0D-468A-998D-6B3422C3DE1DQ28216089-9C22F993-B0DA-44D2-9FD6-7D80B9D0A70C
P2860
Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Targeted disruption of the mou ...... DR3 and is lethal prenatally.
@en
Targeted disruption of the mou ...... DR3 and is lethal prenatally.
@nl
type
label
Targeted disruption of the mou ...... DR3 and is lethal prenatally.
@en
Targeted disruption of the mou ...... DR3 and is lethal prenatally.
@nl
prefLabel
Targeted disruption of the mou ...... DR3 and is lethal prenatally.
@en
Targeted disruption of the mou ...... DR3 and is lethal prenatally.
@nl
P2093
P1433
P1476
Targeted disruption of the mou ...... DR3 and is lethal prenatally.
@en
P2093
Avraham KB
Beckmann JS
Brodianski VM
Chiannilkulchai N
Goncharov T
Holtmann H
P304
P356
10.1016/S1074-7613(00)80609-3
P407
P577
1998-08-01T00:00:00Z