Mice with a targeted disruption of the H1t gene are fertile and undergo normal changes in structural chromosomal proteins during spermiogenesis.
about
Polar nuclear localization of H1T2, a histone H1 variant, required for spermatid elongation and DNA condensation during spermiogenesisHILS1 is a spermatid-specific linker histone H1-like protein implicated in chromatin remodeling during mammalian spermiogenesisHistone variants: are they functionally heterogeneous?Epigenetic regulation of the histone-to-protamine transition during spermiogenesisThe histone H1 family: specific members, specific functions?H1 linker histones are essential for mouse development and affect nucleosome spacing in vivoTagged mutagenesis by efficient Minos-based germ line transpositionRFX2 is a candidate downstream amplifier of A-MYB regulation in mouse spermatogenesis.Individual somatic H1 subtypes are dispensable for mouse development even in mice lacking the H1(0) replacement subtype.Human testis/sperm-specific histone H2B (hTSH2B). Molecular cloning and characterization.Targeted disruption of the testicular SPAG5/deepest protein does not affect spermatogenesis or fertility.RFX2 is a potential transcriptional regulatory factor for histone H1t and other genes expressed during the meiotic phase of spermatogenesis.Effects of L- and T-type Ca²(+) channel blockers on spermatogenesis and steroidogenesis in the prepubertal mouse testisTargeted disruption of the mouse testis-enriched gene Znf230 does not affect spermatogenesis or fertilityPoly(ADP-ribose) metabolism is essential for proper nucleoprotein exchange during mouse spermiogenesisThe role of H1 linker histone subtypes in preserving the fidelity of elaboration of mesendodermal and neuroectodermal lineages during embryonic developmentHistone H1 and the dynamic regulation of chromatin function.Local compartment changes and regulatory landscape alterations in histone H1-depleted cellsDifferential expression of Rfx1-4 during mouse spermatogenesis.The role of the double bromodomain-containing BET genes during mammalian spermatogenesis.Histone variants and sensing of chromatin functional states.Role of H1 linker histones in mammalian development and stem cell differentiation.Characterization of the H1t promoter: role of conserved histone 1 AC and TG elements and dominance of the cap-proximal silencer.Testis-specific linker histone H1t is multiply phosphorylated during spermatogenesis. Identification of phosphorylation sites.Reductions in linker histone levels are tolerated in developing spermatocytes but cause changes in specific gene expression.MAFB is dispensable for the fetal testis morphogenesis and the maintenance of spermatogenesis in adult mice.A K52Q substitution in the globular domain of histone H1t modulates its nucleosome binding properties
P2860
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P2860
Mice with a targeted disruption of the H1t gene are fertile and undergo normal changes in structural chromosomal proteins during spermiogenesis.
description
2001 nî lūn-bûn
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2001年の論文
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2001年学术文章
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2001年学术文章
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2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
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2001年學術文章
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name
Mice with a targeted disruptio ...... roteins during spermiogenesis.
@en
Mice with a targeted disruptio ...... roteins during spermiogenesis.
@nl
type
label
Mice with a targeted disruptio ...... roteins during spermiogenesis.
@en
Mice with a targeted disruptio ...... roteins during spermiogenesis.
@nl
prefLabel
Mice with a targeted disruptio ...... roteins during spermiogenesis.
@en
Mice with a targeted disruptio ...... roteins during spermiogenesis.
@nl
P2093
P2860
P1476
Mice with a targeted disruptio ...... roteins during spermiogenesis.
@en
P2093
P2860
P304
P356
10.1095/BIOLREPROD64.2.425
P407
P577
2001-02-01T00:00:00Z