The immunophilin FKBP12 functions as a common inhibitor of the TGF beta family type I receptors.
about
Direct interaction between Smad3, APC10, CDH1 and HEF1 in proteasomal degradation of HEF1Transforming growth factor-beta receptor-associated protein 1 is a Smad4 chaperoneReceptor accessory folding helper enzymes: the functional role of peptidyl prolyl cis/trans isomerasesA recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressivaA novel protein distinguishes between quiescent and activated forms of the type I transforming growth factor beta receptorRapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells.Bone morphogenetic protein receptor complexes on the surface of live cells: a new oligomerization mode for serine/threonine kinase receptorsTLP, a novel modulator of TGF-beta signaling, has opposite effects on Smad2- and Smad3-dependent signalingStructure of the bone morphogenetic protein receptor ALK2 and implications for fibrodysplasia ossificans progressivaInterconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2The 13-kD FK506 binding protein, FKBP13, interacts with a novel homologue of the erythrocyte membrane cytoskeletal protein 4.1Overactive bone morphogenetic protein signaling in heterotopic ossification and Duchenne muscular dystrophyHigh-resolution crystal structure of FKBP12 from Aedes aegyptiSmall molecule Plasmodium FKBP35 inhibitor as a potential antimalaria agentStructural basis of conformational transitions in the active site and 80′s loop in the FK506-binding protein FKBP12Crystal structure of Plasmodium vivax FK506-binding protein 25 reveals conformational changes responsible for its noncanonical activityFAP1, a homologue of human transcription factor NF-X1, competes with rapamycin for binding to FKBP12 in yeast.Hmo1p, a high mobility group 1/2 homolog, genetically and physically interacts with the yeast FKBP12 prolyl isomeraseFKBP12 binds the inositol 1,4,5-trisphosphate receptor at leucine-proline (1400-1401) and anchors calcineurin to this FK506-like domainGenomic structure and chromosomal location of the human TGFbeta-receptor interacting protein-1 (TRIP-1) gene to 1p34.1BRAM1, a BMP receptor-associated molecule involved in BMP signallingThe Discovery and Early Days of TGF-β: A Historical PerspectiveLumican binds ALK5 to promote epithelium wound healingA fresh look at augmenter of liver regeneration in ratsBMP10 is essential for maintaining cardiac growth during murine cardiogenesisCardiac defects and altered ryanodine receptor function in mice lacking FKBP12TGF beta 1 inhibits Ca2+-calcineurin-mediated activation in thymocytesReversible inhibition of calcineurin by the polyphenolic aldehyde gossypol.Mutational analysis of the ACVR1 gene in Italian patients affected with fibrodysplasia ossificans progressiva: confirmations and advancements.Critical roles of miRNA-mediated regulation of TGFβ signalling during mouse cardiogenesis.FK506 nephrotoxicity.A kinase subdomain of transforming growth factor-beta (TGF-beta) type I receptor determines the TGF-beta intracellular signaling specificity.Role of TAK1 and TAB1 in BMP signaling in early Xenopus developmentMolecular consequences of the ACVR1(R206H) mutation of fibrodysplasia ossificans progressiva.The FOP metamorphogene encodes a novel type I receptor that dysregulates BMP signaling.Neuroimmunophilins: novel neuroprotective and neuroregenerative targets.FKBP12, the 12-kDa FK506-binding protein, is a physiologic regulator of the cell cycle.ALK5 and ALK1 play antagonistic roles in transforming growth factor β-induced podosome formation in aortic endothelial cells.Distinctive mechanism for sustained TGF-β signaling and growth inhibition: MEK1 activation-dependent stabilization of type II TGF-β receptors.FK506 binding protein 12 deficiency in endothelial and hematopoietic cells decreases regulatory T cells and causes hypertension.
P2860
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P2860
The immunophilin FKBP12 functions as a common inhibitor of the TGF beta family type I receptors.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh-hant
name
The immunophilin FKBP12 functi ...... beta family type I receptors.
@en
The immunophilin FKBP12 functi ...... beta family type I receptors.
@nl
type
label
The immunophilin FKBP12 functi ...... beta family type I receptors.
@en
The immunophilin FKBP12 functi ...... beta family type I receptors.
@nl
prefLabel
The immunophilin FKBP12 functi ...... beta family type I receptors.
@en
The immunophilin FKBP12 functi ...... beta family type I receptors.
@nl
P2093
P1433
P1476
The immunophilin FKBP12 functi ...... beta family type I receptors.
@en
P2093
Danielson PD
Donahoe PK
Lechleider RJ
Manganaro T
Rockwell S
P304
P356
10.1016/S0092-8674(00)80116-6
P407
P577
1996-08-01T00:00:00Z