Gap junctional communication modulates gene transcription by altering the recruitment of Sp1 and Sp3 to connexin-response elements in osteoblast promoters.
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Connexins: a myriad of functions extending beyond assembly of gap junction channelsGenomic approaches to identifying transcriptional regulators of osteoblast differentiationGap junctional regulation of signal transduction in bone cellsInteraction of connexin43 and protein kinase C-delta during FGF2 signalingHeterogeneous nuclear ribonucleoprotein K represses transcription from a cytosine/thymidine-rich element in the osteocalcin promoterOsteoblast connexin43 modulates skeletal architecture by regulating both arms of bone remodelingThe connexin43-interacting protein, CIP85, mediates the internalization of connexin43 from the plasma membrane.The gap junction protein connexin32 interacts with the Src homology 3/hook domain of discs large homolog 1.Beta-catenin and BMP-2 synergize to promote osteoblast differentiation and new bone formation.Sp1/Sp3 and DNA-methylation contribute to basal transcriptional activation of human podoplanin in MG63 versus Saos-2 osteoblastic cellsGap junctions regulate extracellular signal-regulated kinase signaling to affect gene transcription.Interleukin-1beta increases gap junctional communication among synovial fibroblasts via the extracellular-signal-regulated kinase pathway.N-cadherin and cadherin 11 modulate postnatal bone growth and osteoblast differentiation by distinct mechanisms.Enhanced osteoclastic resorption and responsiveness to mechanical load in gap junction deficient bone.Changes in gap junction expression and function following ischemic injury of spinal cord white matterGap junction intercellular communication: a review of a potential platform to modulate craniofacial tissue engineering.Connexin 43 as a signaling platform for increasing the volume and spatial distribution of regenerated tissue.Identification of shoulder osteoarthritis biomarkers: comparison between shoulders with and without osteoarthritis.Hapln1a is required for connexin43-dependent growth and patterning in the regenerating fin skeleton.The transcriptional activity of osterix requires the recruitment of Sp1 to the osteocalcin proximal promoter.Cell autonomous requirement of connexin 43 for osteocyte survival: consequences for endocortical resorption and periosteal bone formation.miR-23a impairs bone differentiation in osteosarcoma via down-regulation of GJA1.Connexins and pannexins in the skeleton: gap junctions, hemichannels and moreERK acts in parallel to PKCδ to mediate the connexin43-dependent potentiation of Runx2 activity by FGF2 in MC3T3 osteoblasts.Proteomic Analysis of Connexin 43 Reveals Novel Interactors Related to Osteoarthritis.Gap junctions and hemichannels in signal transmission, function and development of boneGap junctions and hemichannels: communicating cell death in neurodevelopment and diseaseInteracting Network of the Gap Junction (GJ) Protein Connexin43 (Cx43) is Modulated by Ischemia and Reperfusion in the Heart.Beyond gap junctions: Connexin43 and bone cell signalingGap junctional communication in morphogenesis.Connexins in the skeletonCell-cell communication in the osteoblast/osteocyte lineage.Cooperative activation of tissue-specific genes by pRB and E2F1.Regulation of the bone-restricted IFITM-like (Bril) gene transcription by Sp and Gli family members and CpG methylation.The regulation of runt-related transcription factor 2 by fibroblast growth factor-2 and connexin43 requires the inositol polyphosphate/protein kinase Cδ cascadeConnexin 43 deficiency attenuates loss of trabecular bone and prevents suppression of cortical bone formation during unloading.Co-stimulation of the bone-related Runx2 P1 promoter in mesenchymal cells by SP1 and ETS transcription factors at polymorphic purine-rich DNA sequences (Y-repeats)Array analysis of gene expression in connexin-43 null astrocytes.Attenuated response to in vivo mechanical loading in mice with conditional osteoblast ablation of the connexin43 gene (Gja1).Connexin43 potentiates osteoblast responsiveness to fibroblast growth factor 2 via a protein kinase C-delta/Runx2-dependent mechanism
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P2860
Gap junctional communication modulates gene transcription by altering the recruitment of Sp1 and Sp3 to connexin-response elements in osteoblast promoters.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Gap junctional communication m ...... ments in osteoblast promoters.
@en
Gap junctional communication m ...... ments in osteoblast promoters.
@nl
type
label
Gap junctional communication m ...... ments in osteoblast promoters.
@en
Gap junctional communication m ...... ments in osteoblast promoters.
@nl
prefLabel
Gap junctional communication m ...... ments in osteoblast promoters.
@en
Gap junctional communication m ...... ments in osteoblast promoters.
@nl
P2093
P2860
P356
P1476
Gap junctional communication m ...... ements in osteoblast promoters
@en
P2093
Joanne Screen
Joseph P Stains
Roberto Civitelli
P2860
P304
24377-24387
P356
10.1074/JBC.M212554200
P407
P577
2003-04-16T00:00:00Z