Differential endocytic sorting of p75NTR and TrkA in response to NGF: a role for late endosomes in TrkA trafficking.
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Differential effects of myopathy-associated caveolin-3 mutants on growth factor signalingRap1-PDZ-GEF1 interacts with a neurotrophin receptor at late endosomes, leading to sustained activation of Rap1 and ERK and neurite outgrowthRegulation of trafficking of activated TrkA is critical for NGF-mediated functionsCharcot-Marie-Tooth disease and intracellular trafficAttractive axon guidance involves asymmetric membrane transport and exocytosis in the growth coneNeurotrophins Redirect p75NTR from a clathrin-independent to a clathrin-dependent endocytic pathway coupled to axonal transportThe protein phosphatase 2A regulatory subunits B'beta and B'delta mediate sustained TrkA neurotrophin receptor autophosphorylation and neuronal differentiationHigh-resolution fractionation of signaling endosomes containing different receptorsAxonal targeting of Trk receptors via transcytosis regulates sensitivity to neurotrophin responsesFates of neurotrophins after retrograde axonal transport: phosphorylation of p75NTR is a sorting signal for delayed degradationSyntaxin 8 modulates the post-synthetic trafficking of the TrkA receptor and inflammatory pain transmission.Directing traffic in neural cells: determinants of receptor tyrosine kinase localization and cellular responses.A novel endocytic recycling signal distinguishes biological responses of Trk neurotrophin receptors.NGF causes TrkA to specifically attract microtubules to lipid rafts.Three-dimensional distribution of TrkA neurotrophin receptors in neurite varicosities of differentiated PC12 cells treated with NGF determined by immunoelectron tomography.Multivesicular bodies in neurons: distribution, protein content, and trafficking functions.LAMTOR2-mediated modulation of NGF/MAPK activation kinetics during differentiation of PC12 cellsPro-NGF from Alzheimer's disease and normal human brain displays distinctive abilities to induce processing and nuclear translocation of intracellular domain of p75NTR and apoptosis.GGA3 mediates TrkA endocytic recycling to promote sustained Akt phosphorylation and cell survival.Metalloproteases and gamma-secretase: new membrane partners regulating p75 neurotrophin receptor signaling?Paradigm shifts in the cell biology of STAT signalingThe p75 neurotrophin receptor evades the endolysosomal route in neuronal cells, favouring multivesicular bodies specialised for exosomal releaseThe role of rab proteins in neuronal cells and in the trafficking of neurotrophin receptors.Essential role of Hrs in endocytic recycling of full-length TrkB receptor but not its isoform TrkB.T1.Inhibition of Abl tyrosine kinase enhances nerve growth factor-mediated signaling in Bcr-Abl transformed cells via the alteration of signaling complex and the receptor turnover.Membrane-associated STAT3 and PY-STAT3 in the cytoplasm.The STAT3 beacon: IL-6 recurrently activates STAT 3 from endosomal structuresDifferential effects of BDNF and neurotrophin 4 (NT4) on endocytic sorting of TrkB receptors.TrkA receptor endolysosomal degradation is both ubiquitin and proteasome dependent.Tyr-701 is a new regulatory site for neurotrophin receptor TrkA trafficking and function.
P2860
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P2860
Differential endocytic sorting of p75NTR and TrkA in response to NGF: a role for late endosomes in TrkA trafficking.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
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2005年學術文章
@zh-hant
name
Differential endocytic sorting ...... endosomes in TrkA trafficking.
@en
Differential endocytic sorting ...... endosomes in TrkA trafficking.
@nl
type
label
Differential endocytic sorting ...... endosomes in TrkA trafficking.
@en
Differential endocytic sorting ...... endosomes in TrkA trafficking.
@nl
prefLabel
Differential endocytic sorting ...... endosomes in TrkA trafficking.
@en
Differential endocytic sorting ...... endosomes in TrkA trafficking.
@nl
P2093
P50
P1476
Differential endocytic sorting ...... endosomes in TrkA trafficking.
@en
P2093
Alex Krüttgen
Harald Hirling
Joachim Weis
Jonah R Chan
Pascal Steiner
P304
P356
10.1016/J.MCN.2004.11.011
P577
2005-03-01T00:00:00Z