Differential involvement of BB loops of toll-IL-1 resistance (TIR) domain-containing adapter proteins in TLR4- versus TLR2-mediated signal transduction.
about
Analysis of proteinase-activated receptor 2 and TLR4 signal transduction: a novel paradigm for receptor cooperativityMyD88-dependent and -independent signaling by IL-1 in neurons probed by bifunctional Toll/IL-1 receptor domain/BB-loop mimetics.The crystal structure of the human toll-like receptor 10 cytoplasmic domain reveals a putative signaling dimerCrystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protectionMolecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coliStructural Insights into TIR Domain Specificity of the Bridging Adaptor Mal in TLR4 SignalingDetails of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis.A dimer of the Toll-like receptor 4 cytoplasmic domain provides a specific scaffold for the recruitment of signalling adaptor proteinsPhagosomal retention of Francisella tularensis results in TIRAP/Mal-independent TLR2 signaling.The HMGB1-RAGE axis mediates traumatic brain injury-induced pulmonary dysfunction in lung transplantation.Targeting TLR4 signaling by TLR4 Toll/IL-1 receptor domain-derived decoy peptides: identification of the TLR4 Toll/IL-1 receptor domain dimerization interface.Leukocyte- and platelet-derived microvesicle interactions following in vitro and in vivo activation of toll-like receptor 4 by lipopolysaccharide.Targeting Toll-like receptor (TLR) signaling by Toll/interleukin-1 receptor (TIR) domain-containing adapter protein/MyD88 adapter-like (TIRAP/Mal)-derived decoy peptides.Inhibition of TLR4 signaling by TRAM-derived decoy peptides in vitro and in vivoTrif-dependent induction of Th17 immunity by lung dendritic cellsActivation of lymphoma-associated MyD88 mutations via allostery-induced TIR-domain oligomerization.Overexpression of the toll-like receptor (TLR) signaling adaptor MYD88, but lack of genetic mutation, in myelodysplastic syndromes.Characteristic and functional analysis of toll-like receptors (TLRs) in the lophotrocozoan, Crassostrea gigas, reveals ancient origin of TLR-mediated innate immunityScavenger receptor SREC-I mediated entry of TLR4 into lipid microdomains and triggered inflammatory cytokine release in RAW 264.7 cells upon LPS activationA Decoy Peptide that Disrupts TIRAP Recruitment to TLRs Is Protective in a Murine Model of InfluenzaTRAF6 protein couples Toll-like receptor 4 signaling to Src family kinase activation and opening of paracellular pathway in human lung microvascular endothelia.TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice.Exogenous tumour necrosis factor alpha induces suppression of autoimmune arthritisToll/interleukin-1 receptor domain-containing adapter inducing interferon-β mediates microglial phagocytosis of degenerating axons.Modulation of microtubule dynamics by a TIR domain protein from the intracellular pathogen Brucella melitensis.Paediatric obstructive sleep apnoea syndrome (OSAS) is associated with tonsil colonisation by Streptococcus pyogenesSuppression of TLR signaling by targeting TIR domain-containing proteinsCell-penetrating TIR BB loop decoy peptides a novel class of TLR signaling inhibitors and a tool to study topology of TIR-TIR interactions.Structure, function and regulation of the Toll/IL-1 receptor adaptor proteins.TLR4-mediated activation of dendritic cells by the heat shock protein DnaK from Francisella tularensis.Functional cell permeable motifs within medically relevant proteins.Tolerization with Hsp65 induces protection against adjuvant-induced arthritis by modulating the antigen-directed interferon-gamma, interleukin-17, and antibody responsesTLR4/MyD88/PI3K interactions regulate TLR4 signaling.Human TLR8 is activated upon recognition of Borrelia burgdorferi RNA in the phagosome of human monocytesPeptides modulating conformational changes in secreted chaperones: from in silico design to preclinical proof of concept.Recruitment of TLR adapter TRIF to TLR4 signaling complex is mediated by the second helical region of TRIF TIR domain.Structure and regulation of cytoplasmic adapter proteins involved in innate immune signaling.Targeting TLR/IL-1R signalling in human diseases.Prophylactic and therapeutic implications of toll-like receptor ligands.Toll/interleukin-1 receptor (TIR) domain-mediated cellular signaling pathways.
P2860
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P2860
Differential involvement of BB loops of toll-IL-1 resistance (TIR) domain-containing adapter proteins in TLR4- versus TLR2-mediated signal transduction.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Differential involvement of BB ...... -mediated signal transduction.
@en
Differential involvement of BB loops of toll-IL-1 resistance
@nl
type
label
Differential involvement of BB ...... -mediated signal transduction.
@en
Differential involvement of BB loops of toll-IL-1 resistance
@nl
prefLabel
Differential involvement of BB ...... -mediated signal transduction.
@en
Differential involvement of BB loops of toll-IL-1 resistance
@nl
P2093
P1476
Differential involvement of BB ...... -mediated signal transduction.
@en
P2093
Matthew J Fenton
Stefanie N Vogel
Subhendu Basu
Vladimir U Toshchakov
P304
P356
10.4049/JIMMUNOL.175.1.494
P407
P577
2005-07-01T00:00:00Z