Three classes of inhibitors share a common binding domain in mitochondrial complex I (NADH:ubiquinone oxidoreductase).
about
Human ind1, an iron-sulfur cluster assembly factor for respiratory complex ISupercomplexes in the respiratory chains of yeast and mammalian mitochondriaThe ND2 subunit is labeled by a photoaffinity analogue of asimicin, a potent complex I inhibitorMitochondrial Redox Dysfunction and Environmental ExposuresStructural biology. Mechanistic insight from the crystal structure of mitochondrial complex IAn anthelmintic compound, nafuredin, shows selective inhibition of complex I in helminth mitochondria.Mutations in the complex I NDUFS2 gene of patients with cardiomyopathy and encephalomyopathyMitochondrial reactive oxygen species production in excitable cells: modulators of mitochondrial and cell function.Data mining of NCI's anticancer screening database reveals mitochondrial complex I inhibitors cytotoxic to leukemia cell lines.Lidocaine depolarizes the mitochondrial membrane potential by intracellular alkalization in rat dorsal root ganglion neurons.Mitochondrial-Targeted Molecular Imaging in Cardiac DiseaseCellular oxygen sensing by mitochondria: old questions, new insight.Inhibitors of the quinone-binding site allow rapid superoxide production from mitochondrial NADH:ubiquinone oxidoreductase (complex I).Structural and biochemical characterization of a quinol binding site of Escherichia coli nitrate reductase A.Potential therapeutic benefits of strategies directed to mitochondria.Glutaredoxin 2 prevents H(2)O(2)-induced cell apoptosis by protecting complex I activity in the mitochondria.Azole susceptibility and transcriptome profiling in Candida albicans mitochondrial electron transport chain complex I mutants.Proton pumping by NADH:ubiquinone oxidoreductase. A redox driven conformational change mechanism?Synthesis and characterization of new piperazine-type inhibitors for mitochondrial NADH-ubiquinone oxidoreductase (complex I).A conserved lysine residue controls iron-sulfur cluster redox chemistry in Escherichia coli fumarate reductase.Vanilloids in pancreatic cancer: potential for chemotherapy and pain management.NADH-quinone oxidoreductase: PSST subunit couples electron transfer from iron-sulfur cluster N2 to quinone.Genome Analysis of Structure-Function Relationships in Respiratory Complex I, an Ancient Bioenergetic EnzymeTotal synthesis of piericidin A1 and B1.Total synthesis of piericidin A1 and B1 and key analoguesFetal programming alters reactive oxygen species production in sheep cardiac mitochondria.Smoking habits and coenzyme Q10 status in healthy European adults.Architecture of complex I and its implications for electron transfer and proton pumping.N-acetylcysteine inhibits post-impact chondrocyte death in osteochondral explantsBullatacin triggered ABCB1-overexpressing cell apoptosis via the mitochondrial-dependent pathway.The effects of pyridaben pesticide on the histomorphometric, hormonal alternations and reproductive functions of BALB/c mice.The effects of pyridaben pesticide on the DNA integrity of sperms and early in vitro embryonic development in mice.Piericidin A1 Blocks Yersinia Ysc Type III Secretion System Needle Assembly.Strategies for therapeutic hypometabothermiaA conserved amphipathic ligand binding region influences k-path-dependent activity of cytochrome C oxidase.Deguelin and Its Role in Chronic Diseases.Inhibitory effect of palmitate on the mitochondrial NADH:ubiquinone oxidoreductase (complex I) as related to the active-de-active enzyme transition.Silibinin induces protective superoxide generation in human breast cancer MCF-7 cells.mt-Nd2a suppresses reactive oxygen species production by mitochondrial complexes I and III.The responses of HT22 cells to the blockade of mitochondrial complexes and potential protective effect of selenium supplementation.
P2860
Q24315990-DE41A09A-8089-4946-BA35-01D7AB486BF7Q24599994-E57E5CB1-3A5B-4B7D-A556-EBABE6E9CF89Q24629912-CA23E60E-8889-40F6-8AA2-F8BD243C868AQ26863605-EE7DD6DD-4B57-42D6-8A60-46F33130F4C2Q27697274-CA56BD5A-07FC-4C82-9F89-46C95F045F1BQ28345186-B4DD7AD1-494A-4FBA-8069-73FE7134D8BDQ28646237-AE04CB5F-3425-490A-8897-8A12DBDA67A2Q30374674-7BE06102-0C48-475C-A236-2AE8F86C80B6Q31077911-E037EEC0-F4C5-48E9-80BB-CDFE2DEF7055Q33787983-CAA6CDDE-1B7D-400C-9FE9-243AB138EB76Q33790688-FDC61E91-D38F-40F9-9C9D-0FFF897297D2Q33910357-87AE7623-0FA7-4642-A2BC-6F2AFF647730Q33980059-3C8F5EA3-35CF-4E59-841B-43053DE407CEQ33983981-67E4B99A-84BF-4AEA-A3F5-17899D42020FQ34117168-5FD312E3-2AE0-4117-8754-F9DD0D77B7F7Q34120771-D30196E6-019B-4D4A-A489-C8ED58BB1EB8Q34475368-27A81D91-89D2-494C-A8FF-396A82B9E748Q34534253-C18C6254-594D-41FD-983F-4BB2A8B55AFDQ34596917-6D5283B2-9A73-4637-8609-58C2E8160C10Q35162513-956A796D-88DA-47A7-831C-5FB4E7D17EF7Q35760402-89AEF1BA-FF3B-4FFF-8F98-7ECFB21D699DQ36460456-B74C95CB-81A5-443C-9E47-2BDA9BD648EFQ36592439-C1F759F0-ADC2-425A-9E5F-936E9D59D179Q36824457-70421DDC-4D7D-488B-987E-068698CD3196Q36865760-E06E4551-9EA3-496B-AF2F-2B2311B5FC31Q36917055-C915A954-5E22-4D2A-AE39-4A1E3B27A245Q37100514-DBECF8D4-E503-438C-B42E-DBCE741F869EQ37234977-9CD5433D-1111-41E7-B001-D17EC1E1776EQ37272591-32749FAA-5781-46DD-A0E0-2CBE73675687Q37275225-DD3981D8-9018-4E7D-A631-CF3B5EA84929Q37416826-7C858E37-2D22-4E42-8541-521E8928F224Q37615436-7DA4A290-6E9B-4CFE-A3DF-5BA6E242F34BQ37644028-A0C339D1-BC02-4FD5-AB10-00973C99CAB3Q38157908-A04C3330-7688-48C9-A775-5AB925B2A356Q38318210-6DD19393-C329-4366-A5FE-177B2F1C5214Q38988602-EFFCC2D6-DA11-46AD-A975-350D05BA12D1Q39373439-0B2E3557-72B8-4431-8A78-34FF94E1E6FFQ39766045-D9A318F4-ECFD-4F4F-8482-CC2E9E4856CEQ39783160-0B8F140B-D29B-4D32-9313-AF9E76028C78Q40101745-E583B729-A892-45BD-92F5-AB13C7B60C0E
P2860
Three classes of inhibitors share a common binding domain in mitochondrial complex I (NADH:ubiquinone oxidoreductase).
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh-hant
name
Three classes of inhibitors sh ...... DH:ubiquinone oxidoreductase).
@en
Three classes of inhibitors share a common binding domain in mitochondrial complex I
@nl
type
label
Three classes of inhibitors sh ...... DH:ubiquinone oxidoreductase).
@en
Three classes of inhibitors share a common binding domain in mitochondrial complex I
@nl
prefLabel
Three classes of inhibitors sh ...... DH:ubiquinone oxidoreductase).
@en
Three classes of inhibitors share a common binding domain in mitochondrial complex I
@nl
P2860
P356
P1476
Three classes of inhibitors sh ...... DH:ubiquinone oxidoreductase).
@en
P2093
P2860
P304
P356
10.1074/JBC.274.5.2625
P407
P577
1999-01-01T00:00:00Z