Efflux transporters in ulcerative colitis: decreased expression of BCRP (ABCG2) and Pgp (ABCB1).
about
Drug transporters in tissues and cells relevant to sexual transmission of HIV: Implications for drug deliveryGenetic and epigenetic changes in host ABCB1 influences malaria susceptibility to Plasmodium falciparum.Tumor necrosis factor alpha increases P-glycoprotein expression in a BME-UV in vitro model of mammary epithelial cells.High ABCC2 and low ABCG2 gene expression are early events in the colorectal adenoma-carcinoma sequence.Novel understanding of ABC transporters ABCB1/MDR/P-glycoprotein, ABCC2/MRP2, and ABCG2/BCRP in colorectal pathophysiologyIntestinal permeability and its relevance for absorption and elimination.Mass spectrometry-based targeted proteomics as a tool to elucidate the expression and function of intestinal drug transporters.Colonic treatments and targets: issues and opportunities.Altered functions and expressions of drug transporters in liver, kidney and intestine in disorders of local and remote organs: possible role of oxidative stress in the pathogenesis.Molecular pathways: gene-environment interactions regulating dietary fiber induction of proliferation and apoptosis via butyrate for cancer prevention.Drug transporter pharmacogenetics in nucleoside-based therapies.Intestinal inflammation and the enterocyte transportome.Impeded protein folding and function in active inflammatory bowel disease.Inflammation-mediated changes in drug transporter expression/activity: implications for therapeutic drug response.Absolute abundance and function of intestinal drug transporters: a prerequisite for fully mechanistic in vitro-in vivo extrapolation of oral drug absorption.The impact of drug transporters on adverse drug reaction.New insights in the biology of ABC transporters ABCC2 and ABCC3: impact on drug disposition.Understanding Disease-Drug Interactions in Cancer Patients: Implications for Dosing Within the Therapeutic Window.Clinical determinants of calcineurin inhibitor disposition: a mechanistic review.Malignancies in Patients with Inflammatory Bowel Disease: Results from 20 Years of Follow-up in the IBSEN Study.CYP3A4 Activity is Markedly Lower in Patients with Crohn's Disease.Decreased sigmoidal ABCB1 (P-glycoprotein) expression in ulcerative colitis is associated with disease activity.Endotoxin-Mediated Downregulation of Hepatic Drug Transporters in HIV-1 Transgenic Rats.P-glycoprotein multidrug transporter in inflammatory bowel diseases: More questions than answers.Effect of proinflammatory cytokine IL-6 on efflux transport of rebamipide in Caco-2 cells.High gene expression of MDR1 (ABCB1) is associated with medical treatment response and long-term remission in patients with ulcerative colitis.Profiling of ABC transporters during active ulcerative colitis and in vitro effect of inflammatory modulators.Comprehensive Synthesis of Amino Acid-Derived Thiazole Peptidomimetic Analogues to Understand the Enigmatic Drug/Substrate-Binding Site of P-Glycoprotein.Drug transport into the central nervous system: using newer findings about the blood-brain barriers.Mobilization of epithelial mesenchymal transition genes distinguishes active from inactive lesional tissue in patients with ulcerative colitis.Downregulation of expression of xenobiotic efflux genes is associated with pelvic pouch inflammation in ulcerative colitis.Pro-inflammatory cytokines interleukin-1 beta, interleukin 6, and tumor necrosis factor-alpha alter the expression and function of ABCG2 in cervix and gastric cancer cells.Transporters MRP1 and MRP2 Regulate Opposing Inflammatory Signals To Control Transepithelial Neutrophil Migration during Streptococcus pneumoniae Lung Infection.Decreased Serum Bilirubin Levels and Increased Uric Acid Levels are Associated with Ulcerative Colitis
P2860
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P2860
Efflux transporters in ulcerative colitis: decreased expression of BCRP (ABCG2) and Pgp (ABCB1).
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Efflux transporters in ulcerat ...... BCRP (ABCG2) and Pgp (ABCB1).
@en
Efflux transporters in ulcerative colitis: decreased expression of BCRP
@nl
type
label
Efflux transporters in ulcerat ...... BCRP (ABCG2) and Pgp (ABCB1).
@en
Efflux transporters in ulcerative colitis: decreased expression of BCRP
@nl
prefLabel
Efflux transporters in ulcerat ...... BCRP (ABCG2) and Pgp (ABCB1).
@en
Efflux transporters in ulcerative colitis: decreased expression of BCRP
@nl
P2093
P2860
P356
P1476
Efflux transporters in ulcerat ...... BCRP (ABCG2) and Pgp (ABCB1).
@en
P2093
Anders Rönnblom
Andreas Kindmark
Annica Jacobson
Fredrik Rorsman
Gunilla Englund
Per Artursson
P2860
P304
P356
10.1002/IBD.20030
P577
2007-03-01T00:00:00Z