A mutant alphaII-spectrin designed to resist calpain and caspase cleavage questions the functional importance of this process in vivo.
about
Spectrin-based skeleton as an actor in cell signalingSPTAN1 encephalopathy: distinct phenotypes and genotypes.Dominant-negative mutations in alpha-II spectrin cause West syndrome with severe cerebral hypomyelination, spastic quadriplegia, and developmental delay.Proximal giant neurofilamentous axonopathy in mice genetically engineered to resist calpain and caspase cleavage of α-II spectrin.Quantitative studies of caspase-3 catalyzed αII-spectrin breakdown.Amyloid-beta42 signals tau hyperphosphorylation and compromises neuronal viability by disrupting alkylacylglycerophosphocholine metabolism.Gene Array Analyzer: alternative usage of gene arrays to study alternative splicing eventsInhibition of calpain but not caspase activity by spectrin fragments.The suppression of epileptiform discharges in cultured hippocampal neurons is regulated via alterations in full-length tropomyosin-related kinase type B receptors signalling activity.
P2860
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P2860
A mutant alphaII-spectrin designed to resist calpain and caspase cleavage questions the functional importance of this process in vivo.
description
2007 nî lūn-bûn
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name
A mutant alphaII-spectrin desi ...... tance of this process in vivo.
@en
A mutant alphaII-spectrin desi ...... tance of this process in vivo.
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type
label
A mutant alphaII-spectrin desi ...... tance of this process in vivo.
@en
A mutant alphaII-spectrin desi ...... tance of this process in vivo.
@nl
prefLabel
A mutant alphaII-spectrin desi ...... tance of this process in vivo.
@en
A mutant alphaII-spectrin desi ...... tance of this process in vivo.
@nl
P2860
P50
P356
P1476
A mutant alphaII-spectrin desi ...... rtance of this process in vivo
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Fleur Meary
Marie-Christine Lecomte
P2860
P304
14226-14237
P356
10.1074/JBC.M700028200
P407
P577
2007-03-20T00:00:00Z