NSC348884, a nucleophosmin inhibitor disrupts oligomer formation and induces apoptosis in human cancer cells.
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NPM1/B23: A Multifunctional Chaperone in Ribosome Biogenesis and Chromatin RemodelingNucleophosmin: from structure and function to disease developmentMolecules that target nucleophosmin for cancer treatment: an updateStructural polymorphism in the N-terminal oligomerization domain of NPM1Insights into the regulation of neuronal viability by nucleophosmin/B23A phthalimide derivative that inhibits centrosomal clustering is effective on multiple myelomaA novel phthalimide derivative, TC11, has preclinical effects on high-risk myeloma cells and osteoclastsA computational strategy to select optimized protein targets for drug development toward the control of cancer diseasesNucleolar stress is an early response to myocardial damage involving nucleolar proteins nucleostemin and nucleophosminGLTSCR2 is an upstream negative regulator of nucleophosmin in cervical cancer.Targeting nucleophosmin 1 represents a rational strategy for radiation sensitization.Inhibition of protein phosphorylation in MIA pancreatic cancer cells: confluence of metabolic and signaling pathways.Nucleophosmin phosphorylation by v-cyclin-CDK6 controls KSHV latency.Localization and altered expression of nucleophosmin in the nuclear matrix during the differentiation of human hepatocarcinoma SMMC-7721 cells induced by HMBA.Selective gene-expression profiling of migratory tumor cells in vivo predicts clinical outcome in breast cancer patients.Aberrant expression of nuclear matrix proteins during HMBA-induced differentiation of gastric cancer cellsAKT regulates NPM dependent ARF localization and p53mut stability in tumors.A redox mechanism underlying nucleolar stress sensing by nucleophosminIdentification of FUSE-binding protein 1 as a regulatory mRNA-binding protein that represses nucleophosmin translation.The novel chemical entity YTR107 inhibits recruitment of nucleophosmin to sites of DNA damage, suppressing repair of DNA double-strand breaks and enhancing radiosensitizationDynamic conformations of nucleophosmin (NPM1) at a key monomer-monomer interface affect oligomer stability and interactions with granzyme B.Interactions of the natural product (+)-avrainvillamide with nucleophosmin and exportin-1 Mediate the cellular localization of nucleophosmin and its AML-associated mutants.NPM and BRG1 Mediate Transcriptional Resistance to Retinoic Acid in Acute Promyelocytic LeukemiaRole of nucleophosmin in acute myeloid leukemia.Nucleophosmin/B23 is a negative regulator of estrogen receptor α expression via AP2γ in endometrial cancer cells.Nucleophosmin Regulates Intracellular Oxidative Stress Homeostasis via Antioxidant PRDX6.Nucleophosmin1 associated with drug resistance and recurrence of bladder cancer.Sensitivity of tumor cells towards CIGB-300 anticancer peptide relies on its nucleolar localization.Human papillomavirus type 16 E6/E7 upregulation of nucleophosmin is important for proliferation and inhibition of differentiation.NPM1 directs PIDDosome-dependent caspase-2 activation in the nucleolus.Nucleophosmin modulates the alleviation of atopic dermatitis caused by the marine-derived compound dihydroaustrasulfone alcohol.Phosphoproteome Profiling Reveals Multifunctional Protein NPM1 as part of the Irradiation Response of Tumor Cells
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P2860
NSC348884, a nucleophosmin inhibitor disrupts oligomer formation and induces apoptosis in human cancer cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
NSC348884, a nucleophosmin inh ...... optosis in human cancer cells.
@en
NSC348884, a nucleophosmin inh ...... optosis in human cancer cells.
@nl
type
label
NSC348884, a nucleophosmin inh ...... optosis in human cancer cells.
@en
NSC348884, a nucleophosmin inh ...... optosis in human cancer cells.
@nl
prefLabel
NSC348884, a nucleophosmin inh ...... optosis in human cancer cells.
@en
NSC348884, a nucleophosmin inh ...... optosis in human cancer cells.
@nl
P2093
P356
P1433
P1476
NSC348884, a nucleophosmin inh ...... optosis in human cancer cells.
@en
P2093
A Stejskal
D Mahadevan
K Shakalya
P2860
P2888
P304
P356
10.1038/ONC.2008.54
P407
P577
2008-03-17T00:00:00Z