Flubendazole: a candidate macrofilaricide for lymphatic filariasis and onchocerciasis field programs.
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Repurposing drugs for the treatment and control of helminth infectionsResearch for new drugs for elimination of onchocerciasis in AfricaExploring the potential of flubendazole in filariasis control: evaluation of the systemic exposure for different pharmaceutical preparationsControl, elimination, and eradication of river blindness: scenarios, timelines, and ivermectin treatment needs in AfricaAn In Vitro/In Vivo Model to Analyze the Effects of Flubendazole Exposure on Adult Female Brugia malayiThe potential impact of moxidectin on onchocerciasis elimination in Africa: an economic evaluation based on the Phase II clinical trial dataA murine macrofilaricide pre-clinical screening model for onchocerciasis and lymphatic filariasisOcular onchocerciasis: current management and future prospectsFlubendazole, FDA-approved anthelmintic, targets breast cancer stem-like cells.A histochemical study of the Nras/let-60 activity in filarial nematodes.In vitro flubendazole-induced damage to vital tissues in adult females of the filarial nematode Brugia malayi.Genotoxicity of flubendazole and its metabolites in vitro and the impact of a new formulation on in vivo aneugenicity.Pharmacokinetic comparison of different flubendazole formulations in pigs: A further contribution to its development as a macrofilaricide molecule.Stage-specific Proteomes from Onchocerca ochengi, Sister Species of the Human River Blindness Parasite, Uncover Adaptations to a Nodular Lifestyle.Profiling the macrofilaricidal effects of flubendazole on adult female Brugia malayi using RNAseq.Progress and challenges in the discovery of macrofilaricidal drugs.Present-day anthelmintics and perspectives on future new targets.Flubendazole induces mitotic catastrophe and senescence in colon cancer cells in vitro.Species differences in hepatic biotransformation of the anthelmintic drug flubendazole.Oral bioavailability enhancement of flubendazole by developing nanofibrous solid dosage forms.Macrofilaricidal Efficacy of Repeated Doses of Ivermectin for the Treatment of River Blindness.Potential Role for Flubendazole in Limiting Filariasis Transmission: Observations of Microfilarial Sensitivity.Repurposing and Reformulation of the Antiparasitic Agent Flubendazole for Treatment of Cryptococcal Meningoencephalitis, a Neglected Fungal Disease.Alternative treatment strategies to accelerate the elimination of onchocerciasis.Heterogeneity in the in vitro susceptibility of Loa loa microfilariae to drugs commonly used in parasitological infections.Flubendazole inhibits glioma proliferation by G2/M cell cycle arrest and pro-apoptosis.Adding "Filaricide" to the Gleevec Portfolio.
P2860
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P2860
Flubendazole: a candidate macrofilaricide for lymphatic filariasis and onchocerciasis field programs.
description
2011 nî lūn-bûn
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2011年の論文
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2011年学术文章
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name
Flubendazole: a candidate macr ...... onchocerciasis field programs.
@en
Flubendazole: a candidate macr ...... onchocerciasis field programs.
@nl
type
label
Flubendazole: a candidate macr ...... onchocerciasis field programs.
@en
Flubendazole: a candidate macr ...... onchocerciasis field programs.
@nl
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Flubendazole: a candidate macr ...... onchocerciasis field programs.
@en
Flubendazole: a candidate macr ...... onchocerciasis field programs.
@nl
P2860
P921
P356
P1476
Flubendazole: a candidate macr ...... onchocerciasis field programs.
@en
P2093
Charles D Mackenzie
Timothy G Geary
P2860
P304
P356
10.1586/ERI.11.30
P577
2011-05-01T00:00:00Z