Tet2-Mediated Clonal Hematopoiesis Accelerates Heart Failure Through a Mechanism Involving the IL-1β/NLRP3 Inflammasome.

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Somatic Mutations and Clonal Hematopoiesis: Unexpected Potential New Drivers of Age-Related Cardiovascular Disease.CRISPR-Mediated Gene Editing to Assess the Roles of Tet2 and Dnmt3a in Clonal Hematopoiesis and Cardiovascular Disease Targeting NLRP3 Inflammasome in the Treatment of CNS Diseases

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P2860

Tet2-Mediated Clonal Hematopoiesis Accelerates Heart Failure Through a Mechanism Involving the IL-1β/NLRP3 Inflammasome.

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http://www.wikidata.org/entity/Q52730911

description

2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年學術文章

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2018年學術文章

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name

Tet2-Mediated Clonal Hematopoi ...... the IL-1β/NLRP3 Inflammasome.

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Tet2-Mediated Clonal Hematopoi ...... the IL-1β/NLRP3 Inflammasome.

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type

Item

label

Tet2-Mediated Clonal Hematopoi ...... the IL-1β/NLRP3 Inflammasome.

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Tet2-Mediated Clonal Hematopoi ...... the IL-1β/NLRP3 Inflammasome.

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Tet2-Mediated Clonal Hematopoi ...... the IL-1β/NLRP3 Inflammasome.

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Tet2-Mediated Clonal Hematopoi ...... the IL-1β/NLRP3 Inflammasome.

@nl

P1476

Tet2-Mediated Clonal Hematopoi ...... g the IL-1β/NLRP3 Inflammasome

@en

P2093

David Goukassian

http://www.w3.org/2001/XMLSchema#string

Kenneth Walsh

http://www.w3.org/2001/XMLSchema#string

Kosei Oshima

http://www.w3.org/2001/XMLSchema#string

Matthew A Cooper

http://www.w3.org/2001/XMLSchema#string

Miho Sano

http://www.w3.org/2001/XMLSchema#string

Minoru Yoshiyama

http://www.w3.org/2001/XMLSchema#string

Soichi Sano

http://www.w3.org/2001/XMLSchema#string

Yasufumi Katanasaka

http://www.w3.org/2001/XMLSchema#string

Ying Wang

http://www.w3.org/2001/XMLSchema#string

P2860

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

Cardiac myocyte follistatin-like 1 functions to attenuate hypertrophy following pressure overload

Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence

Leukemia-associated somatic mutations drive distinct patterns of age-related clonal hemopoiesis

TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis

Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation

Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice

Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies

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875-886

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scholarly article

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10.1016/J.JACC.2017.12.037

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English

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José J Fuster

Susan MacLauchlan

María A Zuriaga

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2018-02-01T00:00:00Z

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29471939

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P921

heart failure

inflammasome

haematopoiesis

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5828038

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Tet2-Mediated Clonal Hematopoiesis Accelerates Heart Failure Through a Mechanism Involving the IL-1β/NLRP3 Inflammasome.

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P2860

P2860

Tet2-Mediated Clonal Hematopoiesis Accelerates Heart Failure Through a Mechanism Involving the IL-1β/NLRP3 Inflammasome.

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