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Anticancer activity of newly synthesized azaphenothiazines from NCI's anticancer screening bank.Discovery of butyrylcholinesterase inhibitors among derivatives of azaphenothiazines.N-[4-(9-Chloro-quino[3,2-b]benzo[1,4]thia-zin-6-yl)but-yl]acetamide.Synthesis and anticancer and lipophilic properties of 10-dialkylaminobutynyl derivatives of 1,8- and 2,7-diazaphenothiazines.Synthesis and biological evaluation of novel propargylquinobenzothiazines and their derivatives as potential antiproliferative, anti-inflammatory, and anticancer agents.3,6-Diazaphenothiazines as potential lead molecules - synthesis, characterization and anticancer activity.6-Substituted 9-fluoroquino[3,2-b]benzo[1,4]thiazines display strong antiproliferative and antitumor properties.6-[3-(p-Tolyl-sulfonyl-amino)-prop-yl]diquino-thia-zine.Azaphenothiazines - promising phenothiazine derivatives. An insight into nomenclature, synthesis, structure elucidation and biological properties.Synthesis, spectroscopic characterization, and anticancer activity of new 10-substituted 1,6-diazaphenothiazines.Synthesis of quinoline/naphthalene-containing azaphenothiazines and their potent in vitro antioxidant properties.Synthesis and selected immunological properties of 10-substituted 1,8-diazaphenothiazines.The immunosuppressive activities of newly synthesized azaphenothiazines in human and mouse models.10H-3,6-Diazaphenothiazine induces G2/M phase cell cycle arrest and caspase-dependent apoptosis and inhibits cell invasion of A2780 ovarian carcinoma cells through the regulation of NF-κB and (BIRC6-XIAP) complexes.Estimation of the lipophilicity of new anticancer and immunosuppressive 1,8-diazaphenothiazine derivatives.Selected azaphenothiazines inhibit delayed type hypersensitivity and carrageenan reaction in mice.Topically applied azaphenothiazines inhibit experimental psoriasis in mice.Topically applied azaphenothiazines inhibit contact sensitivity to oxazolone in mice.Thin-layer chromatographic detection of new azaphenothiazinesDesign, Synthesis, and Structural Characterization of Novel Diazaphenothiazines with 1,2,3-Triazole Substituents as Promising Antiproliferative Agents10H-1,9-diazaphenothiazine and its 10-derivatives: synthesis, characterisation and biological evaluation as potential anticancer agentsDual Action of Dipyridothiazine and Quinobenzothiazine Derivatives-Anticancer and Cholinesterase-Inhibiting Activity
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hulumtuese
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հետազոտող
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Małgorzata Jeleń
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Małgorzata Jeleń
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Małgorzata Jeleń
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Małgorzata Jeleń
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Małgorzata Jeleń
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Małgorzata Jeleń
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Małgorzata Jeleń
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Małgorzata Jeleń
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Małgorzata Jeleń
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Małgorzata Jeleń
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Małgorzata Jeleń
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Małgorzata Jeleń
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Małgorzata Jeleń
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Małgorzata Jeleń
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Małgorzata Jeleń
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Małgorzata Jeleń
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Małgorzata Jeleń
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Małgorzata Jeleń
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P1153
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P31
P3124
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0000-0002-4144-990X
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viaf-5926152684024623430002