A Small-Molecule Inhibitor of WEE1, AZD1775, Synergizes with Olaparib by Impairing Homologous Recombination and Enhancing DNA Damage and Apoptosis in Acute Leukemia.
about
Increased activity of both CDK1 and CDK2 is necessary for the combinatorial activity of WEE1 inhibition and cytarabine.PARP inhibitors: Clinical utility and possibilities of overcoming resistance.Identification of relevant drugable targets in diffuse large B-cell lymphoma using a genome-wide unbiased CD20 guilt-by association approach.AZD1775 Increases Sensitivity to Olaparib and Gemcitabine in Cancer Cells with p53 Mutations.Rucaparib: a novel PARP inhibitor for BRCA advanced ovarian cancer.Augmentation of the therapeutic efficacy of WEE1 kinase inhibitor AZD1775 by inhibiting the YAP-E2F1-DNA damage response pathway axis.
P2860
A Small-Molecule Inhibitor of WEE1, AZD1775, Synergizes with Olaparib by Impairing Homologous Recombination and Enhancing DNA Damage and Apoptosis in Acute Leukemia.
description
2017 nî lūn-bûn
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2017年の論文
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name
A Small-Molecule Inhibitor of ...... d Apoptosis in Acute Leukemia.
@en
A Small-Molecule Inhibitor of ...... d Apoptosis in Acute Leukemia.
@nl
type
label
A Small-Molecule Inhibitor of ...... d Apoptosis in Acute Leukemia.
@en
A Small-Molecule Inhibitor of ...... d Apoptosis in Acute Leukemia.
@nl
prefLabel
A Small-Molecule Inhibitor of ...... d Apoptosis in Acute Leukemia.
@en
A Small-Molecule Inhibitor of ...... d Apoptosis in Acute Leukemia.
@nl
P2093
P2860
P1476
A Small-Molecule Inhibitor of ...... d Apoptosis in Acute Leukemia.
@en
P2093
Chengjing Zhou
Christopher C Porter
Craig T Jordan
Dmitry Baturin
Jonathan C Snedeker
Lori Gardner
Rajeev Vibhakar
Sujatha Venkataraman
Susan P Fosmire
Tamara B Garcia
P2860
P304
P356
10.1158/1535-7163.MCT-16-0660
P577
2017-06-27T00:00:00Z