Enhanced DNA repair as a mechanism of resistance to cis-diamminedichloroplatinum(II).
about
CROP/Luc7A, a novel serine/arginine-rich nuclear protein, isolated from cisplatin-resistant cell lineGlutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapyCisplatin-resistant cells express increased levels of a factor that recognizes damaged DNA.Gli1 contributes to cellular resistance to cisplatin through altered cellular accumulation of the drug.Alkylating agents and immunotoxins exert synergistic cytotoxic activity against ovarian cancer cells. Mechanism of action.Glutathione and drug resistance.Apoptosis-related mRNA expression profiles of ovarian cancer cell lines following cisplatin treatment.Oxaliplatin: a review of evolving concepts.Differential human nucleotide excision repair of paired and mispaired cisplatin-DNA adducts.Strategic down-regulation of DNA polymerase beta by antisense RNA sensitizes mammalian cells to specific DNA damaging agents.Novel role of base excision repair in mediating cisplatin cytotoxicity.New clues for platinum antitumor chemistry: kinetically controlled metal binding to DNA.New therapies for ovarian cancer.Acquired cisplatin resistance in human ovarian cancer cells is associated with enhanced repair of cisplatin-DNA lesions and reduced drug accumulation.Repair synthesis by human cell extracts in cisplatin-damaged DNA is preferentially determined by minor adductsCisplatin-DNA damage recognition proteins in human tumour extracts.Relationship between the exposure to cisplatin, DNA-adduct formation in leucocytes and tumour response in patients with solid tumoursModulation of sensitivity to cis-diamminedichloroplatinum (II) by thromboxane A2 receptor antagonists in non-small-cell lung cancer cell lines.Aphidicolin markedly increases the platinum sensitivity of cells from primary ovarian tumours.Role of mismatch repair proteins in the processing of cisplatin interstrand cross-links.An increase in glucosylceramide synthase induces Bcl-xL-mediated cell survival in vinorelbine-resistant lung adenocarcinoma cells.Relationship between folate-binding protein expression and cisplatin sensitivity in ovarian carcinoma cell lines.An XPG DNA repair defect causing mutagen hypersensitivity in mouse leukemia L1210 cells.Lack of EGF receptor contributes to drug sensitivity of human germline cellsLoss of DNA mismatch repair facilitates reactivation of a reporter plasmid damaged by cisplatinAdaptive intrapatient dose escalation of cisplatin in combination with low-dose vp16 in patients with nonsmall cell lung cancer.Cross-resistance to UV radiation of a cisplatin-resistant human cell line: overexpression of cellular factors that recognize UV-modified DNAIncreased gene-specific repair of cisplatin interstrand cross-links in cisplatin-resistant human ovarian cancer cell lines.Co-treatment by docetaxel and vinblastine breaks down P-glycoprotein mediated chemo-resistance.Epistatic role of base excision repair and mismatch repair pathways in mediating cisplatin cytotoxicityAn intrastrand d(GpG) platinum crosslink in duplex M13 DNA is refractory to repair by human cell extracts.The synergism between Belotecan and cisplatin in gastric cancer.Overcoming challenges of ovarian cancer stem cells: novel therapeutic approaches.Natural compounds to overcome cancer chemoresistance: toxicological and clinical issues.Cisplatin resistance by induction of aldo-keto reductase family 1 member C2 in human bladder cancer cellsAn in vivo highly antitumor-active tetrazolato-bridged dinuclear platinum(II) complex largely circumvents in vitro cisplatin resistance: two linkage isomers yield the same product upon reaction with 9-ethylguanine but exhibit different cytotoxic proAdseverin: a novel cisplatin-resistant marker in the human bladder cancer cell line HT1376 identified by quantitative proteomic analysis.Thioredoxin reductase inhibitor ethaselen increases the drug sensitivity of the colon cancer cell line LoVo towards cisplatin via regulation of G1 phase and reversal of G2/M phase arrest.Augmentation of cisplatin sensitivity in cisplatin-resistant human bladder cancer cells by modulating glutathione concentrations and glutathione-related enzyme activities.Human nucleotide excision repair in vitro: repair of pyrimidine dimers, psoralen and cisplatin adducts by HeLa cell-free extract.
P2860
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P2860
Enhanced DNA repair as a mechanism of resistance to cis-diamminedichloroplatinum(II).
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年学术文章
@wuu
1988年学术文章
@zh
1988年学术文章
@zh-cn
1988年学术文章
@zh-hans
1988年学术文章
@zh-my
1988年学术文章
@zh-sg
1988年學術文章
@yue
1988年學術文章
@zh-hant
name
Enhanced DNA repair as a mechanism of resistance to cis-diamminedichloroplatinum
@nl
Enhanced DNA repair as a mechanism of resistance to cis-diamminedichloroplatinum(II).
@en
type
label
Enhanced DNA repair as a mechanism of resistance to cis-diamminedichloroplatinum
@nl
Enhanced DNA repair as a mechanism of resistance to cis-diamminedichloroplatinum(II).
@en
prefLabel
Enhanced DNA repair as a mechanism of resistance to cis-diamminedichloroplatinum
@nl
Enhanced DNA repair as a mechanism of resistance to cis-diamminedichloroplatinum(II).
@en
P4510
P356
P1433
P1476
Enhanced DNA repair as a mechanism of resistance to cis-diamminedichloroplatinum(II).
@en
P2093
P304
P356
10.1021/BI00413A022
P407
P577
1988-06-01T00:00:00Z