Steady-state analysis of kinetic isotope effects in enzymic reactions.
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The Mycobacterium tuberculosis Rv2540c DNA sequence encodes a bifunctional chorismate synthaseKinetic deuterium isotope effects in cytochrome P450 oxidation reactionsAdvances in kinetic isotope effect measurement techniques for enzyme mechanism studyA Radical Transfer Pathway in Spore Photoproduct LyaseMg 2+ Binds to the Surface of Thymidylate Synthase and Affects Hydride Transfer at the Interior Active SiteUse of isotope effects to elucidate enzyme mechanismsInfluence of the position of the double bond in steroid substrates on the efficiency of the proton-transfer reaction by Pseudomonas testosteroni 3-oxo-steroid delta 4-delta 5-isomeraseThe Influence of Growth Rate on 2H/1H Fractionation in Continuous Cultures of the Coccolithophorid Emiliania huxleyi and the Diatom Thalassiosira pseudonanaCopper active sites in biologyLinking protein structure and dynamics to catalysis: the role of hydrogen tunnelling.Insights into the Activity Change of Spore Photoproduct Lyase Induced by Mutations at a Peripheral Glycine ResidueThe role of enzyme dynamics and tunnelling in catalysing hydride transfer: studies of distal mutants of dihydrofolate reductase.Effects of a distal mutation on active site chemistry.New insights into rotating frame relaxation at high field.Oxidation of N-Nitrosoalkylamines by human cytochrome P450 2A6: sequential oxidation to aldehydes and carboxylic acids and analysis of reaction stepsChemical Mechanism of the Branched-Chain Aminotransferase IlvE from Mycobacterium tuberculosis.Update 1 of: Tunneling and dynamics in enzymatic hydride transfer.NMR method for measuring carbon-13 isotopic enrichment of metabolites in complex solutions.Synthesis of 11-thialinoleic acid and 14-thialinoleic acid, inhibitors of soybean and human lipoxygenasesStereospecificity and kinetic mechanism of human prenylcysteine lyase, an unusual thioether oxidase.Kinetic and chemical mechanism of the dihydrofolate reductase from Mycobacterium tuberculosisThe use of isotope effects to determine enzyme mechanisms.Kinetic analysis of lauric acid hydroxylation by human cytochrome P450 4A11Cytochrome P450 7A1 cholesterol 7alpha-hydroxylation: individual reaction steps in the catalytic cycle and rate-limiting ferric iron reductionMechanistic studies of 1-aminocyclopropane-1-carboxylate deaminase: characterization of an unusual pyridoxal 5'-phosphate-dependent reaction.Kinetic isotope effects in Ras-catalyzed GTP hydrolysis: evidence for a loose transition state.Femtosecond dynamics coupled to chemical barrier crossing in a Born-Oppenheimer enzyme.Cytochrome P450: what have we learned and what are the future issues?Kinetic isotope effects reveal early transition state of protein lysine methyltransferase SET8.Mechanistic studies of the spore photoproduct lyase via a single cysteine mutationOxidation of methyl and ethyl nitrosamines by cytochrome P450 2E1 and 2B1EPR-kinetic isotope effect study of the mechanism of radical-mediated dehydrogenation of an alcohol by the radical SAM enzyme DesII.Isotope effect in peroxidation of deuterium-labelled ethanol by liver catalase.Recycling nicotinamide. The transition-state structure of human nicotinamide phosphoribosyltransferase.Kinetic isotope effects for fast deuterium and proton exchange ratesPre-steady-state studies of phosphite dehydrogenase demonstrate that hydride transfer is fully rate limitingTransition state analysis of model and enzymatic prenylation reactionsTransition states of Plasmodium falciparum and human orotate phosphoribosyltransferases.The power of integrating kinetic isotope effects into the formalism of the Michaelis-Menten equation.Why nature really chose phosphate.
P2860
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P2860
Steady-state analysis of kinetic isotope effects in enzymic reactions.
description
1975 nî lūn-bûn
@nan
1975年の論文
@ja
1975年学术文章
@wuu
1975年学术文章
@zh
1975年学术文章
@zh-cn
1975年学术文章
@zh-hans
1975年学术文章
@zh-my
1975年学术文章
@zh-sg
1975年學術文章
@yue
1975年學術文章
@zh-hant
name
Steady-state analysis of kinetic isotope effects in enzymic reactions.
@en
Steady-state analysis of kinetic isotope effects in enzymic reactions.
@nl
type
label
Steady-state analysis of kinetic isotope effects in enzymic reactions.
@en
Steady-state analysis of kinetic isotope effects in enzymic reactions.
@nl
prefLabel
Steady-state analysis of kinetic isotope effects in enzymic reactions.
@en
Steady-state analysis of kinetic isotope effects in enzymic reactions.
@nl
P356
P1433
P1476
Steady-state analysis of kinetic isotope effects in enzymic reactions.
@en
P2093
Northrop DB
P304
P356
10.1021/BI00683A013
P407
P577
1975-06-01T00:00:00Z