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The Eighth Central European Conference "Chemistry towards Biology": SnapshotAnti-mycobacterial activity of 1,3-diaryltriazenes.Pt(II) complexes with N-(3-pyridyl)-2-(4-(trifluoromethyl)phenyl)diazenecarboxamide and their reactions with glutathione.1-(2-Picolyl)-substituted 1,2,3-triazole as novel chelating ligand for the preparation of ruthenium complexes with potential anticancer activity.A selective approach to pyridine appended 1,2,3-triazolium salts.Discovery of 'click' 1,2,3-triazolium salts as potential anticancer drugs.Combining [arene-Ru] with azocarboxamide to generate a complex with cytotoxic properties.Biological evaluation of diazene derivatives as anti-tubercular compounds.2-Hy-droxy-2-methyl-1-phenyl-indolin-3-one.Selective cytotoxicity of diazenecarboxamides towards human leukemic cell lines.The 1,3-diaryltriazenido(p-cymene)ruthenium(II) complexes with a high in vitro anticancer activity.3-Ethyl-3-hy-droxy-8-meth-oxy-quinoline-2,4(1H,3H)-dione monohydrate.3-Ethyl-4-hy-droxy-8-meth-oxy-quinolin-2(1H)-one.New series of isoniazid hydrazones linked with electron-withdrawing substituents.Lactone pathway to statins utilizing the Wittig reaction. The synthesis of rosuvastatin.Cytotoxic effects of diazenes on tumor cells in vitro.Diazenecarboxamide UP-91, a potential anticancer agent, acts by reducing cellular glutathione content.Unfunctionalized, alpha-epimerizable nonracemic ketones and aldehydes can be accessed by crystallization-induced dynamic resolution of imines.Evaluation of the enantiomeric resolution of 7,8-dihydroxy-7,8-dihydrobenzo[a]-pyrene and its 6-fluoro and 6-bromo derivatives on polysaccharide-derived stationary phases.Design, Syntheses, and in Vitro Evaluation of New Fluorine-18 Radiolabeled Tau-Labeling Molecular Probes.Synthesis and in vitro investigation of halogenated 1,3-bis(4-nitrophenyl)triazenide salts as antitubercular compounds.Design, synthesis and antitubercular potency of 4-hydroxyquinolin-2(1H)-ones.A mesoionic bis(Py-tzNHC) palladium(II) complex catalyses "green" Sonogashira reaction through an unprecedented mechanism.En Route to 2-(Cyclobuten-1-yl)-3-(trifluoromethyl)-1H-indole.Synthesis and X-ray Structural Analysis of the Ruthenium(III) Complex Na[trans-RuCl4(DMSO) (PyrDiaz)], the Diazene Derivative of Antitumor NAMI-Pyr.Diaryltriazenes as antibacterial agents against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium smegmatis.RuII, IrIII and OsII mesoionic carbene complexes: efficient catalysts for transfer hydrogenation of selected functionalities.Ru(II), Os(II), and Ir(III) complexes with chelating pyridyl-mesoionic carbene ligands: structural characterization and applications in transfer hydrogenation catalysis.Catalytic oxygenation of sp3 "C-H" bonds with Ir(III) complexes of chelating triazoles and mesoionic carbenes.Synthesis of Bis(1,2,3-Triazole) Functionalized Quinoline-2,4-DionesMechanism of copper-free Sonogashira reaction operates through palladium-palladium transmetallationPyridyl Conjugated 1,2,3-Triazole is a Versatile Coordination Ability Ligand Enabling Supramolecular AssociationsX-Ray crystallographic, NMR and antimicrobial activity studies of magnesium complexes of fluoroquinolones – racemic ofloxacin and its S-form, levofloxacinRuthenium Azocarboxamide Half-Sandwich Complexes: Influence of the Coordination Mode on the Electronic Structure and Activity in Base-Free Transfer Hydrogenation CatalysisExploring the Scope of Pyridyl- and Picolyl-Functionalized 1,2,3-Triazol-5-ylidenes in Bidentate Coordination to Ruthenium(II) Cymene Chloride ComplexesNovel ring contraction of 3-hydroxy-2,4(1H,3H)-quinolinediones in aqueous alkali. The first convenient route to 2-hydroxyindoxylsFormation and structure elucidation of two novel spiro[2H-indol]-3(1H)-onesFischer indolisation of N-(α-ketoacyl)anthranilic acids into 2-(indol-2-carboxamido)benzoic acids and 2-indolyl-3,1-benzoxazin-4-ones and their NMR studyPlatinum-mediated dinitrogen liberation from 2-picolyl azide through a putative Pt═N double bond containing intermediateCompletely stereocontrolled aldol reaction of chiral β-amino acids
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հետազոտող
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Janez Košmrlj
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Janez Košmrlj
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Janez Košmrlj
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Janez Košmrlj
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Janez Košmrlj
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Janez Košmrlj
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Janez Košmrlj
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Janez Košmrlj
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Janez Košmrlj
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Janez Košmrlj
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Janez Košmrlj
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Janez Košmrlj
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Janez Košmrlj
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Janez Košmrlj
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Janez Košmrlj
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P106
P31
P496
0000-0002-3533-0419